Modified bone cement

Abstract

The invention discloses modified bone cement. The modified bone cement is prepared from, by mass, 2-5 parts of phosphorus pentoxide, 10-12 parts of bioactive glass, 5-6 parts of polyvinyl chloride, 8-10 parts of microcrystal kaolinite clay, 4-6 parts of sodium hydrogen phosphate, 3-5 parts of polyvinyl alcohol, 4-5 parts of ferroferric oxide, 4-6 parts of potassium chloride, 50-55 parts of ammonium sulfate, 10-12 parts of silicon carbide whiskers, 6-8 parts of urea, 5-6 parts of graphite powder, 3-4 parts of sodium polyacrylate, 3-5 parts of polyvinylpyrrolidone, 4-5 parts of carrageenan, 5-8 parts of titanium dioxide, 3-4 parts of ethylparaben, 2-3 parts of 2-amino-2-methyl-1-propanol and 10-12 parts of deionized water. According to the modified bone cement, mechanical performance, antibacterial performance, water collapse resistance, injection performance and bio-compatibility are improved, the degradation rate of the bone cement can be controlled, the degradation rate is matched with the bone formation rate, it is guaranteed that alling or stripping of residues and powder is avoided during operation of the bone cement, no solid-liquid separation phenomenon exists, the process is easy and convenient, and the modified bone cement can be widely used for bio-materials.

Description

technical field [0001] The invention relates to the technical field of orthopedic materials, in particular to a modified bone cement. Background technique [0002] The traditional artificial bone needs to be prefabricated into a certain shape in vitro and then implanted into the human body for bone repair. This kind of operation is traumatic. Injectable artificial bone repairs bone defects with less trauma, and has obvious advantages in the repair of superficial, cystic and vertebral bone defects. It is attracting increasing attention and becoming the future development direction of artificial bones. Commonly used injectable materials include injectable calcium sulfate, calcium phosphate and compound preparations, organic materials, etc. [0003] As a traditional bone repair material, calcium sulfate has good application prospects in bone repair due to its good biocompatibility, injectability, and osteoconductivity. The curative effect and biological properties are more ac...

AI Technical Summary

Problems solved by technology

[0003] As a traditional bone repair material, calcium sulfate has good application prospects in bone repair due to its good biocompatibility, injectability, and osteoconductivity. The curative effect and biological properties are more accurate and stable, and it provides an effective way for minimally invasive treatment of bone defects; however, calcium sulfate bone cement also has shortcomings such as short injectable time and lack of osteoinductive activity

[0004] Calcium phosphate materials have good injectability, among which hydroxyapatite has good bioactivity and biocompatibility, can conduct bone growth, is gradually absorbed by tissues and produces bone tissue regeneration effect, but hydroxyapatite meets water Disadvantages such as easy collapse, reduced mechanical strength, and slow degradation rate limit its application to a certain extent.