Oral gatifloxacin disintegrant and its preparing process

A technology for oral disintegrating tablets and gatifloxacin, which is applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, and pill delivery, etc., to achieve the effects of good taste, rapid disintegration, and improved bioavailability
CN1857228AInactive Publication Date: 2006-11-08SHENYANG NO 1 PHARMA FACTORY DONGBEI PHARMA GRP
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SHENYANG NO 1 PHARMA FACTORY DONGBEI PHARMA GRP
Publication Date
2006-11-08
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention provides an oral gatifloxacin disintegrant and its preparation process. The oral gatifloxacin disintegrant contains gatifloxacin in 20-75 wt% and medicinal supplementary material in 25-80 wt%, and the medicinal supplementary material includes one or several of disintegrating agent, stuffing, wetting adhesive, lubricant and coating material. The preparation process of the oral gatifloxacin disintegrant includes coating medicine powder or medicine carrying micro pill and tabletting. The oral gatifloxacin disintegrant of the present invention has the advantages of fast medicine release, increased absorbing points and less local excitation on gastrointestinal tract and is suitable for taking without using water and by patient with dysphagia.
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Description

technical field

[0001] The invention belongs to the technical field of medicine, and relates to an oral dosage form of antibacterial drug gatifloxacin—gatifloxacin orally disintegrating tablet and a preparation method thereof. Background technique

[0002] Orally disintegrating tablet is a new drug preparation, the English name is "Orally disintegrating tables", the US FDA has approved this dosage form for marketing, the reason is: it is convenient for some people to take medicine, such as the elderly, children with difficulty swallowing or patients in special circumstances.

[0003] Definition of orally disintegrating tablet: A tablet that disintegrates or dissolves in the oral cavity without the need for water. It should meet the requirements of the technical quality standard: ①Disintegrate rapidly in the oral cavity, without gritty feeling, good taste, easy to swallow, and non-irritating to the oral mucosa. ②Establish a suitable measurement method and limit of disintegra...

Claims

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