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Combination capable of improving gastric-intestinal functions and preparation method of combination

A composition and technology of gastrointestinal tract, applied in the field of composition for improving gastrointestinal function and its preparation, can solve problems such as dependence of patients, increase of stool volume, failure to repair gastrointestinal epithelial cells, etc., and achieve inhibition of gastric Mucosa injury, improvement of gastrointestinal function, and effect of protecting gastric mucosa

Active Publication Date: 2015-06-24
GUANGZHOU KOHEALA BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among them, salt laxatives can cause serious adverse reactions; stimulant laxatives often contain anthraquinones, and long-term use can cause colonic melena or laxative colon, causing smooth muscle atrophy and damage to the intestinal myenteric plexus, which in turn aggravates Constipation, reversible upon discontinuation; prokinetics and lubricating laxatives often make patients dependent
Although solvent-based laxatives and osmotic laxatives are relatively safe, they can effectively relieve gastrointestinal related diseases, increase stool volume, and enhance defecation, but they cannot repair damaged gastrointestinal epithelial cells.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0085] The preparation of embodiment 1 apple stem cell freeze-dried powder

[0086] 1. The formula of the culture medium:

[0087] 1.1 Induction medium: MS solid medium + NAA0.5mg / L + BA 2mg / L + CH 1mg / L, pH value is 6.0;

[0088] 1.2 Proliferation medium: MS liquid medium+2,4-D 2.0mg / L+BA 1.0mg / L+CH1.0mg / L+AC 1.0mg / L, pH value is 6.0;

[0089] 2. Sterilization of apple branches

[0090] Choose green-planted apple trees free of chemical fertilizer and pesticide pollution, and select 10 10cm-long new shoots according to certain criteria; wash the surface attachments on the new shoots with 2L of sterile water; soak the new shoots in 120mg / L L-ascorbic acid 1 minute; sterilize new shoots in 75% ethanol solution for 1 minute, rinse with 2L sterile water; put them in 30% hydrogen peroxide solution for sterilization for 20 minutes, and rinse with sterile water for 10 minutes.

[0091] 3. Induction of cambium tissue

[0092] Use an inoculation knife to peel off the cambium, phloe...

Embodiment 2

[0101] Embodiment 2 Preparation of compositions for improving gastrointestinal function

[0102] First, 100 g of apple stem cell powder and 100 g of fructo-oligosaccharide are crushed and passed through a 100-mesh sieve, and then the crushed and sieved material is mixed with 300 g of polydextrose in a mixer evenly.

Embodiment 3

[0103] Embodiment 3 Preparation of composition for improving gastrointestinal function

[0104] First, 300 g of apple stem cell powder and 300 g of fructooligosaccharide are crushed and sieved through 100 sieves, and then the crushed and sieved materials are mixed with 400 g of polydextrose in a mixer evenly.

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PUM

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Abstract

The invention relates to the field of health care products, in particular to a combination capable of improving gastric-intestinal functions and a preparation method of the combination. The combination includes apple stem cell freeze-dried powder, fructo-oligosaccharide and polydextrose; experiments show that the combination can protect gastric mucosa of small mice and inhibit injury to the gastric mucosa of the small mice, and that effect that the ulceration index dropping to 23.94 to 25.69 from 62.74 is obviously higher than separate use of components. In addition, the experiments show that the combination can promote gastric-intestinal peristalsis of the small mice and bowel movement, small-intestine propelling rate rises to 67.48 to 69.03 from 54.86, and the function in promoting the gastric-intestinal peristalsis is obvious. In addition, remarkable effective rate among 306 patients with poor gastric-intestinal functions is 91.2%, which is obviously better than the efficiency in separate use of the components.

Description

technical field [0001] The invention relates to the field of health products, in particular to a composition for improving gastrointestinal function and a preparation method thereof. Background technique [0002] With the aging of the social population, changes in the pace of modern life and eating habits, etc., the incidence of constipation has increased significantly. The survey results show that the prevalence of constipation in the population is as high as 27%. Constipation is mainly manifested as: less desire to defecate, less frequent defecation; Accompanied by abdominal pain or discomfort. Some patients are also accompanied by mental and psychological disorders such as insomnia, irritability, dreaminess, depression, and anxiety. Constipation can affect people of all ages. Women are more than men, and the elderly are more than young and middle-aged. Constipation not only seriously affects the quality of life of modern people, but also is closely related to the inci...

Claims

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Application Information

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IPC IPC(8): A23L1/30A61K36/73A23L3/3544C12N5/04A61P1/00A61P1/04A23L33/10A23L33/125
CPCA23V2002/00A61K9/0056A61K9/0095A61K9/2054A61K9/2059A61K9/485A61K31/702A61K31/716A61K36/73A61K47/26A23V2200/32A23V2250/28A23V2250/5042A61K2300/00
Inventor 陈海佳王一飞葛啸虎戴国胜程建强
Owner GUANGZHOU KOHEALA BIOTECHNOLOGY CO LTD
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