Oxidation method of acetophenone

A technology of acetophenone and oxidant, applied in chemical instruments and methods, organic chemistry, molecular sieve catalysts, etc., can solve problems such as complex production process and harmful emissions, and achieve the effect of overcoming complex production process

Active Publication Date: 2013-07-17
CHINA PETROLEUM & CHEM CORP +1
View PDF7 Cites 22 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] Compared with the traditional method, the method provided by the present invention overcomes the problems of complex traditional production process, equipment corrosion, and harmful emissions,

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Oxidation method of acetophenone
  • Oxidation method of acetophenone

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] With acetophenone, hydrogen peroxide, solvent and catalyst (the mol ratio of zinc nitrate and titanium silicon molecular sieve 0.2: 1) according to acetophenone and hydrogen peroxide mol ratio is 1: 10, solvent acetonitrile and catalyst mass ratio are 20: 1. The mass ratio of acetophenone to catalyst is 10:1, and the reaction is carried out at a temperature of 50° C. and a pressure of 1.5 MPa. After 2 hours of reaction, the conversion rate of acetophenone was 83%; the selectivity of phenyl acetate was 66%.

Embodiment 2

[0035] Acetophenone, hydrogen peroxide, solvent and catalyst (the molar ratio of zinc phosphate and titanium silicon molecular sieve 1: 1) is 1: 6 according to the molar ratio of acetophenone and hydrogen peroxide, and the mass ratio of solvent acetone and catalyst is 50: 1. The mass ratio of acetophenone to catalyst is 20:1, and the reaction is carried out at a temperature of 60° C. and a pressure of 2.5 MPa. After 2 hours of reaction, the conversion rate of acetophenone was 59%; the selectivity of phenyl acetate was 68%.

Embodiment 3

[0037]With acetophenone, hydrogen peroxide, solvent and catalyst (the mol ratio of zinc sulfate and titanium silicon molecular sieve 0.1: 1) according to acetophenone and hydrogen peroxide mol ratio is 2: 11, solvent acetic acid and catalyst mass ratio are 60: 1. The mass ratio of acetophenone to catalyst is 1:1, and the reaction is carried out at a temperature of 100° C. and a pressure of 0.5 MPa. After 2 hours of reaction, the conversion rate of acetophenone was 56%; the selectivity of phenyl acetate was 70%.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses an oxidation method of acetophenone. According to the method, under oxidation reaction conditions, acetophenone, an oxidant, a solvent and a catalyst are mixed and subjected to a contact reaction. The method is characterized in that the catalyst is a soluble zinc salt modified heteroatom molecular sieve.

Description

technical field [0001] The present invention relates to an oxidation method of acetophenone, and furthermore relates to a method for preparing phenyl acetate by catalytic oxidation of acetophenone. Background technique [0002] Phenyl acetate is a colorless liquid with a boiling point of 195.7°C, a relative density of 1.0780, a refractive index of 1.5033 and a flash point of 76°C. Miscible with ethanol, ether, chloroform and acetic acid, slightly soluble in water. A strong refraction, phenol smell. It is mainly used as a solvent and an intermediate in organic synthesis. Phenyl acetate can also be used to obtain oxyacetophenone through transposition reaction, which can be used to treat acute and chronic icteric hepatitis, cholecystitis and other diseases. [0003] At present, the industrial production of phenyl acetate is mainly obtained by the reaction of sodium phenate and acetic anhydride. One operation method is to add phenol into sodium hydroxide solution, stir and di...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): C07C69/157C07C67/42B01J29/00B01J29/89
Inventor 林民史春风朱斌
Owner CHINA PETROLEUM & CHEM CORP
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap