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Traditional Chinese medicine composition for preventing and treating obese type 2 diabetes combined dyslipidemia

A technology for type 2 diabetes and dyslipidemia, applied in drug combinations, metabolic diseases, pharmaceutical formulations, etc., can solve problems that are difficult to achieve multi-target and personalized treatment, and achieve the goal of improving islet β-cell function and insulin resistance Effect

Active Publication Date: 2013-12-04
北京诺德康泽医院管理有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although improving glucose metabolism or lipid metabolism or losing weight can improve insulin resistance to a certain extent, since metabolic syndrome is not a single lesion, it is the interaction of multiple metabolic disorders such as glucose metabolism, lipid metabolism, hypertension, and high uric acid. Mutual aggravation, with insulin resistance as the soil, the result of joint action. At the same time, due to the characteristics of chemical drugs, it is difficult to achieve the goal of multi-target and personalized treatment. The treatment method needs to be further explored

Method used

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  • Traditional Chinese medicine composition for preventing and treating obese type 2 diabetes combined dyslipidemia
  • Traditional Chinese medicine composition for preventing and treating obese type 2 diabetes combined dyslipidemia
  • Traditional Chinese medicine composition for preventing and treating obese type 2 diabetes combined dyslipidemia

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0210] According to the arrangements in Table 20, the inventors conducted animal and / or human clinical experiments on the Chinese medicine composition of the present invention, and the results proved that each group of Chinese medicine compositions had significant therapeutic effects on obesity type 2 diabetes complicated with dyslipidemia (including different syndrome types) . According to different experimental requirements, each group of drugs also adopts different preparation forms when used, including water decoction, water extraction concentrated extract, non-decoction granules, granules prepared by conventional preparation technology, water pills, tablets etc.; and the dosage form itself has no effect on the effect of the drug.

[0211] Table 20 Experimental scheme for verifying the effect of Jiangtang and Lipid Recipe

[0212]

Embodiment 2

[0214] Typical cases:

[0215] Zhang, male, 39 years old, first visit, 2012-4-19, the patient suffered from diabetes for 1 year, did not receive regular treatment, did not take any hypoglycemic drugs, usually diet and exercise control, blood sugar control is not good now, in order to seek Chinese medicine treatment Come to see. Immediate symptoms: Occasional swelling and discomfort, slightly dry mouth, bitter mouth, occasional overeating and easy hunger, often tinnitus, pale red tongue, thin white fur, rapid pulse. Previously suffered from hypertension for 5 years, severe fatty liver for 7 years, and 9 years after boil removal. Current drugs: Amlodipine Besylate Controlled Release Tablets, 1#, Qd; Valsartan Capsules, 1#, Qd; Betaloc, 12.5mg, Qd; Bisoprolol Fumarate Tablets, 1#, Qd. 2012-4-19 Physical examination: height 168cm, weight 97kg, waist circumference 122cm, hip circumference 116cm. Laboratory tests: glycosylated hemoglobin (HbA1c) 8.6%, fasting blood glucose (...

Embodiment 3

[0226] Typical case 2:

[0227] Yan, female, 60 years old, first visit, 2012-2-3, the patient suffered from diabetes for 3 years, did not receive regular treatment, did not take any hypoglycemic drugs, usually diet and exercise control, blood sugar control is not good now, in order to seek Chinese medicine treatment Come to see. Immediate symptoms: slight distension of the chest, abdomen and abdomen, intermittently on and off, does not affect work and rest, occasional swelling and discomfort, dry mouth, can be relieved by a small amount of diet, poor sleep, back pain, chest pain, tongue Red and yellow coating, strong pulse. Previously suffered from coronary heart disease for 1 year. Current drugs: trimetazidine hydrochloride tablets, 20mg, tid; isosorbide mononitrate, 20mg, bid; bisoprolol, 2.5mg, Qd; aspirin, 100mg, Qd. 2012-2-2 Physical examination: height 158cm, weight 58.8kg, waist circumference 86cm, hip circumference 97cm. Laboratory tests: glycosylated hemoglobin (H...

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Abstract

The invention discloses a traditional Chinese medicine composition for preventing and treating obese type 2 diabetes combined dyslipidemia, belongs to the technical field of traditional Chinese medicine. The traditional Chinese medicine composition is made, by weight ratio, from coptis chinensis, bitter gourds, rhizoma anemarrhenae, aloe, red yeast rice, schisandra chinensis, rhizoma zingiberis, salvia miltiorrhiza and other crude drugs, and gastrodia elata, uncaria, gynostemma pentaphylla, radix polygoni multiflori preparata, raw rhubarb, magnolia officinalis, radices trichosanthis, scutellaria baicalensis and other crude drugs can be further added into the traditional Chinese medicine composition when necessary. The traditional Chinese medicine composition has a significant therapeutic effect on obese type 2 diabetes combined dyslipidemia.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for preventing and treating obesity type 2 diabetes combined with dyslipidemia, and belongs to the technical field of traditional Chinese medicines. Background technique [0002] With the development of society, the advancement of economic level and science and technology, the aging of the population and the change of lifestyle, the corresponding disease spectrum has also undergone tremendous changes, and there are more and more chronic diseases, whether in developed countries or developing countries In the country, the incidence of diabetes is getting higher and higher, and its disability rate and fatality rate have become the third serious chronic non-communicable disease after tumor and cardiovascular disease. Several large-scale national epidemiological surveys have shown that the incidence of diabetes in my country is in...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61P3/04A61P3/10A61P3/06A61P3/00
Inventor 仝小林
Owner 北京诺德康泽医院管理有限公司
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