2 results about "Magnesium aluminosilicate" patented technology

The application belongs to the technical field of pharmaceutical preparations, and particularly relates to a self-emulsifying nanometer preparation of tofacitinib and a preparation method thereof. The tofacitinib free base is mixed with diethylene glycol monoethyl ether, and is dissolved by heating and oscillation; then polyoxyethylene 40 hydrogenated castor oil and glyceryl monocaprylate are added, and are uniformly stirred to obtain a drug-containing SEDDS solution; the SEDDS solution is added dropwise into magnesium aluminosilicate to obtain a SEDDS solidified powder. The method significantly improves the solubility and stability of the tofacitinib free base, simplifies the production process, improves the bioavailability and safety of the drug, provides various preparation forms, and meets the medication needs of different patients.

The invention relates to the technical field of radiation refrigeration materials, in particular to a method for preparing a calcium magnesium silicate radiation refrigeration coating based on yellow phosphorus slag, which comprises the following steps: S1, mixing the yellow phosphorus slag and magnesium oxide according to the weight ratio of (2: 1)-(10: 1), and ball-milling to obtain precursor powder; s2, sintering the precursor powder at 800-1200 DEG C for 4-12 hours to generate a calcium magnesium silicate primary reaction product; s3, ball-milling and sieving the primary reaction product to obtain the calcium magnesium silicate radiation refrigeration powder material with the particle size of 800-4000 meshes; s4, mixing aluminum dihydrogen phosphate, calcium magnesium silicate powder and water according to the mass ratio of (1: 2: 1)-(1: 3: 2), adding a dispersing agent, a wetting agent, a flatting agent and a defoaming agent, and uniformly stirring to obtain a radiation refrigeration coating; and S5, the surface of a solid substrate is coated with the radiation refrigeration coating to form a wet coating, and the radiation refrigeration coating is obtained after drying. The coating disclosed by the invention is easy to produce and has a good application prospect in the building industry.