Polyalcohol integral separation medium and preparation process thereof

Abstract

The invention discloses an integral separating dielectric of polymer and making method, which has regular three-dimensional frame structure constituted by polymer frame and through-out hole, wherein the nanometer grade middle-hole is formed on the surface of the polymer frame and / or in the polymer frame; the through-out hole is between 0. 1um and 10um and the middle hole is between 0nm and 50 nm; the frame size is 0. 2-2um. The invention has regular and sequent dielectric structure to be separated after doing chemical decoration for frame surface, which has huge applying potential in the macromolecular separating and purifying and solid phase extracting domain.

Description

technical field

[0001] The invention relates to a polymer monolithic separation medium and a method for preparing the same. Background technique

[0002] With the continuous advancement of science and technology, especially the rapid development of life science and pharmaceutical industry, a large number of complex biological samples and drugs urgently need to be separated and prepared, and separation science is facing great challenges. However, due to the limitation of column efficiency, it is difficult for the commonly used granular packing media to achieve efficient and rapid separation of separation objects. In addition, the granular packed column requires high packing technology, and a little carelessness may easily cause the column to collapse or stop flow. In order to adapt to the advancement of science and technology, it is urgent to develop a chromatographic packing medium that is both efficient and capable of rapid separation.

[0003] Monolithic separation media...

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