Method for preparing drop pills of ageratum vital qi

A technology of Huoxiangzhengqi dripping pills and patchouli oil, which is applied in the field of medicine, can solve the problems of low degree of pure naturalness, low degree of naturalness, unfavorable traditional Chinese medicine dripping pill preparations, etc. of excipients of dripping pills, so as to reduce the irritating smell of drugs and improve the The effect of oral pH and improving oral odor

Active Publication Date: 2006-12-06
TIANJIN TASLY MORDEN TCM RESOURCES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] With the global expansion of the market and the requirement of human beings to return to nature, the use of drugs with low toxicity and side effects, especially pure natural drugs, has become the first choice of people. The dropping pill preparation is a new type of Chinese medicine preparation with high efficiency and quick effect. The shortcomings and deficiencies of traditional Chinese medicine preparations in the past, but the current drop pill preparations generally face the following problems: 1. The drop pill auxiliary materials are not purely natural: at present, most of the drop pill base auxiliary materials are chemically synthesized, and the natural degree is low. New alternatives The search for matrix excipients, especially the search for alternative matrix excipients with a high degree of naturalness and the determination of their preparation process, is also very difficult, because the preparation conditions required for common and possible substitutes for natural matrix excipients are very harsh. And its dripping pill dripping conditions are the key to affect the preparation of dripping pills
If the melting temperature of the excipient is too high, the viscosity will be low and the plasticity will be poor. If the melting temperature of the excipient is too low, although the plasticity is strong, the dropping pills have disadvantages such as easy sticking and deformation. The accessories are very hard work
2. Problems encountered in the export of dripping pills: With the development of the economy, the market is becoming more and more internationalized, and China is also trying to adapt to this trend. Currently, Chinese medicine dripping pills, which are used as health food, have been successfully exported to many countries, but There are also many problems at present, because different countries have different approvals for the excipients selected for the preparation of Chinese medicine dripping pills, especially in Europe with developed industries, which have stricter regulations on food excipients and pharmaceutical excipients, and the drops exported as health food The chemically synthesized auxiliary materials (such as polyethylene glycol) selected for pill preparations are not listed in the food additive catalogs of some countries, which is very unfavorable for Chinese medicine dripping pill preparations to enter the international market, and has become a stumbling block for Chinese medicine t...

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] Embodiment 1: the preparation of active ingredient of medicine of the present invention

[0067] (a) Take Atractylodes 160g, Chenpi 16g, Magnolia officinalis (Ginger) 160g, Angelica dahurica 240g, Poria cocos 240g, Dabupi 240g, Raw pinellia 160g, Dried ginger 13.5g, Licorice extract 20g, Huoxiang oil 1.6ml, perilla leaf oil 0.8ml for later use:

[0068] (b), Atractylodes atractylodes, tangerine peel, Angelica dahurica, Magnolia officinalis add 70% ethanol and reflux extract twice, each time 2 hours, combine extracts, filter, recover ethanol, set aside; One time for 2 hours, the second time for 1 hour, combine the decoction, filter, and concentrate the filtrate to an appropriate amount under reduced pressure, add licorice extract, mix well and set aside; soak the raw pinellia in cold water, change the water every 8 hours, soak until After the heart is penetrated, add another 13.5g of dried ginger, add water and decoct twice, the first time is 3 hours, the second time is...

Embodiment 2

[0070] Get 833g of xylitol and 167g of dextrin and mix evenly, add 50g of the active ingredient of the present invention prepared according to the method of Example 1, heat and melt the mixture at 64°C, stir evenly, the stirring time is 10-30 minutes, keep warm, and heat at 64°C Dropping at high temperature, the diameter of the dropper is 1.2-2.5mm, drop into the methyl silicone oil at 0°C, and make 1050g pellets, drain the formed pellets and wipe off the cooling liquid, and pack them after drying, that is, have to.

Embodiment 3

[0072] (a), take 80g of Atractylodes atractylodis, 80g of tangerine peel, 240g of Magnolia officinalis, 120g of Angelica dahurica, 360g of Poria cocos, 120g of Dabupi, 80g of raw pinellia, 10g of licorice extract, 0.8ml of patchouli oil, and 0.4ml of perilla leaf oil for later use;

[0073] (b), Atractylodes atractylodes, tangerine peel, Angelica dahurica, Magnolia officinalis add 40% ethanol and reflux extract twice, each time 3 hours, combine extracts, filter, recover ethanol, set aside; 3 hours for the first time, 2 hours for the second time, 1 hour for the third time, combine the decoction, filter, concentrate the filtrate to an appropriate amount under reduced pressure, add licorice extract, mix well and set aside; soak the raw pinellia in cold water, every 10 hours Change the water once, soak until the heart is clear, add another 13.5g of dried ginger, add water to decoct twice, the first time is 3.5 hours, the second time is 1.5 hours, combine the decoction, filter, and ...

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Abstract

A dripping pill of agastache for treating cold, vomiting, diarrhea, heat stroke and cholera features high natural level and safety and low toxic by-effect. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a preparation method of Huoxiangzhengqi dripping pills. Background technique [0002] The prescription of Huoxiang Zhengqi comes from Huoxiang Zhengqi Powder contained in "Taiping Huimin Hejiju Prescription Volume 2". Tangerine peel, Platycodon grandiflora, and licorice, this prescription has the effect of relieving the exterior, harmonizing the middle, and aromatizing the turbidity. It is mainly used for exogenous wind and cold, internal stagnation of dampness or feeling of heat dampness, external symptoms such as cold and heat headache, and internal chest and abdomen fullness. Anorexia, vomiting, nausea, abdominal pain and diarrhea, pale mouth with greasy coating, moist and slow pulse and other symptoms of damp resistance. This prescription is often used for those with the above syndromes such as gastrointestinal cold, acute gastroenteritis or indigestion...

Claims

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Application Information

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IPC IPC(8): A61K36/889A61K9/20A61P1/04A61P1/08A61P1/12A61P1/14
CPCY02A50/30
Inventor 李永强郑永锋
Owner TIANJIN TASLY MORDEN TCM RESOURCES
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