Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Traditional Chinese medicine composition for treating osteoporosis and preparing method of traditional Chinese medicine composition

A technology for osteoporosis and composition, applied in the directions of drug combination, pharmaceutical formula, active ingredient of hydroxyl compounds, etc., can solve the problems of high price, uncertain long-term efficacy, and difficult to lasting efficacy.

Inactive Publication Date: 2016-01-06
王栩
View PDF4 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Although western medicines for treating osteoporosis have their own characteristics, they also have many toxic and side effects, high price, uncertain long-term curative effect, long time of taking medicine, and easy to cause a series of adverse reactions such as nervous system and digestive system. Disadvantages such as damage to organs such as the liver
For example, the side effects of hormone methods are relatively large, and there are short-term adverse reactions, such as vaginal bleeding, breast tenderness, and upper gastrointestinal symptoms; short-term use of estrogen replacement therapy is difficult to achieve long-term efficacy, and long-term use is likely to lead to various complications (such as breast cancer, intrauterine Membrane cancer, etc.); most calcium preparations are poorly absorbed or calcium and phosphorus cannot be deposited in bones after absorption; bisphosphonates may cause digestive tract discomfort, proteinuria, fever, bone mineralization disorders, etc.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Traditional Chinese medicine composition for treating osteoporosis and preparing method of traditional Chinese medicine composition
  • Traditional Chinese medicine composition for treating osteoporosis and preparing method of traditional Chinese medicine composition
  • Traditional Chinese medicine composition for treating osteoporosis and preparing method of traditional Chinese medicine composition

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0044] The present invention also provides a preparation method of the above-mentioned traditional Chinese medicine composition, comprising:

[0045] (1) Mix the components in the raw material components in proportion, pulverize, add ethanol with an alcohol concentration of 80-90% relative to the mass of the mixture 3-5 times, heat and reflux for 1-3 hours, extract and filter Obtain the first extract, filter the obtained dregs, add ethanol with an alcohol concentration of 80-90% relative to the mass of the dregs, heat and reflux for 35-55 minutes, extract, filter to obtain the second extract, and The first extract and the second extract are combined, concentrated under reduced pressure to remove the ethanol solvent, and dried to obtain a dry paste;

[0046] (2) Place the dry paste obtained in (1) in an ultrafine pulverizer to pulverize for 1-2 hours, pulverize and sieve to obtain ultrafine powder of 200-400 mesh;

[0047] (3) Add 0.2-0.4 times of microcrystalline cellulose, 0...

Embodiment 1

[0052] Get 10 parts by weight of Achyranthes bidentata, 7 parts by weight of Ligustrum lucidum, 8 parts by weight of Alisma alisma, 8 parts by weight of oyster, 5 parts by weight of radish seed, 10 parts by weight of Aconiti, 12 parts by weight of Morinda officinalis, 5 parts by weight of psoralen , 4 parts by weight of corydalis, 5 parts by weight of borneol, 4 parts by weight of cicada slough, 6 parts by weight of Eucommia, 10 parts by weight of angelica, 4 parts by weight of dried blood, 5 parts by weight of dodder, mixed in proportion, crushed, and added 3 times the mass of the mixture The ethanol with an alcohol concentration of 80% is heated to reflux for 1 hour, extracted, filtered to obtain the first extract, and the dregs obtained by filtering are added with ethanol with an alcohol concentration of 1 times that of the dregs, and heated to reflux for 35 minutes , extract, filter to obtain the second extract, combine the first extract and the second extract, concentrate ...

Embodiment 2

[0056] Get 16 parts by weight of Achyranthes bidentata, 11 parts by weight of Ligustrum lucidum, 16 parts by weight of Alisma, 12 parts by weight of oysters, 9 parts by weight of radish, 16 parts by weight of Aconitum, 18 parts by weight of Morinda officinalis, and 10 parts by weight of psoralen , 8 parts by weight of corydalis, 11 parts by weight of borneol, 8 parts by weight of cicada slough, 10 parts by weight of Eucommia sinensis, 16 parts by weight of angelica, 8 parts by weight of dried blood, 11 parts by weight of dodder seed, mixed in proportion, crushed, and added 5 times the mass of the mixture The ethanol with an alcohol concentration of 90% was heated to reflux for 3 hours, extracted, filtered to obtain the first extract, and the dregs obtained by filtering were added with ethanol with an alcohol concentration 3 times that of the dregs, and heated to reflux for 55 minutes , extract, filter to obtain the second extract, combine the first extract and the second extrac...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a traditional Chinese medicine composition for treating osteoporosis. The traditional Chinese medicine composition comprises the following raw material ingredients including achyranthes bidentata, fructus ligustri lucidi, alisma plantago-aquatica, oysters, semen raphani, radix aconiti, morinda officinalis, psoralea corylifolia, corydalis yanhusuo, borneol, cicada sloughs, eucommia ulmoides, angelica sinensis, daemonorops draco and cuscuta chinensis. The traditional Chinese medicine composition has the advantages that the osteoporosis index can be effectively reduced; the clinical sign of a patient is reduced; the further exacerbation of the osteoporosis is prevented; meanwhile, no toxic or side effect exists; and high safety and high comfort are realized.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating osteoporosis and a preparation method thereof. Background technique [0002] Osteoporosis is a systemic skeletal disease characterized by decreased bone tissue content per unit volume, decreased bone density, and weakened bone strength, resulting in increased bone structure and bone fragility and prone to fractures. It is a common and frequently-occurring disease in orthopedics. The clinical manifestations mainly include decreased bone mineral content, changes in the fine structure of the bone, decreased bone toughness, and fractures can occur after minor trauma, which illustrates the nature, pathological changes and serious consequences of osteoporosis. [0003] Osteoporosis is divided into primary and secondary osteoporosis: primary osteoporosis is divided into two types related to menopause estrogen d...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/889A61K36/896A61P19/10A61K31/045A61K35/618A61K35/64
Inventor 不公告发明人
Owner 王栩
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products