50 results about "Glucocorticoid Receptor Agonists" patented technology

This invention is directed to a method for treating an inflammatory condition, treating haematological and other malignancies, causing immunosuppression, or preventing or treating transplant rejection in man or other animals which comprises administering to a patient a compound that has the structure of Formula (I) or Formula (II) as defined below, or a pharmaceutically acceptable derivative thereof or pro-drug therefor, wherein R═NH₂, NHR¹, NHOR², NHNHR², NHCOR², and R¹═C_(1-4)alkyl, C_(3-6)cycloalkyl, C_n, where n=1-3, R₂=methyl, ethyl, R₃=alkyl, cycloalkyl, substituted alkyl, substituted cycloalkyl, aryl, heteroaryl, substituted aryl, or substituted hetrecoaryl; wherein R⁴, R⁵═C_(1-4)alkyl. Novel compounds according to Formula (III), wherein R⁶ and R⁷ are any of H, CH₃CO, CH₃CH₂CO, CH₃CH₂CH₂CO provided that R⁶ and R⁷ are not both H, or Formula (IV), wherein R⁵ and R⁹ are any of H, CH₃CO, CH₃CH₂CO or CH₃CH₂CH₂CO, having use in such methods, are also described.