Granular quinocetone premix and preparation method thereof

Abstract

The invention discloses a granular quinocetone premix which comprises the following components in parts by weight: 5 to 50 parts of quinocetone, 41 to 89 parts of montmorillonite, 2 to 4 parts of sodium cyclamate and 3 to 5 parts of bonder. A preparation method for the granular quinocetone premix comprises the following steps of: uniformly mixing the components and a wetting agent through a mixing machine, then pelletizing by a squeezing granulator, shot blasting by a spherical shot blasting machine, sieving and drying to obtain the granular quinocetone premix with granularity of 20 to 80 meshes. The quinocetone premix is uniform in granules, mellow and full in appearance, accordant in color and luster, good in fluidity and stable in product quality and can be mixed with feed uniformly as well as has better effects on diarrhea prevention and growth promotion of beasts and birds; the preparation method for the granular quinocetone premix has the advantages of high granulation rate, environment-friendliness, dust free and capability of effectively avoiding cross infections.

Description

technical field [0001] The invention relates to a veterinary drug premix, in particular to a montmorillonite-containing granular quinocetone premix and a preparation method thereof. Background technique [0002] The chemical name of quinocetone is: 3-methyl-2-cinnamoyl-quinoxaline-1,4-dioxide, and the molecular formula is C 18 h 14 N 2 o 3 , Light yellow or yellow-green powder, insoluble in water, slightly soluble in some organic solvents, sensitive to light, prone to photochemical reactions. The structural formula is as follows: [0003] [0004] Quinocetone belongs to quinoline drugs. It is a new antibacterial, antidiarrheal, and growth-promoting drug for livestock and poultry developed by Lanzhou Institute of Animal Husbandry and Veterinary Medicine, Chinese Academy of Agricultural Sciences. Antibacterial for livestock and poultry, cure diarrhea and promote growth; it can also be used for antibacterial and growth promotion in aquaculture, improve survival rate, an...

AI Technical Summary

Problems solved by technology

At present, the main preparation method of quinocetone premix at home and abroad is: directly mix the quinocetone bulk drug with suitable auxiliary materials such as calcium carbonate or / and corn starch to prepare powdered quinocetone premix, and the powder premix is ​​stored and used. It is easy to absorb moisture and agglomerate during the process, and it is unevenly dispersed in the feed, and a large amount of dust will be generated during the production process, which will pollute the plant and the surrounding environment, seriously affect its cleanliness, and also have a serious impact on the physical and mental health of the operators.

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