Granules for regulating and stabilizing hypertensive nephrosclerosis and preparation method of granules

A technology for hypertensive nephropathy and granules, which is applied in the field of granules for regulating and stabilizing hypertensive nephropathy and its preparation, can solve problems such as renal arteriolar stenosis, aggravated renal function damage, and cell structure destruction, and achieve accelerated drug recovery. Response, reduce kidney damage, kidney tonifying effect

Inactive Publication Date: 2016-07-20
徐忠琴
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Hypertensive nephropathy will cause the patient's kidney detoxification burden to be too heavy, resulting in aggravated renal function damage, resulting in decreased renal function. Due to the large amount of toxins in the body stimulating the reduction of red blood cell production, anemia is caused. In addition, hypertensive nephropathy is stimulated by long-term high blood pressure. The long-term pressure on the arterial wall is too high, and th

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0020] Example 1: A granule for conditioning and stabilizing hypertensive nephropathy, comprising the following components by weight: 14.3 parts of gallic acid, 12.7 parts of hyperoside, 11.6 parts of scopolamine, 10.3 parts of sennoside, and Gastrodia Polysaccharides 9.8 parts, ursolic acid 8.1 parts, emodin 7.2 parts, arabinose 6.5 parts, quercetin 5.2 parts, prunella vulgaris extract 4.3 parts, β-sitosterol 3.9 parts, amlodipine 0.4 parts, hydrochlorothiazide 0.2 parts, 0.9 parts of rutin, 0.008 parts of vitamin H, 20.005 parts of vitamin B, 0.003 parts of vitamin C, 65 parts of diluent, 39 parts of binder, 11 parts of disintegrant, 2 parts of lubricant, 2.5 parts of surfactant .

[0021] Wherein, the method for extracting the gastrodia elata polysaccharide is: take the dried gastrodia elata tubers, cut into small pieces, dry them in a dryer, set the drying temperature to 40°C, and make the moisture content less than 8%, and then Add 38 times the amount of water and place it ...

Example Embodiment

[0026] Example 2: A granule for conditioning and stabilizing hypertensive nephropathy, comprising the following ingredients in parts by weight: 25 parts of gallic acid, 22.4 parts of hyperoside, 20.9 parts of scopolamine, 19.4 parts of sennoside, and Gastrodia Polysaccharides 18.6 parts, ursolic acid 16.7 parts, emodin 15.5 parts, arabinose 14.2 parts, quercetin 12.5 parts, prunella vulgaris extract 10.7 parts, β-sitosterol 9.9 parts, amlodipine 0.6 parts, hydrochlorothiazide 0.4 parts, 1.6 parts of rutin, 0.014 parts of vitamin H, 20.011 parts of vitamin B, 0.007 parts of vitamin C, 107 parts of diluent, 70 parts of binder, 21.5 parts of disintegrant, 3.5 parts of lubricant, 4.6 parts of surfactant .

[0027] Wherein, the method for extracting the polysaccharides of Gastrodia elata is: take the dried tubers of Gastrodia elata, cut into small pieces, and place them in a dryer for drying. Set the drying temperature to 45°C and make the moisture content less than 8%. Add 38 times ...

Example Embodiment

[0032] Example 3: A granule for conditioning and stabilizing hypertensive nephropathy, comprising the following components by weight: 35.7 parts of gallic acid, 32.1 parts of hyperoside, 30.2 parts of scopolamine, 28.5 parts of sennoside, and Gastrodia Polysaccharides 27.4 parts, ursolic acid 25.3 parts, emodin 23.8 parts, arabinose 21.9 parts, quercetin 19.8 parts, prunella vulgaris extract 17.1 parts, β-sitosterol 15.9 parts, amlodipine 0.8 parts, hydrochlorothiazide 0.6 parts, 2.3 parts of rutin, 0.02 parts of vitamin H, 20.017 parts of vitamin B, 0.011 parts of vitamin C, 149 parts of diluent, 101 parts of binder, 32 parts of disintegrant, 5 parts of lubricant, 6.7 parts of surfactant .

[0033] Wherein, the method for extracting the polysaccharides of Gastrodia elata is: take the dried tubers of Gastrodia elata, cut into small pieces, dry them in a dryer, set the drying temperature to 50°C, and make the moisture content less than 8%. Add 38 times the amount of water and pla...

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PUM

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Abstract

The invention discloses granules for regulating and stabilizing hypertensive nephrosclerosis and a preparation method of the granules. The granules for regulating and stabilizing hypertensive nephrosclerosis are prepared from the following components: gallic acid, hyperoside, scopoletin, senna fructus, gastrodia elata polysaccharide, ursolic acid, rheum emodin, arabinose, quercetin, a selfheal extract, beta-sitosterol, amlodipine, hydrochlorothiazide, rutin, vitamin H, vitamin B2, vitamin C, a diluent, an adhesive, a disintegrating agent, a lubricating agent and a surfactant. The granules are used for regulating the hypertensive nephrosclerosis; due to multiple effects of reducing the pressure, assisting diuresis, resisting bacteria, relaxing bowels, tonifying and benefiting kidney and enhancing body resistance, the blood pressure can be stably controlled; furthermore, the body functions can be adjusted, and the symptoms can be controlled, so that harm to the kidney is reduced.

Description

technical field [0001] The invention relates to the field of nursing medication, in particular to a granule for regulating and stabilizing hypertensive nephropathy and a preparation method thereof. Background technique [0002] Hypertensive nephropathy is benign arteriolar nephrosclerosis and malignant arteriolar sclerosis caused by essential hypertension, accompanied by corresponding clinical manifestations of hypertension and renal failure. The first symptom is often edema, followed by nocturia and urine concentration Decreased function, lighter urine specific gravity, mild proteinuria, microscopic hematuria and casts, often other target organ complications of hypertension. Hypertensive nephropathy will cause the patient's kidney detoxification burden to be too heavy, resulting in aggravated renal function damage, resulting in decreased renal function. Due to the large amount of toxins in the body stimulating the reduction of red blood cell production, anemia is caused. In...

Claims

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Application Information

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IPC IPC(8): A61K36/536A61K9/16A61P9/12A61P13/12A61K31/715A61K31/7048A61K31/704A61K31/7004A61K31/575A61K31/56A61K31/549A61K31/525A61K31/4422A61K31/4188A61K31/375A61K31/366A61K31/352A61K31/192A61K31/122
CPCA61K36/536A61K9/1652A61K31/122A61K31/192A61K31/352A61K31/366A61K31/375A61K31/4188A61K31/4422A61K31/525A61K31/549A61K31/56A61K31/575A61K31/7004A61K31/704A61K31/7048A61K31/715A61K2300/00
Inventor 徐忠琴陈静
Owner 徐忠琴
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