The invention provides compounds of the formula (I) or a salt, solvate or N-
oxide thereof, wherein: R1 and R2 are the same or different and each is selected from
hydrogen, saturated C1-3 hydrocarbyl,
halogen and cyano; X is selected from C═O, C═S, C(═O)NH, C(═S)NH, C(═O)O, C(═O)S, C(═S)O and C(═S)S; R3 is selected from
aryl and heteroaryl groups each having from 5 to 12 ring members and being unsubstituted or substituted by one or more
substituent groups R10 as defined in the claims; R4 and R5 are the same or different and are selected from
hydrogen and methyl; or one of R4 and R5 is selected from
hydroxymethyl and ethyl and the other is
hydrogen; and R6 and R7 are the same or different and are selected from hydrogen and methyl. The compounds of the formula (I) hayed activity as p38 MAP
kinase and Taf
kinase inhibitors.