The invention discloses an extraction device of cosmetic fibroin solution. The extraction device comprises a shell, a screen plate, a vertical rod and a connecting plate, wherein the interior of the shell is connected with the screen plate in a sleeved mode, the vertical rod is fixedly connected with the right end of the upper surface of the shell, the connecting plate is fixedly connected with the top end of the vertical rod, and mounting mechanisms are installed on the left side and the right side of the lower surface of the screen plate correspondingly. According to the extraction device ofthe cosmetic fibroin solution, through cooperative use of sleeves, a transverse rod, a baffle, a first spring, a clamping ring and the like, after the transverse rod and the clamping ring are separated, the screen plate is convenient to disassemble and replace, so that the practicability of the whole mechanism is improved; through cooperative use of a motor, a coupler, a bearing, a threaded seat,a threaded rod and the like, silk is conveniently pressurized, the motor is used for providing power, time and labor are saved, and application and popularization are facilitated; and through cooperative use of a transverse plate, a protective shell, an ejector rod, a control valve, a second spring and the like, the control valve is opened for solution collection.