7 results about "Endoscopic biopsy" patented technology

The invention relates to the technical field of medical biopsy instruments, in particular to an endoscopic biopsy device for respiration and critical diseases, which comprises a catheter, a cylindrical sealing piston head is slidably mounted in the catheter, an up-down through vent hole is formed in the sealing piston head, and one end, positioned in vitro, of the catheter is connected with negative pressure; a branch pipe with the tail end sealed is further arranged at the end extending out of the body, a stay wire hole is formed in the center of the sealing piston head, and a stay wire is slidably installed in the stay wire hole. One end of the pull wire extends out of the branch pipe and is provided with a pull ring; one end, far away from the pull ring, of the pull wire is provided with an umbrella-shaped cutting head and a limiting ring; the bottom of the cutting head is provided with a circle of annular cutting edge, the annular cutting edge is located above the sealing piston head, the limiting ring is located below the cutting head, and the distance between the annular cutting edge and the cutting head is larger than the height of the sealing piston head. According to the scheme of combining negative pressure adsorption and mechanical cutting, the tissue sample size larger than that of traditional biopsy forceps can be obtained, and the requirements of pathological examination are effectively met.

The invention discloses a protein marker for differential diagnosis of intestinal extracorporeal natural killer / T cell lymphoma and application of the protein marker. The protein marker is composed of COL6A3 and MFAP2 protein. Or the protein is composed of ADAMTS4, COL6A3 and MFAP2 protein. The invention also provides application of a reagent for detecting the protein in preparation of a kit for diagnosing intestinal natural killer cell / T cell lymphoma or evaluating the occurrence risk of the intestinal natural killer cell / T cell lymphoma. According to the invention, the technical bottleneck of difficulty in pathological diagnosis caused by superficial endoscopic biopsy sample of the intestinal ENKTL is effectively solved, and ENKTL can be accurately identified from ulcerative colitis, diffuse large B-cell lymphoma and colon cancer. The method is simple and convenient to operate, the selected antibody is strong in signal and clear in background in IHC detection, a quantitative result with good repeatability and high specificity can be obtained by combining an H-score scoring system, and objectivity and accuracy of pathological diagnosis are remarkably improved.

The application discloses an endoscope biopsy guiding system and a control method. The system comprises an endoscope front-end probe assembly, an image processing host and an operation control terminal. The microscopic image acquisition unit in the endoscope front-end probe assembly is pre-aligned with the physical sampling path of the biopsy tool. The image processing host is configured to acquire a microscopic image, process and generate an evaluation signal representing the pathological value of the target tissue, judge whether the evaluation signal meets the preset trigger condition, and send an enable signal to the operation control terminal to drive the operation limiting unit to release the operation limitation of the sampling execution component when the condition is met. The method comprises corresponding image acquisition, evaluation signal generation, condition judgment and unlocking control steps. By constructing a "verify first and sample later" physical interlocking mechanism, the application can ensure that the sampling operation is only performed in the high pathological value area, effectively avoiding the misoperation caused by blind sampling, and significantly improving the accuracy of biopsy sampling and the positive rate of diagnosis.

The utility model discloses a digestive tract endoscopic biopsy pathological sample fixing box, which relates to the technical field of medical supplies, and comprises an embedding box base and an embedding box upper cover, the embedding box upper cover is covered on the embedding box base, a pathological number coding area is arranged above the front side of the embedding box base, and the embedding box upper cover is covered on the embedding box base. A groove is formed in the middle of the upper surface of the embedding box base, at least part of space in the groove forms a specimen fixing area, filter paper is arranged on the bottom wall and the circumferential side wall of the specimen fixing area, and a specimen recognition area is formed in the position, on the rear side of the specimen fixing area, above the embedding box base. And the upper surface of the embedding box base is provided with a two-dimensional code pasting area on the left side of the specimen recognition area. The specimen box has the advantage of preventing the specimen in the box from being lost and polluted by the outside.

The utility model discloses an endoscope biopsy hole one-way valve device which comprises a valve body, the valve body is provided with a filter layer, an isolation layer and a biopsy forceps moving opening, the filter layer is provided with a filter one-way opening, the isolation layer is provided with an isolation one-way opening, and the biopsy forceps moving opening is located on the side, away from the filter layer, of the isolation layer; the valve cover is detachably connected with the valve body, the valve cover is provided with a pressure relief opening, and the pressure relief opening is communicated with the biopsy forceps movable opening; the valve cover is provided with a clamping table which is matched with the valve body; the valve body is provided with a clamping groove, and the clamping table is matched with the clamping groove. The valve body is provided with a locking table which abuts against the clamping table. The valve cover is provided with a locking groove, and the locking table is matched with the locking groove; in the closed state, the clamping table is arranged in the clamping groove, and the locking table is arranged in the locking groove, and in the open state, the clamping table is far away from the clamping groove, and the locking table is far away from the locking groove. Through the arrangement of the filtering layer and the isolating layer, liquid or polluting gas and the like on the inner side can be effectively prevented from overflowing, the pollution risk is reduced, and the operation environment is kept clean.

The utility model belongs to the technical field of embedding molds, and particularly relates to an endoscope biopsy specimen embedding mold easy to continuously slice, which comprises an integrated base, the integrated base comprises a mold base, a plurality of embedding bins are arranged on two sides of the mold base, and detachable single molds are mounted above the embedding bins; the detachable single mold comprises an embedding frame, the embedding frame is installed above the mold base, an embedding cavity is formed in the middle of the bottom of the embedding frame, the embedding cavity is located on the inner side of the embedding bin, round top holes are formed in the two sides of the embedding frame, and demolding top columns are installed above the round top holes. According to the utility model, a plurality of detachable single molds can be integrated to form a plurality of embedding units, a gas-driven demolding support pillar is arranged below each embedding unit, and the gas-driven demolding support pillars move upwards to apply uniform lifting force to the embedding blocks, so that batch demolding of the embedding blocks in each embedding unit is completed; meanwhile, the embedding block is prevented from being damaged and deformed.

The pair of endoscope biopsy forceps comprises forceps heads and a forceps head seat, the forceps heads are oppositely arranged left and right, the tail ends of the forceps heads are hinged, the forceps head seat is cylindrical, a boss used for installing a cylindrical pin is arranged at the top of the forceps head seat, two shoulders of the boss form a guide edge, a first limiting surface is arranged on the outer side of a supporting arm at the tail of each forceps head, and a second limiting surface is arranged on the outer side of the supporting arm. The tong head is inserted from the top of the tong head seat, and when the first limiting face slides relative to the guide edge, the tong head is closed. The forcep head seat is cylindrical, the limiting surface is arranged outside the forcep head supporting arm, the forcep head can be inserted into the forcep head seat from the opening in the top of the forcep head seat, biopsy forceps do not need to pass through an endoscope forcep channel and are not limited by the forcep channel, the biopsy forceps are suitable for the small-size endoscope forcep channel, and sufficient sampling amount is guaranteed.