Wet adhesive super-lubricating hydrogel coating and preparation method thereof

Abstract

The invention provides a wet adhesion super-lubricating hydrogel coating and a preparation method thereof. The preparation method comprises the following steps: adding a hydrogel monomer and sodium alginate powder into deionized water, then sequentially adding a cross-linking agent N, N 'methylene bisacrylamide, a cross-linking accelerant tetramethylethylenediamine, a hydrophilic photoinitiator ammonium persulfate and an ionic cross-linking agent calcium sulfate dihydrate, then adding an adhesive, and uniformly mixing to obtain a pre-gel solution; and immersing a substrate in the pre-gel solution, taking out the substrate, placing the substrate at room temperature for illumination, and completing a polymerization reaction through photo-initiation to obtain the wet adhesion super-lubrication hydrogel coating. The obtained hydrogel has a double-network water structure, can effectively dissipate applied stress, is good in mechanical property, and effectively solves the problems of fracture and deformation caused by bending of a coating; meanwhile, good hydrophilicity and good adhesion are achieved. The hydrogel coating is convenient to use and rapid in film forming, and is expected to be applied to medical catheters, Foley catheters, cardiac pacemaker leads and large-scale soft robots.

Description

Technical field: [0001] The invention belongs to the field of medical devices, and in particular relates to a superlubricating hydrogel coating adhered in a wet state and a preparation method thereof. Background technique: [0002] Water lubrication exists widely in many anatomical parts of organisms, including respiratory tract, articular cartilage, internal organs and ocular surface. Good lubrication and low-friction movement play a vital role in maintaining the physiological functions of the human body. Therefore, low boundary friction to tissues is beneficial for medical device applications, but these medical devices usually do not have the ability to lubricate biological interfaces. According to the current study, the hydration layer formed on the underlying substrate is called aqueous lubrication. The confined water in the hydration layer is an important lubricant between sliding surfaces, and when subjected to shear force, the hydration layer can respond in a fluid-...

AI Technical Summary

Problems solved by technology

For example, the Chinese patent with the publication number CN201911214849.8 discloses a hydrophilic lubricating coating, which has better mechanical robustness, but the adhesion is insufficient, which easily causes the coating to fall off

Another example is the Chinese patent whose publication number is CN202110691314.0, which discloses a hydrogel freeze-dried powder coating, which solves the problem of hydrogel dehydration and shedding due to long-term storage, but has the problem of uneven coating, and Hydrogel coatings fabricated by forming or dip coating typically yield relatively thick hydrogel layers (over 50 µm) whose shape is determined by the mold used or the shape of the dip coating surface

These issues greatly hinder the ability of coatings to adapt to devices with complex surface geometries and fine features

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