Method for preparing glycine by utilizing common ion effect

A technology of the same ion effect and glycine, which is applied in the field of clean production technology of glycine, can solve the problems of large energy consumption, cannot be recycled, and low catalytic ability of urotropine, so as to improve the yield and product quality, and reduce by-products. the resulting effect of

Active Publication Date: 2020-05-26
北京长邦科技有限公司
View PDF6 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] 1. The catalytic ability of urotropine is low, and the concentration requirement in the synthetic reaction aqueous solution is high. The production of one ton of glycine needs to consume about 150 kilograms of catalyst, and it is a one-time use and cannot be recycled;
[0005] 2. Urotropine is easy to decompose. Under high temperature or acidic conditions, urotropine will decompose into formaldehyde and ammonia.
[0007] 3. Wastewater containing urotropine, because it contains high concentration of formaldehyde, cannot be biochemically treated, and can only be treated by catalytic oxidation, which greatly increases the difficulty and cost of wastewater treatmen...

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0056] In 2000 liters of glycine synthetic enamel reaction kettle equipped with stirring, heating and circulating water cooling, add 1600 liters of alcohol-water mixed solvent with 70% methanol content, 3 kilograms of catalyst 4-dimethylaminopyridine, 305 kilograms of ammonium chloroacetate, and heat up When the temperature reaches 50°C, the ammonia flow reaction starts, and the temperature is controlled between 55°C and 65°C. When the pH value of the solution reaches 7.0, the ammonia flow is stopped, and the reaction is kept for 30 minutes. Glycine was separated by centrifugation at 55°C, washed with methanol and dried to obtain 175.8 kg of glycine with a glycine content of 98.8% and a chloride ion content of 0.35.

[0057] The centrifuged liquid (mixed solvent for circulating reaction) was sent to the crystallization kettle, and 305 kg of solid ammonium chloroacetate was added, and the temperature was slowly lowered to 10°C. After centrifugation and drying, 65.8 kg of ammoniu...

Embodiment 2

[0059] Take the centrifugate in Example 1, send it to the glycine synthesis kettle, raise the temperature to 50°C, start the ammonia reaction, control the temperature between 55°C-65°C, stop the ammonia flow when the pH value of the solution reaches 7.2 , keep warm for 30 minutes. Glycine was separated by centrifugation at 55°C, washed with methanol and dried to obtain 194.75 kg of glycine with a glycine content of 98.7% and a chloride ion content of 0.39. The yield of glycine is 95.1%.

[0060] The centrifuged liquid (mixed solvent for circulating reaction) was sent to the crystallization kettle, and 305 kg of solid ammonium chloroacetate was added, and the temperature was slowly lowered to 10°C. After centrifugation and drying, 141.2 kg of ammonium chloride was obtained.

Embodiment 3

[0062] Add 1600 liters of alcohol-water mixed solvent with a methanol content of 70%, 104 kg of urotropine, and 305 kg of ammonium chloroacetate in a 2,000-liter glycine synthesis enamel reaction kettle equipped with stirring, heating, and circulating water cooling, and heat up to 50°C , start the ammonia reaction, the temperature is controlled between 55°C-65°C, when the pH value of the solution reaches 7.0, stop the ammonia flow, and keep warm for 30 minutes. Glycine was separated by centrifugation at 55°C, washed with methanol and dried to obtain 168.8 kg of glycine with a glycine content of 98.9% and a chloride ion content of 0.36.

[0063] The centrifuged liquid (mixed solvent for circulating reaction) was sent to the crystallization kettle, and 305 kg of solid ammonium chloroacetate was added, and the temperature was slowly lowered to 10°C. After centrifugation and drying, 63.1 kg of ammonium chloride was obtained.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to a clean production process for preparing glycine in an alcohol-water mixed solvent by utilizing the common ion effect. A novel catalyst pyridine base compound or a traditionalcatalyst urotropine and paraformaldehyde is adopted as the catalyst. The method comprises the following steps: ammoniating ammonium chloroacetate in an alcohol-water mixed solvent under the conditionof a catalyst by introducing ammonia to synthesize glycine, carrying out centrifugal separation to obtain glycine, adding a solid chlorethamin into the mixed solvent obtained by centrifugation, cooling to 0-20 DEG C, and carrying out centrifugal separation to obtain ammonium chloride, and centrifugally separating ammonium chloride to obtain a circular reaction mixed solvent, and circularly carrying out a glycine synthesis reaction.

Description

technical field [0001] The invention relates to a clean production process of glycine, which uses the same ion effect to prepare glycine in an alcohol-water mixed solvent, and belongs to the technical field of chemical production. Background technique [0002] Glycine is an important raw material for products such as glyphosate and glycine ethyl ester hydrochloride, and it can also be refined into food-grade glycine for use. The traditional domestic aqueous phase chloroacetic acid ammonolysis method for glycine production process is as follows: Add an aqueous solution of about 25% catalyst urotropine into a reaction kettle with cooling water, and at the same time add about 80% of chloroacetic acid aqueous solution dropwise and pass it into Ammonia, the ammonolysis reaction is carried out at a pH value of about 7 and a reaction temperature of about 80°C. The ammonolysis reaction liquid containing glycine and ammonium chloride obtained after the reaction is separated by metha...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): C07C229/08C07C227/08C07C227/42C01C1/16
CPCC07C227/08C07C227/42C01C1/164C07C229/08Y02P20/584
Inventor 刘长飞王云鹤李志伟
Owner 北京长邦科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap