Granules for regulating and stabilizing hypertensive nephrosclerosis and preparation method of granules
A technology for hypertensive nephropathy and granules, which is applied in the field of granules for regulating and stabilizing hypertensive nephropathy and its preparation, can solve problems such as renal arteriolar stenosis, aggravated renal function damage, and cell structure destruction, and achieve accelerated drug recovery. Response, reduce kidney damage, kidney tonifying effect
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Embodiment 1
[0020] Embodiment 1: A granule for regulating and stabilizing hypertensive nephropathy, comprising the following components by weight: 14.3 parts of gallic acid, 12.7 parts of hyperoside, 11.6 parts of scopolamine, 10.3 parts of sennoside, Gastrodia elata 9.8 parts of polysaccharide, 8.1 parts of ursolic acid, 7.2 parts of emodin, 6.5 parts of arabinose, 5.2 parts of quercetin, 4.3 parts of Prunella vulgaris extract, 3.9 parts of β-sitosterol, 0.4 parts of amlodipine, 0.2 parts of hydrochlorothiazide, 0.9 parts of rutin, 0.008 parts of vitamin H, 0.005 parts of vitamin B, 0.003 parts of vitamin C, 65 parts of thinner, 39 parts of binder, 11 parts of disintegrant, 2 parts of lubricant, 2.5 parts of surfactant .
[0021] Wherein, the extraction method of Gastrodia elata polysaccharide is as follows: take the dried tubers of Gastrodia elata, cut them into small pieces, place them in a dryer to dry, set the drying temperature to 40°C, and make the moisture content lower than 8%. ...
Embodiment 2
[0026] Embodiment 2: A granule for regulating and stabilizing hypertensive nephropathy, comprising the following ingredients in parts by weight: 25 parts of gallic acid, 22.4 parts of hyperoside, 20.9 parts of scopolamine, 19.4 parts of sennoside, Gastrodia elata 18.6 parts of polysaccharide, 16.7 parts of ursolic acid, 15.5 parts of emodin, 14.2 parts of arabinose, 12.5 parts of quercetin, 10.7 parts of Prunella vulgaris extract, 9.9 parts of β-sitosterol, 0.6 parts of amlodipine, 0.4 parts of hydrochlorothiazide, 1.6 parts of rutin, 0.014 parts of vitamin H, 0.011 parts of vitamin B, 0.007 parts of vitamin C, 107 parts of diluent, 70 parts of binder, 21.5 parts of disintegrant, 3.5 parts of lubricant, 4.6 parts of surfactant .
[0027] Wherein, the extraction method of Gastrodia elata polysaccharide is as follows: take the dried tubers of Gastrodia elata, cut into small pieces, place them in a dryer to dry, set the drying temperature to 45°C, and make the moisture content lo...
Embodiment 3
[0032] Embodiment 3: A granule for regulating and stabilizing hypertensive nephropathy, comprising the following ingredients in parts by weight: 35.7 parts of gallic acid, 32.1 parts of hyperoside, 30.2 parts of scopolamine, 28.5 parts of sennoside, Gastrodia elata 27.4 parts of polysaccharide, 25.3 parts of ursolic acid, 23.8 parts of emodin, 21.9 parts of arabinose, 19.8 parts of quercetin, 17.1 parts of Prunella vulgaris extract, 15.9 parts of β-sitosterol, 0.8 parts of amlodipine, 0.6 parts of hydrochlorothiazide, 2.3 parts of rutin, 0.02 parts of vitamin H, 0.017 parts of vitamin B, 0.011 parts of vitamin C, 149 parts of diluent, 101 parts of binder, 32 parts of disintegrant, 5 parts of lubricant, 6.7 parts of surfactant .
[0033] Wherein, the extraction method of Gastrodia elata polysaccharide is as follows: take the dried tubers of Gastrodia elata, cut them into small pieces, place them in a dryer to dry, set the drying temperature to 50°C, and make the moisture conten...
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