39 results about "Endoscopic biopsy" patented technology

The invention belongs to the technical field of pathological diagnosis, and provides a colorectal cancer preoperative lymph node metastasis prediction method based on deep learning and a pathological HE slice, and the method comprises the steps: firstly obtaining an HE slice WS I image of preoperative intestinal endoscopic biopsy of a colorectal cancer patient; performing feature extraction on the WSI image by using a Transform network based on multi-instance learning; a dyeing normalization technology is introduced, and color standardization processing is carried out on the WSI image; according to the colorectal cancer lymph node metastasis prediction method, deep learning and pathological HE slices are combined, the digital level of colorectal cancer lymph node metastasis prediction is improved, by processing and analyzing the WSI images of the HE slices, the model can accurately extract pathological features and generate prediction results within seconds, and the timeliness of clinical decisions is remarkably improved; meanwhile, the model adopts a dyeing normalization technology, and image features are extracted in different channels; the model can keep stable performance in various clinical environments and data sources, and accurate issuing of treatment decisions is promoted.

The present disclosure relates generally to the field of medical instruments. More particularly, the present disclosure pertains to medical instruments for use with an endoscope, such as a biopsy cap and a biopsy cap housing with improved stability and stress distribution, for example, to securely attach to an endoscope biopsy port.

The utility model discloses a pair of multi-angle adjustable endoscopic biopsy forceps, and relates to the technical field of medical instruments, in particular to a pair of multi-angle adjustable endoscopic biopsy forceps which comprises a handle assembly, an inner sliding groove is formed in the middle of the handle assembly, and a rack buckle is arranged above the handle assembly. One side of the rack buckle is in sliding connection with a pliers movable traction block, the other side of the rack buckle is in sliding connection with a pliers rotating traction block, and a transition connecting sleeve is fixedly installed at the end of the handle assembly. According to the multi-angle adjustable endoscopic biopsy forceps, the front head bend, the rotating cylinder and the forceps mounting shaft are arranged in a matched mode, so that the multi-angle adjustable endoscopic biopsy forceps have the effects that the head end can independently rotate, tissue biopsy can be better carried out, and the efficiency is improved; therefore, the multi-angle adjustable endoscopic biopsy forceps have the effect of conveniently controlling the bending of the tail end of the biopsy forceps.

The utility model relates to the technical field of medical instruments, and discloses an endoscopic biopsy valve sealing assembly, which is characterized in that a sleeve ring is arranged at a connecting part of a biopsy valve cover body, an insertion hole assembly is fixed on the sleeve ring through a rope body, and a rod part of a cotton swab head is inserted into an insertion hole of the insertion hole assembly, so that the detachable connection of the cotton swab head and the sealing assembly is realized. The cotton swab head can be quickly disassembled and assembled in the insertion hole assembly; the cotton swab head can be kept on the biopsy valve and cannot fall off or be lost randomly in the biopsy sampling process of opening the cotton swab head to cancel plugging, so that the biopsy valve can be plugged in time after biopsy sampling is completed, the operation is convenient, the problem that the exposure time of the biopsy valve is too long due to the fact that the cotton swab head needs to be cut again can be avoided, and the biopsy sampling efficiency is improved. Therefore, the infection risk of the patient is reduced.

The present invention provides a disposable specimen collector, which relates to the technical field of medical devices. It includes a handheld part, a connecting part and a sampling part. The connecting part is connected between the handheld part and the sampling part. The sampling part is provided with a sampling arm, and the sampling arm is connected with a driving member. The driving member is used to drive the sampling arm to open and close, and a sampling wire basket for collecting specimens is arranged on the sampling arm. The disposable specimen collector provided by the present invention can enter the digestive tract through the endoscopic biopsy hole under the endoscope, enter once and complete the collection and picking of multiple specimens, which is very convenient.

Devices, systems, and methods for a cap adapted to biopsy ports for an endoscope. Multiple internal features of the rotationally symmetrical bore allow for a tight, operative fit when the cap is placed on any of multiple different biopsy ports, even though the ports have significant differences in both height and shape. Alternating lips and grooves within the contour of the internal bore correspond to different bodies and flanges of the biopsy ports.

