Chlorine dioxide effervescent tablet for killing barbier bacteria and fungi and preparation method thereof
A technology of chlorine dioxide and effervescent tablets, which is applied in the direction of antibacterial drugs, antifungal agents, and pharmaceutical formulations, etc. It can solve problems such as low conversion rate, fragile tablets turn into powder, and slow rate, so as to accelerate dissolution Process, bactericidal effect advantage, effect of bactericidal effect enhancement
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Embodiment 1
[0043] Tablets weighing 4 grams were prepared using the following formulation.
[0044] Raw material name (kg)
Raw material ratio
10
Sodium dichloroisocyanurate
5
3
32
4.5
PVP / VA64
3
39
3
Cetyl chloramine
0.5
[0045] First put the above-mentioned raw material components into the dryer to dry, raise the temperature to 90°C, and discharge the intermediate when the moisture content of the intermediate is controlled below 1%. Put it in a plastic lined bag bucket or an airtight plastic bucket for later use.
[0046] First add 10 kg of sodium chlorite to the mixer, then add 3 kg of sodium bicarbonate, 0.5 kg of cetylchloramine, 3 kg of magnesium sulfate, and 32 kg of sodium chloride and mix thoroughly for 10 to 20 minutes. Minutes later, add 5 kg of...
Embodiment 2
[0051] Tablets weighing 1 gram were prepared using the following formulation.
[0052] Raw material name (kg)
Raw material ratio
Sodium chlorite (80% content)
20
10
2
Sodium chloride
19
3
L-HPC
2.5
39
2
Cetyl chloramine
0.5
2
[0053] First put the above-mentioned raw material components into the desiccator to dry, raise the temperature to 90°C, and discharge the intermediate when the moisture content of the intermediate is controlled below 1%, and then crush and sieve through a pulverizer and a vibrating sieve, and put them into moisture-proof containers. Store in a plastic lined bag or an airtight plastic bucket.
[0054] First add 20 kilograms of sodium chlorite to the mixer, then add 2 kilograms of sodium bicarbonate, 0.5 kilogram...
Embodiment 3
[0059] Tablets weighing 4 grams were prepared with the following formulation;
[0060] Raw material name (kg)
Raw material ratio
Sodium chlorite (80% content)
6
3
magnesium sulfate
3
Sodium chloride
32
4
2.5
40
sodium bicarbonate
5
Cetyl chloramine
0.5
3
[0061] The formulation raw materials are made according to the preparation methods described in Implementation 1 and Implementation 2. After obtaining the combined raw materials for tablets, use a 20mm punch to compress tablets with a pressure of 60KN in a tablet press, and press them into tablets with a weight of 4 grams. Use a pure aluminum foil bag Or high-barrier anti-corrosion plastic bags for packaging.
[0062] 4 gram tablet is dropped into 4 liters of water, after 20 minutes, the concentra...
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