Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Method for preparing medical porous alumina based ceramic composite

A technology of porous alumina and composite materials, which is applied in the field of medical porous alumina-based ceramic composite materials, which can solve the problems of poor mechanical properties, affecting the combination of implant materials and surrounding tissues, and unfavorable bone cell adhesion.

Inactive Publication Date: 2013-05-01
SHANDONG UNIV
View PDF2 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The Chinese patent No. 200710043985.6 discloses a preparation method of hierarchical porous alumina nano-insulation material, which is based on biological template synthesis technology, using industrial and domestic waste poultry eggshell membrane as template material, the egg membrane in the precursor liquid aluminum After immersion optimization treatment in salt solution, then oxidized and burned, alumina nanomaterials are formed in situ under the action of biological templates; the prepared porous alumina materials have no biological activity and poor mechanical properties
The Chinese patent with application number 200810015104.4 discloses "an alumina-based bioactive composite material". Although it has good bioactivity and good mechanical properties, due to the high density of the material, it is not conducive to the attachment of bone cells. Affects the bonding of the implant material to the surrounding tissue

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Embodiment 1: Calcium fluoride, alumina, and diopside are prepared as raw materials according to the mass percentages of 1% calcium fluoride, 98% alumina, and 1% diopside. Alumina balls are used for mixing and ball milling, and the powder after ball milling passes through a 100-mesh sieve to obtain a mixed powder. Put the mixed powder into a graphite mold for compression molding, hot press sintering under a nitrogen atmosphere, the sintering temperature is 1450°C, the sintering pressure is 30MPa, the sintering time is 1 hour, and the heat preservation is 30 minutes. The prepared alumina-based medical ceramic composite has a Rockwell hardness (HRA) of 90.67, a flexural strength of 381.3 MPa, and a fracture toughness of 4.68 MPa m 1 / 2 . The sintered samples were cut into 3.3mm×4.3mm×36mm specimens with an internal microtome, and after rough grinding, fine grinding and polishing, they were cleaned ultrasonically. Then, put them into the prepared simulated body fluid resp...

Embodiment 2

[0014] Embodiment two: other is the same as embodiment one, and difference is that calcium fluoride, aluminum oxide, diopside prepare raw material by the mass percentage of calcium fluoride 4%, aluminum oxide 95%, diopside 1%. The Rockwell hardness (HRA) of the prepared alumina-based ceramic composite is 90.37, the flexural strength is 474.1MPa, and the fracture toughness is 4.67MPa m 1 / 2 . After testing, there are a large number of pores on the surface, and a large amount of hydroxycarbonate apatite deposits are formed on the surface of the sample soaked in simulated body fluid, and the composite material has good biological activity.

Embodiment 3

[0015] Embodiment three: other is the same as embodiment one, and difference is that calcium fluoride, aluminum oxide, diopside prepare raw material by the mass percentage of calcium fluoride 8%, aluminum oxide 90%, diopside 2%. The Vickers hardness HV of the prepared alumina-based bioceramic composite is 17.40GPa, the flexural strength is 446MPa, and the fracture toughness is 4.66MPa m 1 / 2 . After testing, there are a large number of pores on the surface. The samples soaked in simulated body fluids were analyzed by SEM, and the deposits formed on the surface were bone-like apatite-hydroxycarbonated apatite.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Bending strengthaaaaaaaaaa
Fracture toughnessaaaaaaaaaa
Bending strengthaaaaaaaaaa
Login to View More

Abstract

The invention belongs to the field of biological ceramic materials, and discloses a method for preparing a medical porous alumina based ceramic composite. The method comprises the steps that the following materials by mass percent: 1-8% of calcium fluoride, 90-98% of alumina and 1-5% of diopside are prepared; calcium fluoride, alumina and the diopside are mixed and subjected to ball milling to form a mixed powder body; and then the mixed powder body is placed in a graphite jig for compression molding, subjected to hot pressed sintering in an argon or nitrogen atmosphere on the conditions that a sintering temperature is 1400 DEG C, a pressing temperature is 1320 DEG C, and sintering pressure is 30MPa, and subjected to temperature maintaining and pressure maintaining at 1400 DEG C for 30min. The composite prepared by the method has good mechanical property and bioactivity, and the surface of the composite is distributed with micropores, so that growth of a bone tissue is better facilitated. In addition, the method is low in production cost, and has better application prospects in repairing and replacing a bone of a human body.

Description

[0001] This application is a divisional application of the patent application No. 2010100114409. Technical field: [0002] The invention belongs to the field of bioceramic materials, in particular to a method for preparing a medical porous alumina-based ceramic composite material with high mechanical properties and good biological activity. Background technique: [0003] Alumina ceramic materials have the advantages of high hardness, wear resistance, heat resistance and chemical stability, and are one of the most widely studied ceramic materials at present. However, alumina is an inert ceramic material. As a repair material such as artificial joints, pure alumina cannot form osseointegration with body tissues because it has no biological activity. At present, hydroxyapatite ceramics are the most researched bioactive ceramics, which can form chemical bonds with tissues at the interface; however, pure hydroxyapatite ceramics are brittle and easy to break, which limits their wi...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C04B38/00C04B35/10
Inventor 张希华张木蕃
Owner SHANDONG UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com