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Method for preparing natural ferulic acid by taking nigre containing oryzanol as raw material

A technology of oryzanol and ferulic acid, which is applied in the field of plant extraction and separation, can solve the problems of low efficiency, complicated treatment, and pollution of natural ferulic acid, and achieve the effects of easy temperature control, complete decolorization, and less loss

Active Publication Date: 2020-04-28
HUNAN HUACHENG BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0027] In order to overcome the defects of low extraction and preparation of natural ferulic acid in the prior art, low purity, pollution, complicated treatment, etc., the present invention provides a method for preparing natural ferulic acid using soapstock containing oryzanol as a raw material, which can be produced on an industrial scale White natural ferulic acid with a purity of more than 99%

Method used

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  • Method for preparing natural ferulic acid by taking nigre containing oryzanol as raw material

Examples

Experimental program
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Effect test

Embodiment 1

[0068] 1. Alkali-alcohol hot-melt filtration. 3m ahead 3 Add 1200L of edible ethanol with a concentration of 89% in the extraction tank, put 400kg of oryzanol-containing soapstock raw materials into the extraction tank under constant stirring, continue to add 1200L of edible ethanol with a concentration of 89%, keep stirring continuously and heat, and heat up to 52°C. The pH of the system was adjusted to 9.0 with a 6% dilute sodium hydroxide aqueous solution to dissolve the raw material, and the material was passed through a disc centrifuge while it was hot, and the filtrate was collected to obtain 2650 L of dissolved filtrate.

[0069] 2. Acid precipitation and separation. Adjust the pH of the dissolved filtrate to 6.5 with dilute sulfuric acid with a concentration of 5wt%, stir well, and let stand for 6 hours to make the oryzanol precipitate completely, and collect the centrifugal precipitate by a three-legged sedimentation centrifuge to obtain 261 kg of the centrifugal pre...

Embodiment 2

[0080] 1. Alkali-alcohol hot-melt filtration. 3m ahead 3 Add 1000L of edible ethanol with a concentration of 92% in the extraction tank, put 300kg of oryzanol-containing soapstock raw material into the extraction tank under constant stirring, continue to add 1000L of edible ethanol with a concentration of 92%, keep stirring and heating continuously, and heat up to 55°C. The pH of the system was adjusted to 10.0 with a 5% dilute sodium hydroxide aqueous solution to dissolve the raw material, and the material was passed through a three-legged sedimentation centrifuge while it was hot, and the filtrate was collected to obtain 2160 L of dissolved filtrate.

[0081] 2. Acid precipitation and separation. Adjust the pH of the dissolved filtrate to 7.0 with dilute hydrochloric acid with a concentration of 8 wt%, stir well, and let stand for 5 hours to make the oryzanol precipitate completely, and collect the centrifugal precipitate by a three-legged sedimentation centrifuge to obtain...

Embodiment 3

[0092] Others are the same as in Example 1, the difference is that the pH of the system is adjusted to 9.0 with dilute lye in step (1); the pH of the dissolved filtrate is adjusted to 7.0 with dilute acid in step (2); the alkali alcohol is adjusted with dilute sulfuric acid in step (6) The pH of the hydrolysis filtrate was 4.0. After testing, the finished product has a natural ferulic acid content of 98.73%, is pure white by visual inspection, and has a product yield of 82.31%.

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Abstract

The invention relates to a method for preparing natural ferulic acid by taking nigre containing oryzanol as a raw material. The method comprises the following steps: hot-dissolving and filtering alkali alcohol, carrying out acid precipitation separation, decolorizing an organic solvent at normal temperature, carrying out hot reflux hydrolysis on the alkali alcohol, carrying out cold precipitationseparation, acidifying, carrying out cold standing desalination, refining with an ultrafiltration membrane, decolorizing aluminum oxide, recovering the solvent, carrying out solid-liquid separation, drying and the like. According to the method, the content of oryzanol in the raw materials is increased to 50-70wt%, then the oryzanol is subjected to thermal dissolution, reflux and hydrolysis by using an alkali alcohol solvent, and high-purity pure white natural ferulic acid is obtained through the synergistic effect of oryzanol purification and decoloration before hydrolysis and ferulic acid alcohol solution refining and decoloration after hydrolysis. The process disclosed by the invention has the remarkable advantages of high yield, high purity and complete decolorization; compared with high-temperature concentrated alkali hydrolysis, the reaction is mild, the alkali concentration is low, the use amount is small, and conversion is complete; the production process is simple and low in cost; the product meets the requirements of natural vanillin on the naturalness of raw materials internationally, and obvious economic and social benefits are created.

Description

technical field [0001] The invention belongs to the technical field of plant extraction and separation, and relates to a method for preparing natural ferulic acid by using soapstock containing oryzanol as a raw material. Background technique [0002] Oryzanol exists in rice bran oil and is a mixture of ferulic acid esters mainly composed of triterpene (en) alcohols. It mainly acts on the autonomic nervous system and endocrine center of the diencephalon, can adjust autonomic nervous function, reduce endocrine balance disorders, and improve symptoms of mental and nervous disorders. It also has various physiological functions such as lowering blood lipids, reducing liver lipids, preventing lipid oxidation, and anti-oxidation. In addition, it also has the effect of resisting arrhythmia, which can reduce the excitability of myocardial muscle by regulating the function of autonomic nerves. The lipid-lowering effect of oryzanol can also improve the blood supply of the myocardium ...

Claims

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Application Information

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IPC IPC(8): C07C27/02C07C51/09C07C51/42C07C51/43C07C51/47C07C59/64
CPCC07C51/09C07C51/42C07C51/43C07C51/47C07C59/64
Inventor 黄华学刘庚贵刘永胜
Owner HUNAN HUACHENG BIOTECH
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