Method for treating antibiotic dregs by adopting thermophilic microbial agent

A thermophilic microorganism and antibiotic technology, applied in the field of biodegradation, to achieve the effect of high reduction, low investment cost and small footprint

Active Publication Date: 2014-04-02
北京绿源科创环境技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The cost of incineration of fungal residues has become a bottleneck for the survival and development of the antibiotic industry

Method used

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  • Method for treating antibiotic dregs by adopting thermophilic microbial agent
  • Method for treating antibiotic dregs by adopting thermophilic microbial agent
  • Method for treating antibiotic dregs by adopting thermophilic microbial agent

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Embodiment 1 is used for processing the thermophilic microbial composite bacterial agent of antibiotic scum and its preparation

[0028] The active ingredients in the composite microbial agent include Geobacillus sp. UTM01 with a preservation number of CGMCC No.5641, Geobacillus sp. UTM02 with a preservation number of CGMCC No.5642, and Bacillus sp. UTM03 with CGMCC No.5643, Bacillus methylotrophicus UTM401 with CGMCC No.5927, Anoxybacillus sp. with CGMCC No.5928 mongoliensis) UTM501 and thermophilic facultative bacillus (Anoxybacillus pushchinoensis) UTM601 with the preservation number CGMCC No.5929, both of which are microorganisms screened from high temperature environments.

[0029] The number of viable bacteria in the thermophilic microbial compound bacterial agent is ≥1×10 11 CFU / mL.

[0030] Slant medium: 10g peptone, 10g yeast extract, 10g sodium chloride, 16-20g agar, 1000mL water, natural pH.

[0031] Seed medium: peptone 10g, yeast extract 10g, sodium chlori...

Embodiment 2

[0036] The processing of embodiment 2 cephalosporin slag

[0037] 40 tons of cephalosporin C (CPC) fungus residue was shipped from a company, with a water content of about 75%, of which about 42.9 crude protein, 2.9 crude fat, 38.1 sugar, 3.5 crude fiber and 3.5 crude fiber per gram of dry weight (%) Ash powder 8.7; Among them, calcium 2.2, phosphorus 1.3; amino acid content see Table 1. The cephalosporin content was 2414ppm. Add 20 tons of moisture regulator (water content about 30%), mix well, and the water content of this material is about 60%. Add 40L of the thermophilic microbial bacterial agent prepared in Example 1 and further mix evenly. Stack aerobic fermentation in the fermenter. On the 1st to 3rd day, the ventilation volume is low, the full volume is 700m 3 1 / 3 to 1 / 4 of the air volume per hour, increase the air volume to 1 / 2 to 1 of the full volume after the 4th day, and the full volume to the end of fermentation after 8 days.

[0038] Detect the temperature o...

Embodiment 3

[0044] The processing of embodiment 3 oxytetracycline slag

[0045] 21 tons of oxytetracycline fungus residues were shipped from a certain company, with a water content of about 72%, of which each g dry weight (%) contained about 44.7 crude protein, 1.1 crude fat, 36.2 sugar, 4.3 crude fiber, and 10.1 coarse ash; Among them, calcium 5.2, phosphorus 0.3; amino acid content is shown in Table 3. The content of oxytetracycline in oxytetracycline bacteria residue is 1103ppm. Add 10 tons of moisture regulator (water content about 30%), mix well, and the water content of this material is about 58%. Add 21L of the thermophilic microbial bacterial agent prepared in Example 1 and then further mix evenly. Use a forklift to transport to the fermentation tank for stacking aerobic fermentation. On the 1st to 4th day of aerobic fermentation, the ventilation rate is as low as 700m 3 1 / 3 to 1 / 4 of the / h, increase the air volume to 1 / 2 to 1 of the full amount after the 5th day, and increas...

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Abstract

The invention provides a method for treating antibiotic dregs by adopting a thermophilic microbial agent. The thermophilic microbial agent is added into the antibiotic dregs, so that the antibiotic dregs are reduced, and the antibiotic residues in the dregs are reduced. Under an aerobic fermenting condition, the antibiotic dregs are reduced by over 85%, and the removal rate of the antibiotic residues in the dregs reaches over 90%. The method has the advantages that the degree of reducing the antibiotic dregs is high, and the residue removal rate is high. The reduced dregs are then incinerated, so that the incinerating cost is greatly saved. The method is simple, easy to operate, small in occupied area, low in investment cost and free from secondary pollution to the environment, and has the remarkable economical, social and environment-friendly benefits.

Description

technical field [0001] The invention belongs to the field of biodegradation, and in particular relates to a method for treating antibiotic residues with a thermophilic microbial bacterial agent. Background technique [0002] Antibiotics play a huge role in human survival and development and animal husbandry production. So far, antibiotics are still unable to be replaced by other substances in their application fields. Antibiotic residue is an inevitable product of the antibiotic production process. These fungus residues are rich in protein, polysaccharides, and amino acids. Before 2008, they had been processed by drying and processing techniques or used as feed, feed additives, or as fertilizers and raw materials for the production of compound fertilizers. However, because the antibiotic residue in the antibiotic residue is relatively high, for example, the residue of cephalosporin C in the residue is about 2-2.5 mg / g, the residue of penicillin in the residue is about 1-2 ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12N1/20B09B3/00C12R1/11
Inventor 刘永跃何璧梅许宜北汪涌
Owner 北京绿源科创环境技术有限公司
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