The endoscopic biopsy device comprises a fixed clamp body, a movable clamp body, a deep barrel, a core rod, a movable block, a clamping plate, a rotating plate, a matching plate and an abutting piece, the rotating plate is provided with a sampling plate through a connecting piece, and the abutting piece is rotationally connected with the clamping plate through a movable piece; through cooperation of the endoscopic system, the deep barrel is close to a sampling position, the clamping plate and the sampling plate extend out of the deep barrel and are unfolded through pushing of the core rod, and then the clamping plate and the sampling plate rotate in the original positions and are in clamping contact with the sampling part, so that the sampling plate completes sampling work; the sampling plate further rotates relative to the clamping plate to be in full contact with the sampling part, and finally moves towards the lateral direction to be further in contact with the sampling part in the process of sliding and scraping along the sampling part along with the drawing of the core rod, so that the sampling sufficiency is ensured, and the mode is convenient to operate and full in sampling; the harm to the respiratory system of a patient is small.

The invention relates to the technical field of medical biopsy instruments, in particular to an endoscopic biopsy device for respiration and critical diseases, which comprises a catheter, a cylindrical sealing piston head is slidably mounted in the catheter, an up-down through vent hole is formed in the sealing piston head, and one end, positioned in vitro, of the catheter is connected with negative pressure; a branch pipe with the tail end sealed is further arranged at the end extending out of the body, a stay wire hole is formed in the center of the sealing piston head, and a stay wire is slidably installed in the stay wire hole. One end of the pull wire extends out of the branch pipe and is provided with a pull ring; one end, far away from the pull ring, of the pull wire is provided with an umbrella-shaped cutting head and a limiting ring; the bottom of the cutting head is provided with a circle of annular cutting edge, the annular cutting edge is located above the sealing piston head, the limiting ring is located below the cutting head, and the distance between the annular cutting edge and the cutting head is larger than the height of the sealing piston head. According to the scheme of combining negative pressure adsorption and mechanical cutting, the tissue sample size larger than that of traditional biopsy forceps can be obtained, and the requirements of pathological examination are effectively met.

1. The name of this design product: Endoscopic biopsy needle (2). 2. Purpose of this design product: used as an endoscope biopsy needle, which is a medical device. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The invention relates to the technical field of medical instruments, and discloses endoscopic biopsy forceps convenient for sampling, which comprise a supporting sleeve and a drawing wire, one end of the supporting sleeve is connected with a flexible tail tube through a connecting hose, the drawing wire penetrates through the supporting sleeve and the connecting hose and extends into the flexible tail tube, and the flexible tail tube is connected with the supporting sleeve. A first pull ring is fixed to one end of the drawing wire, the other end of the drawing wire is rotationally connected with an incomplete gear, a gripper arm is fixed to one side of the incomplete gear, an adjusting mechanism is fixed to the front side of the handle, and the adjusting mechanism penetrates through the side wall of the supporting sleeve and is connected with the outer wall of the flexible tail pipe. According to the endoscopic biopsy forceps convenient to sample, the winding drums can be used for winding the pull ropes, the number of the winding drums is four, the tail ends of the four pull ropes are located on the periphery of the flexible tail pipe, when the rotary knob is held by hand to rotate the rotary sleeve and the rotary shaft, the corresponding winding drums rotate, the corresponding pull ropes pull the flexible tail pipe, the direction of the flexible tail pipe is convenient to adjust, and flexible and accurate sampling is facilitated.

The present invention addresses IBD from the standpoint of mucosal stem cells cloned from defined regions of the gastrointestinal tract. In the case of pediatric Crohn's disease, for example, isolation of those stem cells according to the methods of the present invention reveals a pattern of inflammatory gene expression in stem cells from the terminal ileum and colon that is epigenetically maintained despite months of continuous cultivation in the absence of immune or stromal cells, or of intestinal microbes. Superimposed on this distributed inflammatory phenotype is a differentiation defect that profoundly and specifically alters the mucosal barrier properties of the terminal ileum. The co-existence of diseased and normal stem cells within the same endoscopic biopsies of Crohn's disease patients implicates an epigenetically enforced heterogeneity among mucosal stem cells in the dynamics of this condition.

The invention discloses a protein marker for differential diagnosis of intestinal extracorporeal natural killer / T cell lymphoma and application of the protein marker. The protein marker is composed of COL6A3 and MFAP2 protein. Or the protein is composed of ADAMTS4, COL6A3 and MFAP2 protein. The invention also provides application of a reagent for detecting the protein in preparation of a kit for diagnosing intestinal natural killer cell / T cell lymphoma or evaluating the occurrence risk of the intestinal natural killer cell / T cell lymphoma. According to the invention, the technical bottleneck of difficulty in pathological diagnosis caused by superficial endoscopic biopsy sample of the intestinal ENKTL is effectively solved, and ENKTL can be accurately identified from ulcerative colitis, diffuse large B-cell lymphoma and colon cancer. The method is simple and convenient to operate, the selected antibody is strong in signal and clear in background in IHC detection, a quantitative result with good repeatability and high specificity can be obtained by combining an H-score scoring system, and objectivity and accuracy of pathological diagnosis are remarkably improved.

