Medicinal coating production for vascular stand and electrostatic spraying apparatus

A vascular stent and drug coating technology, applied in the field of medical devices, can solve the problems of loss of paint, difficult control of gas pressure, and reduced coating efficiency, and achieve the effects of improving utilization, increasing speed, and improving efficiency.
CN1644184AInactive Publication Date: 2005-07-27DALIAN UNIV OF TECH
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
DALIAN UNIV OF TECH
Publication Date
2005-07-27
Estimated Expiration
Not applicable · inactive patent

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Abstract

A process for preparing the coated medicine layer on the scaffold of blood vessel includes such steps as washing said scaffold, drying, proportionally mixing medicine with polymer carrier to obtain coating, connecting the scaffold to ground, high-pressure atomizing of said coating electrically charging the atomized coating by electrostatic generator, adsorbing the charged coating onto surface of scaffold under the action of electric field and high pressure, drying and disinfecting. Its electrostatic spray apparatus is composed of power source, changeover valve, high-pressure pump, coating container, filtering, electrostatic generator and spray gun with nozzle connected to said electrostatic generator.
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Description

technical field

[0001] The present invention relates to a drug coating preparation method for a vascular stent and an electrostatic spraying device thereof, more precisely, an efficient drug coating method for preparing a vascular stent by electrostatic spraying and an electrostatic spraying device thereof, belonging to medical devices field. Background technique

[0002] In 1987, Sigwart (Sigwart U, et al. Intravascular stents to preventocclusion and restenosis after transluminal angioplasty. N Engl J Med, 1987, 316: 701) etc. implanted coronary stents into the human body for the first time, which provided a great deal for the treatment of coronary heart disease. good way. However, in-stent restenosis caused by vascular stent implantation largely limits its curative effect. The cause of restenosis is that blood vessels are damaged after being expanded by stents, which induces excessive proliferation of vascular smooth muscle cells and migrates to the intima, resulting in ...

Claims

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