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Fuke'an film coated tablet and preparation process thereof

A technology of film coating and preparation process, which is applied to sugar-coated pills, medical preparations without active ingredients, and medical preparations containing active ingredients, etc. Economic benefits, improved product quality, good hydrophobicity

Inactive Publication Date: 2020-04-14
GUANGDONG YILI GROUP PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The coating operation of traditional Fukean sugar-coated tablets takes a long time, and quite a lot of water in the syrup penetrates into the tablet core, which affects the quality of the drug. In addition, a large amount of talcum powder is used in the coating of Fukean sugar-coated tablets, which will cause the powder to fly, and the working environment is not good. Good and other shortcomings, these shortcomings can be overcome by film coating
[0003] Traditional Chinese patent medicine tablets are all coated with sugar, which not only has the disadvantages of easy moisture absorption, fading, cracking, etc., but the weight of a tablet coated with sugar will increase by 70%, and the water absorption rate is high.
In addition, the powdered sugar and talcum powder contained in the sugar coating are not beneficial to middle-aged and elderly people and diabetes.
At the same time, there will be a big difference between the results of the film coating experimental production and the actual production. The increase of the quantity makes the equipment need higher pressure, the concentration needs more cycles or more production time to achieve the result of the experimental production, and the increase of these conditions will lead to the increase of the cost of the enterprise and the reduction of production efficiency, thus giving business burden

Method used

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  • Fuke'an film coated tablet and preparation process thereof
  • Fuke'an film coated tablet and preparation process thereof
  • Fuke'an film coated tablet and preparation process thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1~3

[0024] Embodiment 1~3 prepares sample

[0025] Embodiments 1-3 provide tablet core prescriptions as shown in Table 1.

[0026]

[0027]

[0028] The tablet core preparation process comprises the following steps:

[0029] (1) Weigh and wash the twig vine, plantain, pomegranate peel, fotan mother, and jiubing, add water to decoct, add 6 times the amount of drinking water, decoct for 2 hours, filter to collect the supernatant, add the filter residue 4 times the amount of drinking water is decocted for the second time for 2 hours, and the 2 extracted medicinal liquids are respectively filtered through 80-mesh sieves, pumped into the medicinal liquid temporary storage tank and combined to obtain medicinal liquid A, and placed at room temperature;

[0030] (2) Pump the medicinal liquid A in the medicinal liquid tank into a two-effect vacuum concentrator, heat and concentrate, measure the specific gravity with a hydrometer at any time, concentrate to a clear ointment with a re...

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PUM

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Abstract

Belonging to the technical field of drug coating, the invention particularly relates to a Fuke'an film coated tablet and a preparation process thereof. The Fuke'an film coated tablet is composed of atablet core and a film coating layer, the tablet core comprises the following preparation raw materials: Jasminum elongatum, polygonum chinense, ovateleaf holly bark, plantain herb, pomegranate rind,corn starch, powdered sugar and magnesium stearate; and the film coating layer comprises the following preparation raw materials: mannitol, acetyl triethyl citrate, titanium dioxide, vital gluten, polysorbate-80 and propylene glycol. The Fuke'an film coated tablet has the characteristics of high yield, good stability and low water absorption rate, and is suitable for industrial mass production.

Description

technical field [0001] The invention belongs to the technical field of drug coating, and in particular relates to a film-coated tablet of Fukean and a preparation process thereof. Background technique [0002] Fukean Tablets can clear heat and dampness, astringe and relieve pain, and are used for acute gastroenteritis, abdominal pain, diarrhea, and vomiting caused by indigestion. The coating operation of traditional Fukean sugar-coated tablets takes a long time, and quite a lot of water in the syrup penetrates into the tablet core, which affects the quality of the drug. In addition, a large amount of talcum powder is used in the coating of Fukean sugar-coated tablets, which will cause the powder to fly, and the working environment is not good. Such shortcomings, these shortcomings can be overcome by film coating. [0003] Traditional Chinese patent medicine tablets are all coated with sugar, which not only has the disadvantages of easy moisture absorption, fading, cracking,...

Claims

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Application Information

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IPC IPC(8): A61K9/28A61K47/42A61K47/36A61K36/704A61P1/00A61P1/14A61P1/12A61P1/08A61P29/00
CPCA61K9/2059A61K9/2813A61K9/282A61K9/2826A61K9/2866A61K9/2873A61K9/2893A61K36/185A61K36/63A61K36/68A61K36/704A61K2236/331A61K2236/39A61K2236/53A61P1/00A61P1/08A61P1/12A61P1/14A61P29/00A61K2300/00
Inventor 张浩罗运樟李霞黄灿林于海翠
Owner GUANGDONG YILI GROUP PHARMA
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