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Natural composition for improving functions of stomach and intestine and preventing osteoporosis and preparation method of natural composition

A technology for osteoporosis and gastrointestinal function, applied in drug combinations, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve the problem of exacerbating gastrointestinal dysfunction in elderly patients, affecting the quality of life of patients, and stimulating the gastrointestinal tract To achieve the effect of improving spleen and stomach function in the body, preventing osteoporosis, and alleviating osteoporosis

Inactive Publication Date: 2019-09-17
EZHOU INST OF IND TECH HUAZHONG UNIV OF SCI & TECH +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, the commonly used drugs for the treatment of osteoporosis include calcium, active vitamin D, estrogen, bisphosphonates, calcitonin and fluoride, etc. Although they have certain curative effects, they have relatively large adverse reactions.
At the same time, many anti-osteoporosis drugs can stimulate the gastrointestinal tract, cause nausea, nausea and vomiting and other adverse symptoms, aggravate the gastrointestinal dysfunction of elderly patients, and seriously affect the quality of life of patients

Method used

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  • Natural composition for improving functions of stomach and intestine and preventing osteoporosis and preparation method of natural composition
  • Natural composition for improving functions of stomach and intestine and preventing osteoporosis and preparation method of natural composition
  • Natural composition for improving functions of stomach and intestine and preventing osteoporosis and preparation method of natural composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] This example provides a natural composition for improving gastrointestinal function and preventing osteoporosis. The raw materials include: Codonopsis Codonopsis extract 10%, Astragalus extract 25%, Atractylodes macrocephala extract 20%, Chinese yam extract Maca extract 15%, Maca extract 20%, Licorice extract 10%.

[0036] The total saponin content in the Codonopsis Codonopsis extract is ≥100mg / g, and the preparation method is:

[0037] Take an appropriate amount of dried Codonopsis pilosula, mix it with ethanol at a mass volume ratio of 1:8, reflux and extract at 65°C for 5 hours, concentrate the ethanol extract under reduced pressure into a paste, dissolve it with an appropriate amount of distilled water, add an equal volume of petroleum ether for extraction, and collect water Mutually. The aqueous phase was extracted with an equal volume of n-butanol, the n-butanol phase was collected, concentrated and dried to obtain the Codonopsis pilosula extract.

[0038] The t...

Embodiment 2

[0050] This example provides a natural composition for improving gastrointestinal function and preventing osteoporosis. The raw materials include: Codonopsis Codonopsis extract 20%, Astragalus extract 30%, Atractylodes macrocephala extract 15%, Chinese yam extract Maca extract 20%, Maca extract 10%, Licorice extract 5%. Its preparation method is basically consistent with Example 1.

Embodiment 3

[0052] This example provides a natural composition for improving gastrointestinal function and preventing osteoporosis. The raw materials include: Codonopsis Codonopsis extract 15%, Astragalus extract 25%, Atractylodes macrocephala extract 15%, Chinese yam extract Maca extract 15%, Maca extract 20%, Licorice extract 10%. Its preparation method is basically consistent with Example 1.

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Abstract

The invention provides a natural composition for improving functions of stomach and intestine and preventing osteoporosis. The natural composition consists of a radix codonopsis extract, a radix astragali extract, a bighead atractylodes rhizome extract, a Chinese yam extract, a maca extract and a licorice root extract, and the effective ingredients of the components are in interaction, so that gastrin secretion and motilin secretion can be increased, the vasoactive intestinal peptide level of blood vessels is reduced, the functions of the stomach and the intestine are improved, the bone density can be increased, the content of bone minerals of bone calcium, bone phosphorus and the like can be increased, and the effect of relieving osteoporosis can be achieved.

Description

technical field [0001] The invention belongs to the technical field of natural compositions, and in particular relates to a natural composition for improving gastrointestinal function and preventing osteoporosis and a preparation method thereof. Background technique [0002] Osteoporosis (OP) is an age-related degenerative disease that can occur at any age, but is more common in postmenopausal women and elderly men. It is characterized by low bone mass and poor bone microstructure. A systemic bone disease characterized by increased bone fragility and susceptibility to fractures. At present, my country has more than 210 million people over the age of 60 (about 15.5% of the total population), and nearly 140 million people over the age of 65 (about 10.1% of the total population). It is the country with the largest absolute number of elderly people in the world. With the aging of the population, osteoporosis has become an important public health problem in my country. Early ep...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61P1/00A61P19/10
CPCA61K36/284A61K36/31A61K36/344A61K36/481A61K36/484A61K36/8945A61K2236/331A61K2236/51A61K2236/53A61P1/00A61P19/10A61K2300/00
Inventor 余龙江刘浩陈晶晶李东张稀雯金文闻
Owner EZHOU INST OF IND TECH HUAZHONG UNIV OF SCI & TECH
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