Hybrid intestinal micro-ecologic preparation and preparation method thereof

Abstract

The invention provides a hybrid intestinal micro-ecologic preparation and a preparation method thereof. The preparation method comprises the following steps: carrying out third-stage fermentation culture on probiotics butyric acid bacteria, lactobacillus acidophilus, Bacillus coagulans and Bacillus licheniformis, adding a freeze drying protection gent, freeze-drying the obtained culture product, carrying out microcapsule embedding, freeze-drying the embedded product, and mixing the embedded product with isomaltooligosacharide, fructooligosaccharide and vitamins to obtain the micro-ecologic preparation. Butyric acid bacteria and other probiotics can be directly supplemented to the human body intestinal tract, so all the probiotics are propagated and intergrow in the intestinal tract and have synergism, and the intestine controlling, cancer preventing, immunity improving, digestion helping and harmful bacterium and corrupted group growth breeding inhibiting effects of the composite bacterium preparation are effectively performed, thereby the beneficial physiologic effects of the probiotics on human bodies are greatly improved; and the preparation method can effectively guarantee the quantity of live bacteria of the probiotics, the activity of the probiotics and the preservation time of the probiotics.

Description

technical field [0001] The patent of the present invention belongs to the category of microecological preparations, and specifically relates to a mixed intestinal microecological preparation and a preparation method thereof. Background technique [0002] There are more than 400 species and tens of trillions of bacteria living in the intestinal tract of healthy people. These microorganisms participate in the physiological, growth, biophysical, pharmacological and pathological processes of all life activities of the human body. According to the effect on the human body, we divide these bacteria into beneficial bacteria, harmful bacteria and bidirectional bacteria. These bacteria are interdependent and restrict each other, and are in a relatively balanced state, forming the largest micro-ecological environment in the body, becoming a natural line of defense to maintain human health, and jointly completing the functions of nutrient absorption and toxin excretion. It plays an ex...

AI Technical Summary

Problems solved by technology

However, these probiotics have a fatal weakness. During transportation, storage and application, these unprotected active microorganisms need to withstand a series of adverse environments (such as aerobic state, high temperature, extrusion, low pH, high Bile salts, etc.) can reach colonization in the intestinal tract. In this process, due to the poor oxygen resistance, acid resistance and high temperature resistance of some anaerobic bacteria or facultative anaerobic bacteria and other special bacteria, poor stress resistance, intolerance Stomach acid and bile salts are easily affected by various external biochemical and physical factors, resulting in greatly reduced activity or even death. It is difficult to have sufficient quantities to reach the intestinal tract or settle in the intestinal tract to play a role, which seriously affects the potency of live bacterial preparations

The number of live bacteria in the current microecological preparations is low (less than 300 million per gram), and the number of live bacteria in probiotics decreases with the increase of storage time after preparation (the number of live bacteria in 1.5 years is only the 50%-55% of the original), in addition, the current probiotics use a single strain of bacteria, so their therapeutic and health effects are limited