Method for detecting permanganate radicals by coumarin-based probe

A permanganate and coumarin-based technology is used in the field of environmental and non-standard explosive detection, which can solve the problems of time delay of oxidation reaction, low molar absorption coefficient, poor anti-interference and other problems, and achieves simple production, obvious signal, and cost. low cost effect

Active Publication Date: 2021-06-11
XINJIANG TECHN INST OF PHYSICS & CHEM CHINESE ACAD OF SCI
View PDF9 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most fluorescent probes still have disadvantages such as poor detection limit, low qua

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for detecting permanganate radicals by coumarin-based probe
  • Method for detecting permanganate radicals by coumarin-based probe
  • Method for detecting permanganate radicals by coumarin-based probe

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0030] Example 1

[0031] Synthesis of probe molecule 2-oxo-2 hydrogen-benzopyran-7-acrylate:

[0032] A, 7-hydroxybenzopyran-2-ketone (5 mmol, 0.81 g) was dissolved in 50 ml of tetrahydrofuran, added to 200 ml of three round bottom flasks, and the organic base pyridine (5 mmol, 0.402 mL) was added and stirred. Nitrogen protection, ice bath to 0 ° C, slowly dropped acryloyl chloride (5 mmol, 0.398 ml) reaction for 2 h, warmed to room temperature reaction for 1 h, stopped the reaction;

[0033] B. After the reaction is completed, washed with deionized water to neutral, then extract water, sodium chloride, dry sodium chloride, and dry filtration, and dry filtration;

[0034] C. The obtained crude product was eluted with a forward silica gel column. The eluent was ethyl acetate / petroleum ether, and the eluent proportion was gradually increased from 0: 7 to 2: 7, and the end of the purification was separated. Solid, that is, to detect the probe molecule 2-oxo-2 hydrogen-benzopyran-7...

Example Embodiment

[0035] Example 2

[0036] Synthesis of probe molecule 2-oxo-2 hydrogen-benzopyran-7-acrylate:

[0037] A, 7-hydroxybenzopyran-2-ketone (5 mmol, 0.81 g) was dissolved in 50 ml of trichloromethane, added to 200 ml of three round bottom flasks, and then organic base triethylamine (25.5 mmol, 3.55ml) ) And stir. Tong nitrogen gas protection, ice bath to 0 ° C, slowly dropped acryloyl chloride (25 mmol, 1.99 mL) reaction for 2 h, warmed to a room temperature reaction for 24 h, stopping the reaction;

[0038] B. After the reaction is completed, washed with deionized water to neutral, then extract water, sodium chloride, dry sodium chloride, and dry filtration, and dry filtration;

[0039] C. The obtained crude product was eluted with a forward silica gel column. The eluent was ethyl acetate / petroleum ether, and the eluent proportion was gradually increased from 0: 7 to 2: 7, and the end of the purification was separated. Solid, that is, a probe molecule 2-oxo-2 hydrogen-benzopyran-7-ac...

Example Embodiment

[0040] Example 3

[0041] Synthesis of probe molecule 2-oxo-2 hydrogen-benzopyran-7-methacrylate:

[0042] A, 7-hydroxybenzopyran-2-ketone (5 mmol, 0.81 g) was dissolved in 50 ml of tetrahydrofuran, added to 200 ml of three round bottom flasks, and the organic base pyridine (5 mmol, 0.402 mL) was added and stirred. Nitrogen protection, ice bath to 0 ° C, slowly added additional methyl acryloyl chloride (5 mmol, 0.484 mL) reaction for 2 h, warming to room temperature reaction for 1 h, stopping the reaction;

[0043] B. After the reaction is completed, washed with deionized water to neutral, then extract water, sodium chloride, dry sodium chloride, and dry filtration, and dry filtration;

[0044] C. The obtained crude product was eluted with a forward silica gel column. The eluent was ethyl acetate / petroleum ether, and the eluent proportion was gradually increased from 0: 7 to 2: 7, and the end of the purification was separated. Solid, that is, to detect probe molecules 2-oxo-2 hy...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention provides a method for detecting permanganate radicals by a coumarin-based probe. The coumarin-based probe is 2-oxo-2hydrogen-benzopyran-7-R acid ester, the coumarin-based probe is obtained by condensation of 7-hydroxybenzopyran-2-ketone and acyl chloride, and the response group of the probe to the permanganate radicals is double bonds. The single probe has no fluorescence in a mixed solution of an organic solvent and water, and shows obvious fluorescence lightening response when being used for detecting the permanganate radicals, the response time is less than 3 seconds, and real-time detection of the permanganate radicals can be realized; and the detection sensitivity is high, and the detection limit is as low as 0.95 nmol/L. The method has high selectivity on the permanganate radicals, and the content of the permanganate radicals in a water sample and a non-standard explosive raw material in the environment can be accurately measured by utilizing a standard curve. The method has excellent selectivity and sensitivity, can be used for rapidly detecting the permanganate radicals on site, and has a wide application prospect.

Description

technical field [0001] The invention belongs to the field of detection of environment and non-standard explosives, and provides a method for detecting permanganate with a coumarin-based probe. The probe has low detection limit, strong anti-interference and short reaction time, and can realize the purpose of low-cost and real-time fluorescence detection of permanganate. Background technique [0002] Due to the strong oxidation of permanganate, it is widely used as an oxidizing agent in chemical production, as a preservative, disinfectant, deodorant and antidote in medicine, and as a water treatment agent in water purification and wastewater treatment. It is also used as a bleaching agent for special fabrics, waxes, greases and resins, as an adsorbent for gas masks, as a coloring agent for wood and copper, etc. Studies have shown that high concentrations of KMnO 4 Release into water bodies can cause water pollution, and ingestion of permanganate can cause coagulative necrosi...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): G01N21/64C09K11/07
CPCG01N21/643C09K11/07C09K2211/1088Y02A20/20
Inventor 窦新存万知欣蔡珍珍
Owner XINJIANG TECHN INST OF PHYSICS & CHEM CHINESE ACAD OF SCI
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap