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97 results about "Cell determination" patented technology

Cell determination is influenced by the action of the extracellular environment and the contents of the cell's genome. When a cell is said to be determined it means that the cell is irreversibly committed to a specific cell fate.

Aggregated white blood cell segmentation counting system and method

The invention discloses an aggregated white blood cell segmentation counting system. The system comprises an image acquisition module for dyeing white blood cells in a blood sample, dissolving red blood cells in the blood sample by using red blood cell lysate and acquiring a white blood cell image, an image preprocessing module used for performing image background removal on the white blood cellimage and obtaining an optimal segmentation threshold by using a maximum inter-class variance method and roughly segmenting a white blood cell region, an aggregated cell determination module used forobtaining a coarse segmentation image according to the rough segmentation of the white blood cell region, setting a discriminant function of a cell area and obtaining a multi-cell aggregation region,and an aggregated cell segmentation counting module used for extracting a cytoskeleton in each aggregation region and a gray curve at the cytoskeleton by using a morphological refinement method. According to the invention, by analyzing the gray scale characteristics of various white blood cell areas under a low power microscope, an adaptive threshold function is constructed, while a white blood cell count is obtained, the number of oxyphil cells is obtained, the cells in the aggregation region are quickly and accurately divided and counted, the method is quick and simple and is easy to implement.
Owner:JIANGSU KONSUNG BIOMEDICAL TECH

Method for detecting antigen expression level by using flow cytometry

The invention discloses a method for detecting an antigen expression level by using a flow cytometry. The method comprises the steps of firstly, carrying out immunofluorescent staining on a target cell, then detecting the stained cell by adopting the flow cytometry and carrying out data calculation and analysis, wherein when the parameter of the low cytometry is set, the resolution of a fluorescence channel to be detected is reduced; and obtaining a geometric average fluorescence intensity of an isotype control or a negative cell and a target cell to-be-detected antigen, figuring out respective geometric average fluorescence intensity rates with the geometric average fluorescence intensity rate of the isotype control or negative cell as a critical value, and if the geometric average fluorescence intensity rate of the target cell to-be-detected antigen is higher than that of the isotype control or negative cell by a preset value, the expression of the target cell to-be-detected antigen is achieved. According to the invention, the accuracy and the precision of target cell determination are effectively increased, experimental errors and subjective judgment errors of weak antigen expression are maximally reduced, and the flow cytometry is effectively promoted to be applied to multiple fields.
Owner:JIANGSU PROVINCE HOSPITAL

Parameter updating method and device for TD-LTE (Time Division Long Term Evolution) system

The invention provides a parameter updating method and device for a TD-LTE (Time Division Long Term Evolution) system. The parameter updating method includes the steps of: obtaining cell determination identifiers and the scene distinguishing parameter of each cell; determining the cell scene type of each cell according to the scene distinguishing parameter of each cell; generating first correspondence between the cell determination identifiers and the cell scene types according to the cell determination identifiers and the cell scene types; generating third correspondence among the cell determination identifiers, parameters to be updated and parameter values according to the first correspondence and preset second correspondence among the parameters to be updated, the parameter values and the cell scene types; generating a parameter configuration file of eNBs (Evolved Node Base station) to be updated according to the third correspondence; and sending the parameter configuration file to the eNBs to be updated to allow each eNB to be updated to resolve the third correspondence from the parameter configuration file, and updating the parameter value corresponding to each parameter to be updated according to the respective cell determination identifier and the third correspondence. According to the parameter updating method and device, the maintenance cost of network can be reduced.
Owner:DATANG MOBILE COMM EQUIP CO LTD
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