6 results about "Photocoagulations" patented technology

The invention belongs to the technical field of experimental animal models, biomedical research and immunology, and discloses a photocoagulation thymus ischemia animal model, a method and application of the photocoagulation thymus ischemia animal model in rapid simulation of thymus degeneration and immune senescence, and the model shows at least one or more characteristics 1-7 days after induction: thymus atrophy, thymus weight or thymus index is significantly reduced; the cortical-medullary structure of thymus is disordered or disappears; the expression distribution of the Keratin 5 / Keratin 8 is abnormal; thymic cell apoptosis is increased, and lipid deposition is enhanced; the proportion of CD4 + CD8 + double positive T cells is reduced, and the proportion of DN2 / DN3 stage T cells is increased; the initial T cell output is reduced; and the immune function is reduced. The pathological mechanism is clear; the modeling period is short, and the immune senescence phenotype can be stably obtained within several days; the injury focus is controllable, and systemic stress or hormone interference is avoided; the model has high repeatability and is suitable for mechanism research and drug screening.

The application discloses a fundus laser region selective treatment system based on real-time determination of a galvanometer coordinate, relates to the field of ophthalmic laser treatment instruments, and aims at the problems that in existing fundus laser treatment, the protection of the forbidden irradiation area depends on manual or software judgment, multi-point scanning is difficult to adapt to the lesion contour, and treatment energy is difficult to be graded and matched, and proposes the following scheme: the system comprises a host computer, an FPGA controller, a galvanometer scanning unit, a 577nm laser emission unit and an eyeball movement tracking unit, the host computer generates a fundus region mapping table and corresponding graded energy parameter groups, the FPGA controller performs table lookup determination according to the current scanning point coordinates fed back by the galvanometer scanning unit, and controls the 577nm laser emission unit to perform laser on-off, pulse modulation and power adjustment, and the eyeball movement tracking unit provides offset data to the FPGA controller to correct the coordinate reference. The application is suitable for laser photocoagulation treatment of fundus diseases.

Apparatus (100, 400, 500) for medical treatment includes a contact lens (150, 302, 308, 602) having a front side (151) and a concave rear side (153), which is shaped to contact a front surface (155) of an eye (142) and comprises multiple protrusions (162, 304, 310) extending from the rear side and configured to contact and depress respective points around a sclera (168) of the eye. A laser (108) generates a beam (113) of optical radiation. A scanner (110) directs the beam through the front side of the contact lens to impinge sequentially on at least some of the protrusions so as to photocoagulate tissue in the eye in proximity to the respective points.

The invention relates to the technical field of medical equipment, in particular to a photocoagulation treatment tip which comprises a laser handle, a laser working tip is arranged on the left side of the laser handle, a laser optical fiber coupling connector is integrated in the laser working tip, and the right end of the laser optical fiber coupling connector is fixedly connected with an FC connector. The outer surface of the FC connector is connected with an FC connector in the left end of the laser handle in a clamped mode, the whole left end of the laser working tip is in a horseshoe shape, the inner wall of the left end of the laser working tip is of a sole-shaped structure, and rhombic anti-skid patterns are etched on the outer surfaces of the upper side and the lower side of the horseshoe-shaped left end of the laser working tip. The laser working tip can be quickly inserted, pulled and replaced, the laser handle can be repeatedly used, a standardized interface is matched, an Iridex semiconductor laser and other mainstream hosts are adapted, equipment does not need to be transformed, the problems that a traditional integrated type interface cannot be repeatedly used and is high in cost are solved, and the problems that a split type interface is poor in compatibility and high in energy loss are solved.

An intraocular cyclophotocoagulation device having a proximal, reusable portion and a distal, disposable portion. The reusable portion includes laser treatment assembly comprising a laser diode and a collimating lens positioned a distance distal to the laser diode and configured to collimate light from the laser diode into a collimated laser beam and direct the collimated laser beam towards a distal end region of the proximal housing portion; and an imaging assembly. The disposable portion includes a laser guide extending through an elongate shaft and an aspheric lens positioned within the distal housing portion to receive the collimated laser beam from the proximal reusable portion and direct the collimated laser beam toward a proximal end of a fiberoptic of the laser guide and an illumination light guide and an illumination source positioned within the distal housing portion. Related devices, systems, and methods are provided.