Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Granular quinocetone premix and preparation method thereof

A quinocetone premix and quinocetone technology are applied in pharmaceutical formulations, medical preparations containing active ingredients, animal feed, etc., and can solve problems such as physical and mental health of operators, environmental pollution around the plant, and uneven dispersion of feed. Guarantee physical and mental health, simple and easy preparation process, consistent color effect

Inactive Publication Date: 2015-09-23
ZHEJIANG ESIGMA BIOTECH CO LTD
View PDF3 Cites 8 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the main preparation method of quinocetone premix at home and abroad is: directly mix the quinocetone bulk drug with suitable auxiliary materials such as calcium carbonate or / and corn starch to prepare powdered quinocetone premix, and the powder premix is ​​stored and used. It is easy to absorb moisture and agglomerate during the process, and it is unevenly dispersed in the feed, and a large amount of dust will be generated during the production process, which will pollute the plant and the surrounding environment, seriously affect its cleanliness, and also have a serious impact on the physical and mental health of the operators.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Granular quinocetone premix and preparation method thereof
  • Granular quinocetone premix and preparation method thereof
  • Granular quinocetone premix and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Embodiment 1 quinocetone content is the granular premix (100kg) of 5%

[0029] 3kg β-cyclodextrin is uniformly dispersed in 40kg mass fraction of 50% ethanol-water solution by stirring to make a suspension for use; 5kg quinocetone (purity 99.6%), 89kg montmorillonite and 3kg cyclamate are added and mixed Mix evenly in the machine. During the mixing process, the above-mentioned β-cyclodextrin-ethanol suspension is atomized and added to the mixture through an atomizing gun to obtain a soft material of quinocetone; the obtained soft material is granulated by an extrusion granulator, and then Use a spherical shot blasting machine to get spherical pellets, put the pellets into a high-efficiency boiling dryer to dry, control the inlet air temperature at 100-120°C, and gradually increase the outlet air temperature, when it reaches 60°C, stop Heating, cooling to 40°C, discharging. The dried premix granules are classified and sieved with 20 mesh and 80 mesh to obtain a granular...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
particle sizeaaaaaaaaaa
particle sizeaaaaaaaaaa
Login to View More

Abstract

The invention discloses a granular quinocetone premix which comprises the following components in parts by weight: 5 to 50 parts of quinocetone, 41 to 89 parts of montmorillonite, 2 to 4 parts of sodium cyclamate and 3 to 5 parts of bonder. A preparation method for the granular quinocetone premix comprises the following steps of: uniformly mixing the components and a wetting agent through a mixing machine, then pelletizing by a squeezing granulator, shot blasting by a spherical shot blasting machine, sieving and drying to obtain the granular quinocetone premix with granularity of 20 to 80 meshes. The quinocetone premix is uniform in granules, mellow and full in appearance, accordant in color and luster, good in fluidity and stable in product quality and can be mixed with feed uniformly as well as has better effects on diarrhea prevention and growth promotion of beasts and birds; the preparation method for the granular quinocetone premix has the advantages of high granulation rate, environment-friendliness, dust free and capability of effectively avoiding cross infections.

Description

technical field [0001] The invention relates to a veterinary drug premix, in particular to a montmorillonite-containing granular quinocetone premix and a preparation method thereof. Background technique [0002] The chemical name of quinocetone is: 3-methyl-2-cinnamoyl-quinoxaline-1,4-dioxide, and the molecular formula is C 18 h 14 N 2 o 3 , Light yellow or yellow-green powder, insoluble in water, slightly soluble in some organic solvents, sensitive to light, prone to photochemical reactions. The structural formula is as follows: [0003] [0004] Quinocetone belongs to quinoline drugs. It is a new antibacterial, antidiarrheal, and growth-promoting drug for livestock and poultry developed by Lanzhou Institute of Animal Husbandry and Veterinary Medicine, Chinese Academy of Agricultural Sciences. Antibacterial for livestock and poultry, cure diarrhea and promote growth; it can also be used for antibacterial and growth promotion in aquaculture, improve survival rate, an...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/16A61K31/498A61K47/02A23K1/16A61P1/12A61P3/00
Inventor 王贤玉王丽陈贵才聂月美张丽佳崔志文
Owner ZHEJIANG ESIGMA BIOTECH CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com