Preparation method of betaine

Abstract

The invention discloses a preparation method of betaine. Specifically the method comprises the following steps: uniformly mixing glycine methyl ester, acetonitrile and sodium bicarbonate, dropwise adding methyl methanesulfonate, and stirring to enable the materials to react for 16 to 32h; adding a sodium hydroxide solution into reactant, rising the temperature to 50 DEG C, stirring to enable the materials to react for 20 h, then distilling to remove solvent, obtaining filtrate through filtering, removing foreign ions through adsorption, distilling the filtrate at ordinary pressure, collecting precipitated solid, performing vacuum drying, and then obtaining the betaine. All the raw materials related involved in the synthetic method adopted can be purchased in the market, and the operation of all the steps is simple, and the product cost can be effectively reduced; the condition of each step in the reaction is mild, and the safety is high; toxic and harmful substances are not produced, so the method is green and environmentally friendly; the yield of reaction products is high, and the method is easy for large-scale popularization and application.

Description

technical field [0001] The invention relates to the field of chemical industry, in particular to a preparation method of betaine. Background technique [0002] The chemical name of betaine is betaine, and its molecular formula is: C 5 h 11 NO 2 , Molecular weight: 117.15, white fluid crystal powder, melting point: 293°C (decomposition), chemical structure similar to amino acid. Betaine itself is an intermediate product of metabolism in animals. It has been proved by a large number of experiments that betaine and its salts are non-toxic, harmless and non-polluting, and are recognized as safe substances. Betaine can promote animal fat metabolism, relieve stress, regulate As a feed additive, it plays an important role in animal husbandry. It participates in the metabolism of biological organisms, forms a methyltransferase with cysteine, and provides active methyl groups. Adding it to animal feed can ensure the health of livestock and poultry. Healthy growth, increase the co...

AI Technical Summary

Problems solved by technology

Simultaneously, also can have a small amount of heavy metal substance to be mixed in the product, these impurity all have destroyed the quality of main product betaine greatly, can't satisfy some fields that have special requirement to salt content; The second method is to use choline as raw material ( WO2001040818), under the catalysis of noble metals (such as Pt), obtain betaine with oxygen oxidation, but this method uses noble metals, and the use of oxygen also requires special conditions, so the cost is higher, which is not conducive to large-scale production; The method requires the use of highly toxic chemicals (such as diazomethane, etc.), which has no operational significance in actual production

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