Vitality-preserving effervescent tablet as well as preparation method and application thereof

A technology of effervescent tablets and compound Baoyuan decoction, which is applied in the field of food and medicine, can solve the problems of easy loss of volatile components, large oral dosage, cumbersome decoction, etc., and achieve improved stability, solubility, and bioavailability High degree, the effect of enhancing the body's immunity

Pending Publication Date: 2022-04-22
UNIVERSITY OF MACAU
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Baoyuan Decoction is currently in the form of decoction, which is cumbersome to decoct, prone to mildew and inconvenient to carry, and easy to lose volatile components
Moreover, the traditional decoction has a large oral volume, bitter taste, poor mouthfeel, and inconvenient to carry, which limits its daily use and industrial preparation

Method used

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  • Vitality-preserving effervescent tablet as well as preparation method and application thereof
  • Vitality-preserving effervescent tablet as well as preparation method and application thereof
  • Vitality-preserving effervescent tablet as well as preparation method and application thereof

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preparation example Construction

[0029] In the second aspect, the embodiment of the present invention provides a preparation method of the above-mentioned medicinal and edible dual-purpose Baoyuan effervescent tablet with the function of enhancing body immunity, which includes: after drying the extract of Compound Baoyuan Decoction, disintegrate with the effervescent tablet in proportion Agents and other auxiliary materials are mixed and tabletted to obtain Baoyuan effervescent tablets.

[0030] In an optional embodiment, the preparation of the Baoyuan effervescent tablet includes the following steps: preparing the extract by means of water extraction and alcohol precipitation, then mixing the extract with a surfactant and then drying to obtain a dry extract powder;

[0031] The obtained dry extract powder is equally divided into two parts, one part is uniformly mixed with an acid agent, a binder and a sweetener, and granulated to obtain the first component, and the other part is mixed with an alkali agent, a ...

Embodiment 1

[0042] Preparation of a medicine-food dual-purpose Baoyuan effervescent tablet capable of enhancing body immunity

[0043] Raw materials according to the following mass ratios: 4 parts of ginseng, 8 parts of astragalus, 2 parts of licorice, 1 part of cinnamon, and 1 part of ginger. Acid agent (2 parts of citric acid, 1 part of malic acid, 2 parts of tartaric acid), 5 parts of alkaline agent (1 part of sodium carbonate, 2 parts of sodium bicarbonate, 2 parts of calcium carbonate), surfactant (dodecyl 1 part of sodium sulfate, 1 part of Tween 80, 1 part of Span 60) 3 parts, binder (1 part of sodium carboxymethyl starch, 1 part of microcrystalline cellulose, 1 part of sodium carboxymethyl cellulose) 3 parts , 5 parts of sweetener (2 parts of xylitol, 1 part of cyclamate, 2 parts of maltitol), 5 parts of lubricant (1 part of magnesium stearate, 2 parts of talc, 2 parts of sodium lauryl sulfate) .

[0044] The preparation method comprises the following steps:

[0045] Take the abo...

Embodiment 2

[0047] Preparation of a medicine-food dual-purpose Baoyuan effervescent tablet capable of enhancing body immunity

[0048] Raw materials according to the following mass ratios: 10 parts of ginseng, 16 parts of astragalus, 5 parts of licorice, 3 parts of cinnamon, and 1 part of ginger. 10 parts of acid agent (4 parts of citric acid, 3 parts of citric acid, 3 parts of tartaric acid), 10 parts of alkali agent (3 parts of sodium carbonate, 3 parts of sodium bicarbonate, 4 parts of calcium carbonate), binder (carboxymethyl Starch sodium 2 parts, hydroxypropyl cellulose 1 part, carboxymethyl cellulose sodium 2 parts) 5 parts, sweetener (xylitol 2 parts, sucrose 2 parts, maltitol 3 parts) 7 parts, lubricant ( 4 parts of magnesium stearate, 3 parts of silicon dioxide, 2 parts of calcium lauryl sulfate) 9 parts.

[0049] The preparation method comprises the following steps:

[0050] Take the above four medicinal materials according to the weight ratio, add 9 times the quality of wate...

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Abstract

The invention discloses a vitality-preserving effervescent tablet as well as a preparation method and application thereof, and belongs to the technical field of foods and medicines. The effervescent tablet comprises a main drug, an effervescent disintegrant and other auxiliary materials. The main medicines comprise five traditional Chinese medicines which are homologous in medicine and food, namely ginseng, astragalus membranaceus, liquorice, cinnamon and ginger. The effervescent disintegrant comprises an acid agent and an alkaline agent. And the other auxiliary materials comprise a surfactant, an adhesive, a sweetening agent, a lubricant and the like. The effervescent tablet prepared by the invention overcomes the defects of the original dosage form of the vigor-preserving decoction, and has the advantages of good stability and dissolvability and high bioavailability. The health-care tea has the characteristics of convenience in taking, quick response, better taste, convenience in carrying, transportation and storage and the like. In addition, the traditional Chinese medicine composition has a relatively good protection effect on a cyclophosphamide-induced mouse hypoimmunity model. The traditional Chinese medicine disclosed by the invention belongs to medicinal and edible medicinal materials, is green, healthy and safe, can be applied to the field of foods and medicines, and can be used as a medicinal and edible dual-purpose product to effectively enhance the body immunity of people with low immunity.

Description

technical field [0001] The invention relates to the technical field of food and medicine, in particular to a Yuanbao Effervescent Tablet and its preparation method and application. Background technique [0002] Baoyuan Decoction has been included in the "Catalogue of Ancient Classical Prescriptions (First Batch)". Classical prescriptions refer to the prescriptions recorded in ancient Chinese classics that are still widely used, have definite curative effects, and have obvious characteristics and advantages. At present, product research and development based on classic famous prescriptions is encouraged. Based on Baoyuan Decoction in "Catalogue of Ancient Classical Famous Prescriptions (First Batch)", Baoyuan Decoction comes from "Concise Medicine" (Ming Sun Zhihong), "treating weak vitality, mental fatigue, slow muscles, less food intake, blue face White, sleeping peacefully, ... and miscellaneous syndromes, all belong to weakness and should be taken. "It is composed of ...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61K9/46A61P37/04A23L33/105A23P10/28
CPCA61K36/258A61K36/481A61K36/484A61K36/54A61K36/9068A61K9/2054A61K9/2009A61K9/0007A61P37/04A23L33/105A23P10/28A23V2002/00A61K2300/00A23V2200/324A23V2250/2124A23V2250/21
Inventor 王一涛陈伟杰王胜鹏钟章锋余华
Owner UNIVERSITY OF MACAU
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