A humectant for endoscope cleaning and a preparation method thereof

Abstract

A humectant for endoscope cleaning is disclosed. The humectant includes, by weight, 4-14 parts of a polyol compound, 0.1-2 parts of a borate compound, 0.5-5 parts of biological hydrolase, 0.1-2.0 parts of a surfactant and 50-200 parts of water. The surfactant is a mixture of at least one anionic surfactant and at least one nonionic surfactant. The humectant has capabilities of cleaning, moisture maintaining and disinfection pretreatment for endoscope biopsy pipelines, can rapidly and effectively decompose residual blood, gastrointestinal tract mucus and other organic matters in endoscope biopsy pipelines before drying up, and can prevent formation of bacterial biofilms. The humectant can effectively dissociate present bacterium biofilms already in the endoscope biopsy pipelines, kill mostpathogenic microorganisms, shorten cleaning and disinfection time of endoscopes, increase the recycle rate of the endoscopes and reduce the medical treatment cost.

Description

technical field [0001] The invention belongs to the field of cleaning supplies for medical instruments, and relates to a cleaning and moisturizing agent, in particular to an endoscope cleaning and moisturizing agent and a preparation method thereof. Background technique [0002] It is reported that 65% of clinical bacterial infections are caused by bacterial biofilms. With the gradual deepening of basic research on endoscopic bacterial biofilm, people pay more attention to how to prevent and remove endoscopic biofilm clinically as an important research and development direction. The modern point of view is that biofilm is an ecological community composed of microorganisms and extracellular polymers irreversibly combined with their surroundings. It often shows different phenotypes according to the growth rate of microorganisms and gene transcription. Biomaterial-related infections caused by biofilms are widely distributed in various clinical departments, including endoscopic...

AI Technical Summary

Problems solved by technology

[0003] 1. Due to the complex structure and expensive materials of the endoscope, it cannot be sterilized by high temperature and high pressure. The frequent use of endoscopes leads to too short chemical disinfection time to effectively kill all pathogenic microorganisms in the official cavity

[0004] 2. Many human factors make the endoscope cleaning and disinfection process not standardized, resulting in the failure of endoscope decontamination. The important factor is that the endoscope is not cleaned in time, resulting in residual blood, gastrointestinal mucus and other blood in the biopsy pipeline. The organic matter is extremely dry, which makes it easy for various bacteria to grow and multiply here, forming bacterial pockets, leading to the growth of bacterial biofilms

During this process, the residual blood, gastrointestinal mucus and other organic substances in the endoscopic biopsy tube, and the human secretions adhering to the instrument are denatured to produce fibrous membranes that adhere to the surface, making cleaning difficult, especially for various class gap

All kinds of bacteria grow and reproduce here, forming bacterial pockets, resulting in the formation of bacterial biofilm on the surface of the endoscope's pipeline. Once the biofilm is formed, it is almost impossible to completely remove the biofilm with conventional cleaning methods, resulting in disinfection or disinfection. The failure of sterilization leads to the occurrence of cross-infection, and nosocomial infection caused by incomplete cleaning and disinfection of endoscopes has become an important clinical problem at present.

At the same time, during the cleaning and disinfection operation time, the amount of cleaning agent is increased. These operations may cause scratches on the endoscope during cleaning, corrode the endoscope, and reduce the service life of the endoscope.

The high price caused by the extensive use of cleaning agents and endoscope replacement will lead to an increase in the medical expenses of the majority of patients

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