Environment responding aquogel copolymer and its prepn

Abstract

The present invention relates to one kind of environment responding aquogel copolymer and its preparation process. The aquogel consists of: N-isopropyl acrylamide 10-90 wt% and methacrylate dextran derivative 10-90 wt%. The preparation process of the environment responding aquogel copolymer includes chemical modification of dextran with GMA to synthesize methacrylate dextran derivative, MA-Dex, with reaction activity; and subsequent copolymerization of MA-Dex and NIPA to obtain the said environment responding aquogel copolymer P(NIPA-co-MA-Dex). The aquogel copolymer has high temperature sensitivity and quick responding speed as well as high strength and excellent biocompatibility. The preparation process is simple, needs no special apparatus and is easy to realize in industry.

Description

technical field

[0001] The invention relates to an intelligent hydrogel and a preparation method thereof, specifically an environment-responsive N-isopropylacrylamide (N-isopropylacrylamide, NIPA) and a methacrylate dextran derivative (MA-Dex ) copolymerized hydrogel and its preparation method, which belong to the field of functional polymer materials, and the international patent classification number is proposed to be Int.C1 7 C08F20 / 54. Background technique

[0002] Smart hydrogels are a type of hydrogels whose properties will change significantly in response to slight physical or chemical stimuli from the external environment. It is a cross-linked hydrophilic polymer network that is insoluble in water but swellable in water. Typical external environmental stimuli that have been studied include temperature, pH, electric field, ionic strength, solvents, reactants, light, and chemicals. Due to the advantages of high water content and good biocompatibility, smart hydroge...