To provide a biopsy cap and a biopsy cap housing that are capable of realizing a variety of advantageous medical outcomes.SOLUTION: A housing attachment for a biopsy port of an endoscope comprises a first center-split half and a second center-split half. The first center-split half comprises a first portion, a second portion, and one or more locking parts configured to engage the biopsy port. The second center-split half comprises a first portion, a second portion, and one or more locking parts configured to engage the biopsy port.SELECTED DRAWING: Figure 2

The invention discloses an endoscopic living body sampling device for respiration and critical diseases, and relates to the technical field of endoscopic living body sampling. The endoscopic living body sampling device for breathing and critical diseases comprises a spring hose, a handle, a steel wire rope and a movable column arranged in the spring hose, the movable column can be driven to move through the handle and the steel wire rope, the end, away from the handle, of the spring hose is fixedly connected to an installation head, and a guide rod is fixedly connected into the installation head; the side wall of the guide rod is rotationally connected with two clamps, rotation of the clamps is driven by a driving mechanism, and an adsorption mechanism is arranged in the mounting head. According to the endoscopic living body sampling device for respiration and critical diseases, during sampling, a sampling part can be pulled after being adsorbed, so that the sampling part is close to the clamp for clamping and sampling, the sampling position is more accurate, sampling is more convenient and faster, the clamping part can be prevented from loosening or even being separated, and the endoscopic living body sampling device is more stable and reliable; and the sampling efficiency and quality are ensured.

The invention belongs to the technical field of medical equipment, and discloses a novel endoscope microorganism collection tube which comprises a biopsy port connector, a connecting hose is fixedly installed on one side of the biopsy port connector, and a first male Luer connector is fixedly installed on the side, away from the biopsy port connector, of the connecting hose; the first female Luer taper is connected with the first male Luer taper in a matched manner; the invention provides a novel endoscope microorganism collection tube, which comprises a biopsy port connector, a biopsy port extraction tube, a second female Luer connector and a second female Luer connector, the biopsy port connector is inserted into an endoscope biopsy port, the biopsy port connector is inserted into the endoscope biopsy port, the biopsy port connector is inserted into the biopsy port, the biopsy port connector is inserted into the biopsy port, the biopsy port is inserted into the biopsy port, and the biopsy port is inserted into the biopsy port. When the endoscope biopsy opening is a small connector, the first male Luer taper and the first female Luer taper are disconnected, then the first female Luer taper is placed on the endoscope biopsy opening and is gently rotated and locked, and the connector is high in universality and can be suitable for endoscope tubes of various models.

A method of detecting connectivity of a biopsy channel of an endoscope during an endoscope reprocessing procedure may involve connecting a fluid supply line to the biopsy channel and connecting a fluid detection sensor to a suction connector on the endoscope. After connection, fluid may be introduced into the fluid supply line connected to the biopsy channel of the endoscope. The reprocessing machine may determine whether the fluid supply line is properly connected to the biopsy channel of the endoscope based on detection of the fluid by the fluid detection sensor.

The present invention discloses a method for using a mechanical arm-type endoscopic biopsy device, including an end grip plate, the front side wall of the end grip plate is fixedly connected to a sliding guide assembly; the sliding guide assembly includes a sliding guide rod, a cavity is opened in the sliding guide rod; a spring guide component is slidably connected in the cavity, which includes a spring located in the cavity, a guide rod is sleeved on the spring, the rear end of the guide rod is fixedly connected to a spring rear seat, and the front end of the guide rod is slidably connected to a spring front seat; the top of the spring front seat is fixedly connected to a toggle rod, the front side wall of the spring front seat is fixedly connected to a flexible detection rod, the flexible detection rod is connected to a biopsy cone, and a sampling groove is opened in the biopsy cone. At the same time, the present invention discloses a method for using a biopsy device, including pushing a finger-shaped toggle plate, pushing the flexible detection rod to extend into the patient's body, puncturing the biopsy cone, and accommodating tissue fluid and tissue cells in the sampling groove. The above-mentioned device component design can quickly and effectively achieve diseased tissue sampling, effectively improving clinical detection efficiency.

