A kind of chiral precious metal nanoparticles and its preparation method and application

Abstract

The invention provides a chiral noble metal nanoparticle and a preparation method thereof. The chiral noble metal nanoparticle is a noble metal nanorod whose long axis surface is coated with a noble metal shell arranged helically in a single direction; After the surface of the rod is modified with chiral thiol molecules, it is possible to generate optically active chiral noble metal nanoparticles "bottom-up". The above-mentioned structure and its synthesis method belong to a new breakthrough in the field of nanostructure regulation. The present invention provides The preparation method of chiral noble metal nanoparticles can prepare chiral noble metal nanoparticles with high efficiency, and the yield and cost can be controlled. The obtained chiral noble metal nanoparticles have an unusually stable and clear microstructure, and the circular dichroism signal It is about 600 millidegrees ahead of other materials with similar structures, and has great application prospects in the fields of chiral catalysis, chiral separation, detection of chiral compounds, and chiral optical devices.

Description

technical field [0001] The invention relates to the field of nanocomposite materials, in particular to a chiral noble metal nanoparticle and its preparation method and application. Background technique [0002] All biomolecules in nature have chirality, which is almost the basic feature of living matter, and may even be a necessary condition for the existence of life. It is the discovery of the double helix chiral structure of DNA that unlocks the replication and transmission of life genetic information. Therefore, understanding the chirality of molecules and the selectivity of chiral enantiomers is crucial to understanding the biochemical reactions of life. [0003] In recent years, the synthesis and biological application of chiral inorganic materials with light control ability, such as polarization control, negative refractive index or chiral sensing and detection, are booming. Noble metal nanomaterials can produce Surface plasmon resonance forms a "hot-spot" on the surf...

AI Technical Summary

Problems solved by technology

[0004] At present, there are two main methods for preparing noble metal nanomaterials with chiral structure. The first one is through microfabrication (photoetching, plasma etching or wet etching, etc.) and vapor deposition. The "bottom" processing method constructs a chiral nanostructure. This method requires high precision and stability of production equipment and processing materials, low production efficiency, and relatively low output. The obtained products are easily oxidized and invalidated in the atmosphere.

The second is to assemble multiple non-chiral noble metal nanoparticles into a chiral spatial structure with the help of chiral biomacromolecules (such as DNA, polypeptides, amino acids, etc.). Although this method has been widely used this year, However, there are also problems such as difficult to accurately control the product structure, low yield, unstable product structure, and easy racemization during storage, which affects further applications.

For example, CN103940746A discloses a method of using gold nanorods and mercapto-containing chiral small molecules to incubate under heating to obtain a "side by side" chiral structure. The circular dichroic spectrum is formed by twisting between two gold nanorods signal, and use it to detect copper ions; the material obtained by it is as described in its use, which is susceptible to interference by heteroions in the solution, and its optical performance is not stable. The maximum ellipticity is only 20 millidegrees, which limits its application in other fields. application

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