Antibacterial medical suture and production method thereof

A technology of suture and tensile strength, which is applied in the field of antibacterial medical suture and its preparation, which can solve the problems of skin tissue dyeing, difficult coating processing, low adhesion between substrate and coating, etc., to prevent wound infection , Accelerate the healing of infected wounds and reduce the effect of antibiotic application

Active Publication Date: 2013-09-11
珠海拓爱医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Although silver ions have broad-spectrum antibacterial properties, their coating processing is difficult, because the first prerequisite for coating the surface of titanium-nickel memory alloy sutures is to ensure that the shape memory of the sutures is maintained after coating, and the thread body conforms to medical metal sutures. Otherwise, once it loses its memory function or other physical properties change, it will lose the meaning of clinical suture use
Therefore, when using any coating process, it should be considered whether it will affect the change of the physical properties of the substrate. If the electroplating method is used to coat the surface of the titanium-nickel memory alloy suture, there will be pollution such as cyanide and residual substances harmful to the human body.
In addition, the temperature is generally 70-90°C or even higher, and the film layer is too thick, which affects the mechanical structure of the titanium

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0025] The antibacterial medical suture thread of the present invention uses titanium-nickel memory alloy wire as a base material and adopts a DC magnetron sputtering method to deposit a silver ion plating layer on the surface of the base material. The preparation method thereof includes the following steps:

[0026] 1) Substrate preparation:

[0027] Select the prepared titanium-nickel memory alloy wire, the diameter of the alloy wire is 0.10~0.5mm, the phase transition temperature is 33℃, the shape memory is a straight line, and it is wound on a stainless steel reel. The medical alloy wire meets the YY / 0816-2010 medical industry standard Regulations: After repeated bending test and torsion test (deflection angle from zero position 40°, bending times is 20, and torsion times is 10), the metal wire should not be broken, and there should be no visible cracks on the surface; mechanical properties: tensile resistance Strength ≤400Mpa, elongation ≥10%;

[0028] 2) Target preparation:

[...

Example Embodiment

[0102] Example 1

[0103] An antibacterial medical suture thread, using titanium-nickel memory alloy wire as a substrate, and depositing a silver ion plating layer on the surface of the substrate by a DC magnetron sputtering method. The preparation method thereof:

[0104] The titanium-nickel memory alloy wire is selected as the base material, the wire diameter is 0.2±0.01 mm, the phase transition temperature is 33°C, the shape memory is linear, and the mechanical properties meet the requirements of the YY / 0816-2010 pharmaceutical industry standard: repeated bending test and torsion test , The metal wire should not be broken, and there should be no visible cracks on the surface; the tensile strength is 375Mpa, and the elongation rate is 19%.

[0105] After the stains on the surface of the substrate are removed, it is placed in the vacuum chamber of the winding continuous DC magnetron sputtering equipment, using high-purity silver as the sputtering target, using a hollow cylindrical i...

Example Embodiment

[0107] Example 2

[0108] An antibacterial medical suture thread, using titanium-nickel memory alloy wire as the base material, and using medium frequency magnetron sputtering to deposit a silver ion plating layer on the surface of the base material. The preparation method thereof:

[0109] The titanium-nickel memory alloy wire is selected as the substrate, the diameter of the wire body is 0.15mm±0.01, and the performance of the substrate: the phase transition temperature of the substrate is 33℃, and the shape memory is a straight line. The mechanical properties meet the requirements of the YY / 0816-2010 pharmaceutical industry standard: After repeated bending tests and torsion tests, the metal wire should not be broken, and there should be no visible cracks on the surface; tensile strength 385Mpa, elongation 15%.

[0110] After the stains on the surface of the substrate are removed, it is placed in the vacuum chamber of the winding continuous intermediate frequency magnetron sputter...

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Abstract

The invention discloses an antibacterial medical suture and a production method thereof. A titanium-nickel memory alloy thread is adopted as a base material of the antibacterial medical suture. A silver-ion cladding layer with thickness of 0.1-1 micrometer is deposited on the surface of the base material. The production method includes depositing the silver-ion cladding layer on the base material in winding-type continuous coating equipment by a physical vapor deposition method. The antibacterial medical suture has functions of sterilization and bacteriostasis, and silver ions contact with positions of cuts, wounds and needle holes, so that infection prevention and resistance are realized; the antibacterial medical suture further keeps all properties of existing titanium-nickel memory alloy while having an antimicrobial property, is stable in chemical property, and can meet the requirements on stitching of infected wounds and seborrheic cuts; rejection is avoided during long-term in-vivo implantation, mechanical property is not changed, and the purposes of freeness of trauma, hyperplasia and in-vivo foreign matters are achieved.

Description

technical field [0001] The invention relates to an antibacterial medical suture and a preparation method thereof. Background technique [0002] Ordinary silk suture skin often leaves obvious stitches or even scars on both sides of the incision margin, which not only affects the appearance, but sometimes is accompanied by itching, acupuncture-like pain and other discomforts. To this end, people have carried out various explorations on suturing skin materials. [0003] At present, the hospital clinically uses a medical suture thread made of titanium-nickel memory alloy wire, and one or both ends of the suture thread are connected with suture needles of different specifications and shapes made of stainless steel, such as triangular needles, curved round needles, Straight circular needles, spade needles, etc., use the shape memory function of titanium-nickel memory alloy and the superelasticity after phase transition, suture with intradermal suture method, make the wound butt a...

Claims

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Application Information

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IPC IPC(8): A61B17/06C23C14/16C23C14/22
Inventor 韩永俊
Owner 珠海拓爱医疗科技有限公司
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