Preparation method of self-healing, excellent elastic recovery and antibacterial hydrogel dressing

A technology of elastic recovery and hydrogel, which is applied in the fields of resisting media-borne diseases, bandages, medical science, etc., can solve the problems of non-elastic recovery and unstable dynamic chemical bonds, etc., and achieve excellent elastic recovery and rapid self-healing ability , the effect of low production cost
CN112940286AActive Publication Date: 2021-06-11UNIV OF SCI & TECH BEIJING
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
UNIV OF SCI & TECH BEIJING
Publication Date
2021-06-11

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Abstract

The invention relates to a preparation method of a self-healing, excellent elastic recovery and antibacterial hydrogel dressing, the hydrogel mainly comprises quaternized / N-methylacryloylated chitosan and four-arm benzaldehyde end-capped polyethylene glycol, and blue light irradiation is combined for further crosslinking to prepare the multifunctional hydrogel. The prepared hydrogel has self-healing performance (dynamic covalent bonds), excellent elastic recovery (carbon-carbon double bond crosslinking) and antibacterial performance (quaternary ammonium salt modification), is used for repairing and regenerating skin tissue defects, and has outstanding application prospects in the direction of infected wound healing dressings. According to the present invention, the material has characteristics of rapid self-healing ability, excellent elastic recovery, good mechanical strength, and excellent antibacterial ability. The hydrogel is simple in preparation and operation process and low in production cost, and can be used as an effective novel wound infection dressing in treatment of chronic infection wounds at joints.
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Description

technical field

[0001] The invention belongs to the field of tissue engineering and regenerative medicine, and in particular relates to a self-healing, excellent elastic recovery and antibacterial hydrogel dressing and a preparation method, especially for repairing and regenerating skin tissue defects. Background technique

[0002] Chronic wounds can develop from a variety of conditions—including diabetic neuropathy (diabetic foot ulcers), decubitus ulcers (pressure ulcers), and vascular disease (venous leg ulcers). Because chronic wounds are difficult to heal spontaneously and easy to relapse, chronic wounds are extremely susceptible to pathogenic bacteria infection, eventually resulting in non-traumatic amputation or even death, bringing great pain and challenges to patients and even the entire economy and society. Due to the large population base in my country and the increasing prevalence of diabetes, the treatment of chronic refractory wounds has become an important cli...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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