The utility model provides a double-cover endoscopic biopsy cap, which belongs to the medical technical field, the double-cover endoscopic biopsy cap comprises an endoscopic biopsy mechanism and a bottom cover fastening mechanism, the endoscopic biopsy mechanism comprises a conical sleeve for taking out an endoscopic sample, the barrel body of the conical sleeve is conical and is hollow, the upper end and the lower end of the conical sleeve are arranged in a penetrating manner, and the bottom cover fastening mechanism is arranged on the conical sleeve. The device is installed on the outer wall of the pipe diameter of the endoscope, backflow or splashing of body fluid of a patient can be reduced in the endoscope diagnosis and treatment process, hospital infection can be reduced, the transversely-installed biopsy opening blocking pad is beneficial for a diagnosis and treatment doctor to keep complete inflation of the gastrointestinal tract and expose a good endoscope operation view field in the endoscope diagnosis and treatment process, and the accuracy and efficiency of endoscope diagnosis and treatment are improved.

A steerable arm configured for the biopsy channel of an endoscope comprising a continuum structure of a resilient material in the form of a hollow tubular member. The tubular member comprising a tubul

The invention relates to the technical field of medical instruments, and discloses an endoscopic surgery gasket which comprises a conveying system and a gasket system, the gasket system is connected with one end of the conveying system, and the conveying system comprises a pusher, a handle, a conveying pipe and a connecting ring; the gasket system comprises a gasket, a fixator long bent arm, a fixator short arm, a gasket limiting pipe and a gasket limiting ring. By means of the conveying and mounting structure, the gasket system is conveyed into the body through an endoscopic biopsy duct and cushioned between a suture and an organ in the body, the cutting effect of the suture on the organ in the body is reduced, ulcer caused by suture cutting is prevented, the short-arm comb and the long-bent-arm comb are meshed in a tooth shape, the surgical suture is prevented from being disengaged, and the surgical efficiency is improved. And the pad is coated with the slow-release hemostatic coating, the slow-release antibiotic coating and the like, so that hemostatic and anti-infection effects on wounds and fistulization openings are achieved.

The utility model relates to the field of endoscopic biopsy duct flushing, in particular to an auxiliary bracket for endoscopic biopsy duct flushing, which can solve the problems that an auxiliary bracket provided in the background technology is easy to turn over and damage, the height of the bracket needs to be adjusted by two hands, the operation is troublesome, and a culture bottle is easy to slip and break. Comprising a vertical rod, the upper end and the lower end of the vertical rod are respectively and vertically bent backwards to form a bent part, the rear ends of the bent parts are respectively connected with fixing plates, the fixing plates are round, and fixing holes are formed in the edges of the fixing plates in the circumferential direction; a plurality of annular grooves are vertically formed in the outer surface of the vertical rod at intervals, and the vertical rod is sequentially provided with a top fixing part, a middle fixing part and a culture bottle fixing part from top to bottom, wherein the height of the top fixing part can be adjusted with one hand; and an auxiliary fixing piece is fixedly arranged on the bottom surface of the bending part on the upper side. The device is easy to operate, convenient to use and suitable for various endoscopes.

The invention relates to the field of biomedicine, and discloses a method, a system and a kit for constructing a model for predicting the submucosal deep infiltration possibility of colorectal tumor based on molecular characteristics of a biopsy sample under an endoscope, electronic equipment applying the construction method and a computer readable medium storing computer program codes. The construction method comprises the steps of obtaining a plurality of independent variables, carrying out screening and data processing on the independent variables, further screening effective independent variables in a regression model training process, reducing the number of the independent variables, obtaining a relationship among the independent variables through correlation analysis, carrying out replacement and combination by adopting the independent variables with a replacement relationship, and obtaining a regression model. And obtaining a plurality of prediction models. According to the prediction model, a good prediction result can be obtained by using fewer effective independent variables, the prediction efficiency is high, the application range is wide, and the cost is low.

The present disclosure relates generally to the field of medical instruments. In particular, the present disclosure relates to a biopsy cap and endoscope biopsy cap housing with improved stability and stress distribution to securely and removably attach to an endoscope biopsy port. In one example, a biopsy cap housing may include a first center-split half comprising a first half of an upper and lower chamber and first pivot member, and a second center-split half comprising a second half of an upper and lower chamber, and second pivot member, wherein mating surfaces of the first and second center-split halves may be configured to interlock to define the upper and lower chambers.

The application discloses an endoscope biopsy guiding system and a control method. The system comprises an endoscope front-end probe assembly, an image processing host and an operation control terminal. The microscopic image acquisition unit in the endoscope front-end probe assembly is pre-aligned with the physical sampling path of the biopsy tool. The image processing host is configured to acquire a microscopic image, process and generate an evaluation signal representing the pathological value of the target tissue, judge whether the evaluation signal meets the preset trigger condition, and send an enable signal to the operation control terminal to drive the operation limiting unit to release the operation limitation of the sampling execution component when the condition is met. The method comprises corresponding image acquisition, evaluation signal generation, condition judgment and unlocking control steps. By constructing a "verify first and sample later" physical interlocking mechanism, the application can ensure that the sampling operation is only performed in the high pathological value area, effectively avoiding the misoperation caused by blind sampling, and significantly improving the accuracy of biopsy sampling and the positive rate of diagnosis.

The invention provides a pathological physician digital slice actual combat simulation training examination system, and belongs to the technical field of examination systems. Comprising a cloud module, an AI algorithm extraction module, an examination question generation module and an examination question adjustment module. The examination subject adjusting module sets examination subjects, and the examination subjects, including metastatic tumors, small blue circular cell malignant tumors, endoscopic biopsy specimens and lung puncture specimens, are set according to a sub-specialized system according to the requirements of training and teaching major stiffness. The cloud module and the AI algorithm extraction module establish a test question bank according to real clinical cases and establish the test question bank according to the assessment subject, and the test question bank comprises clinical pathology information of the cases. According to the invention, the mastery degree of the pathologists on the diseases is assessed in a real pathologist working scene.

Devices, systems, and methods for a cap adapted to biopsy ports for an endoscope. Multiple internal features of the rotationally symmetrical bore allow for a tight, operative fit when the cap is placed on any of multiple different biopsy ports, even though the ports have significant differences in both height and shape. Alternating lips and grooves within the contour of the internal bore correspond to different bodies and flanges of the biopsy ports.

The utility model relates to the technical field of medical instruments, and discloses an endoscopic surgery gasket which comprises a conveying system and a gasket system, the gasket system is connected with one end of the conveying system, and the conveying system comprises a pusher, a handle, a conveying pipe and a connecting ring; the gasket system comprises a gasket, a fixator long bent arm, a fixator short arm, a gasket limiting pipe and a gasket limiting ring. According to the utility model, the gasket system is conveyed into the body through an endoscopic biopsy duct through the conveying and mounting structure and is cushioned between a suture and an organ in the body, so that the cutting effect of the suture on the organ in the body is reduced, ulcer caused by suture cutting is prevented, and the short-arm comb and the long bent-arm comb are mutually meshed in a tooth-shaped manner, so that the surgical suture is prevented from being disengaged; and the pad is coated with the slow-release hemostatic coating, the slow-release antibiotic coating and the like, so that hemostatic and anti-infection effects on wounds and fistulization openings are achieved.

The utility model discloses a digestive tract endoscopic biopsy pathological sample fixing box, which relates to the technical field of medical supplies, and comprises an embedding box base and an embedding box upper cover, the embedding box upper cover is covered on the embedding box base, a pathological number coding area is arranged above the front side of the embedding box base, and the embedding box upper cover is covered on the embedding box base. A groove is formed in the middle of the upper surface of the embedding box base, at least part of space in the groove forms a specimen fixing area, filter paper is arranged on the bottom wall and the circumferential side wall of the specimen fixing area, and a specimen recognition area is formed in the position, on the rear side of the specimen fixing area, above the embedding box base. And the upper surface of the embedding box base is provided with a two-dimensional code pasting area on the left side of the specimen recognition area. The specimen box has the advantage of preventing the specimen in the box from being lost and polluted by the outside.

The present disclosure relates generally to the field of medical instruments. More particularly, the present disclosure pertains to medical instruments for use with an endoscope, such as a biopsy cap and a biopsy cap housing with improved stability and stress distribution, for example, to securely attach to an endoscope biopsy port.

The present invention discloses a tissue traction device for assisting endoscopic treatment. The tissue traction device is a dumbbell-shaped structure with a connecting line between two O-rings at both ends. The pusher includes a thin tube with a front end connected to a front needle and a rear end connected to a grip rod. Two lumens are axially opened inward from the rear end of the front needle. The front end of the lumen is connected to the peripheral surface of the front needle to form a through hole. The handle and the grip rod are relatively displaced and movably connected. Two metal wires are passed through the lumen of the front needle, and the front end is exposed to the peripheral surface of the front needle. The O-ring holes at both ends of the tissue traction device are respectively stuck on the front end of the metal wire. The rear end of the metal wire passes through the hollow cavity of the hose, passes into the grip rod and is connected to the handle. The present invention can deliver the tissue traction device to the endoscopic surgery area through the endoscopic biopsy channel at any time according to the needs during the operation, without withdrawing the endoscope. The titanium clip can be combined to achieve precise traction in the cavity, effectively reducing the difficulty of surgical operation and improving the speed of surgery.