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Red yeast prepn containing active components of glossy ganoderma and its prepn process

A technology of active ingredients and red yeast rice, which is applied in the field of improvement of health food components, can solve the problems of long production cycle, difficult expansion of production scale, and difficult separation and extraction of biological active substances, and achieve the effect of advanced technology

Active Publication Date: 2005-07-13
XIAN LIJUN PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Red yeast rice at home and abroad is mostly produced by solid-state fermentation, which has many disadvantages, such as long production cycle, large production labor, difficult expansion of production scale, difficult separation and extraction of biologically active substances, and difficult determination, etc.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] Embodiment 1: preparation of red yeast rice oral liquid

[0044] Preparation of fermenter culture medium (by 1 liter ratio: 20g of rice flour, 5g of sodium nitrate, 2g of potassium dihydrogen phosphate, 2g of magnesium phosphate heptahydrate, and add water to make up the rest of the volume) to sterilize; insert the seeds of purple red yeast rice into the fermenter, 27 Cultivate at ℃ for 5 days to obtain the red yeast rice fermentation liquid. Add the ganoderma lucidum fermented liquid according to the volume of 1:1, fully stir evenly, and filter to obtain the filtrate and solid matter. Add acesulfame-K at 0.25mg / g to the filtrate, pack and sterilize to obtain the red yeast rice oral liquid, the content of main functional components: crude polysaccharide 5mg / 100g, total flavonoids 4.5mg / 100g, lovastatin 0.16mg / 100g.

Embodiment 2

[0045] Embodiment 2: preparation of red yeast rice oral liquid

[0046] Preparation of fermenter culture medium (by 1 liter ratio: 800g of ganoderma lucidum fermented liquid, 4g of sodium nitrate, 1g of potassium dihydrogen phosphate, 2g of magnesium phosphate heptahydrate, the remaining volume is supplemented with water) for sterilization; Cultured at 26°C for 7 days. The fermentation broth is filtered to obtain a filtrate and a solid. Add acesulfame potassium to the filtrate at 0.1 mg / g, subpackage and sterilize to obtain the red yeast rice oral liquid, the content of main functional components: crude polysaccharide 10 mg / 100 g, total flavonoids 9 mg / 100 g, lovastatin 0.30 mg / 100 g.

Embodiment 3

[0047] Embodiment 3: preparation of red yeast rice oral liquid

[0048] Preparation of fermenter culture medium (according to 1 liter ratio: 50g of ganoderma lucidum powder, 3.5g of sodium nitrate, 2g of potassium dihydrogen phosphate, 1.5g of magnesium phosphate heptahydrate, and add water to make up the remaining volume) for sterilization; put the seeds of purple red yeast rice into the fermenter , cultured at 27°C for 6 days. The fermentation broth is filtered to obtain a filtrate and a solid. Add acesulfame potassium to the filtrate at 0.2 mg / g, subpackage and sterilize to obtain the red yeast rice oral liquid, the content of main functional components: crude polysaccharide 6.5 mg / 100 g, total flavonoids 5.4 mg / 100 g, lovastatin 0.17 mg / 100 g.

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PUM

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Abstract

The present invention provides one kind of red yeast preparation containing the active components of glossy ganoderma and its preparation process. The present invention is prepared with red yeast leavening containing the active components of glossy ganoderma and contains the main functional components including coarse polysaccharide not less than 4 mg each 100 g, total flavone not less than 3 mg each 100 g and lovastatin not less than 0.1 mg each 100 g. It may be prepared into oral liquid, soft capsule, powder, capsule, tablet, honeyed bolus, ointment, food additive and other preparation forms. The present invention includes many kinds of physiologically active matters, including polysaccharide, flavone, lovastatin, unsaturated fatty acid, protein, amino acid, etc. and has the synergistic blood fat reducing effect of red yeast and liver protecting effect of glossy ganoderma.

Description

technical field [0001] The invention belongs to the improvement of health food components, and particularly relates to the technical field of liquid fermentation. Background technique [0002] Red yeast rice is the koji produced by the fungus Monascus sp. (including Monascus sp., including Monascus sp. and Monascus purple) that exists in nature. Because it is dark red and produces red pigment, it has been called red yeast rice since ancient times. Red yeast rice has been used in my country for thousands of years. It is traditionally used in pigments, food fermentation and wine brewing, and is widely used in beverages, food, cosmetics and other fields. According to the "Compendium of Materia Medica", red yeast rice has the function of "digesting food and promoting blood circulation, invigorating the spleen and drying the stomach". Modern studies have found that red yeast rice has many medicinal effects: regulating blood lipids, lowering blood sugar, antibacterial, anti-cance...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/10A23L33/105A61K9/00A61K31/715A61P1/16A61P3/06
Inventor 赵振伟陈立王一心任建鸽纪维
Owner XIAN LIJUN PHARMA CO LTD
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