miRNA396 AND GROWTH REGULATING FACTORS FOR CYST NEMATODE TOLERANCE IN PLANTS

a growth regulation factor and nematode technology, applied in the field ofmirna396, can solve the problems of poor understanding of the regulatory networks governing gene expression patterns in nematode-infected roots and particularly in the developing syncytium, difficult application, and high cost, so as to improve the performance and increase the root mass. , the effect of increasing the survival rate of the plan
US20120278929A1Inactive Publication Date: 2012-11-01IOWA STATE UNIV RES FOUND
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Patent Information

Authority / Receiving Office
US · United States
Current Assignee / Owner
IOWA STATE UNIV RES FOUND
Publication Date
2012-11-01
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention presents methods to alter the genetic composition of crop plants susceptible to nematode infection to improve tolerance to the same. Methods and compositions for modulating key pathways involved in the syncytial event of nematode infection and for preventing the cascade of differential gene expression caused by the same as disclosed. Applicants have found that the microRNA miR396 acts as a master switch of syncytial gene expression changes in plants after infection, and further that miR396 and certain growth regulating transcription factors (GRF) are connected through feedback interaction in syncytium initiation and maintenance.
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Description

CROSS-REFERENCE TO RELATED APPLICATIONS

[0001] This application claims priority under 35 U.S.C. §119 to provisional application Ser. No. 61 / 480,093 filed Apr. 28, 2011, herein incorporated by reference in its entirety.GRANT REFERENCE

[0002] This invention was made with government support under Contract No. 2008-35302-18824 awarded by USDA. The government has certain rights in the invention.FIELD OF THE INVENTION

[0003] The invention relates generally to the field of plant molecular biology.BACKGROUND OF THE INVENTION

[0004] Nematodes are a very large group of invertebrate animals generally referred to as roundworms, threadworms, eelworms, or nemas. Some nematodes are plant parasites and can feed on stems, buds, leaves, and in particular on roots. Cyst nematodes (principally Heterodera and Globodera spp.) are key pests of major crops. Cyst nematodes are known to infect tobacco, cereals, sugar beets, potato, rice, corn, soybeans and many other crops. Heterodera schachtii principally attacks s...

Claims

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