3 results about "Dextran Derivatives" patented technology

An adhesive composition includes a beta-1,3-glucan derivative having an acyl group introduced in a beta-1,3-glucan, and a petroleum-based resin. An adhesive tape (1) is provided with an adhesive layer (3) formed of the adhesive composition.

The application discloses a temozolomide dexchlorpheniramine derivative and application thereof in preparation of an antitumor drug, and is based on new cognition of a TMZ drug resistance mechanism, designs and synthesizes two temozolomide derivatives. The target compounds retain the alkylating activity of TMZ, and metabolites do not produce 5-amino-imidazole-4 amide (AICA), but produce dexchlorpheniramine derivatives of AICA. Thus, the TMZ chemotherapy sensitivity is enhanced, and the TMZ drug resistance of glioma is delayed or reversed. The application first reconstructs the TMZ molecule from the metabolic product level, breaks through the action mode of the inherent drug resistance, and provides a brand-new drug design idea for overcoming the TMZ drug resistance. A new generation of TMZ derivative drugs can be developed, a single drug or a combined treatment scheme with higher efficacy and lower drug resistance is realized, and more breakthrough treatment options are provided for GBM patients.

Disclosed herein is a method of treating a surface. Such a method can comprise at least: (a) providing a liquid composition comprising at least a solvent, antimicrobial agent, and alpha-glucan derivative, and (b) contacting the liquid composition with a surface, thereby providing antimicrobial activity to the surface. Further disclosed are compositions comprising various alpha-glucan derivatives, and applications of using these derivatives.