Usage of streptomyces psammoticus and vanillin production method

Abstract

The invention discloses a usage of streptomyces psammoticus and a vanillin production method. The streptomyces psammoticus is Streptomyces psammoticus OMK-4 and used for vanillin production. The streptomyces psammoticus is adopted for production of vanillin according to a fermentation method which includes steps of strain activation, seed culture, fermentation, extraction and the like. By means of the microbiological fermentation method for vanillin production, raw materials including ferulic acid and the like are adopted for generation of a target product through microbial metabolism. The vanillin production method is implemented under the conditions of low temperature and low pressure, thereby having the advantages of high safety, operational simplicity, less pollution and environment friendliness.

Description

technical field [0001] The invention relates to the use of Streptomyces sandra and a production method of vanillin. Background technique [0002] Vanillin, also known as vanillin, molecular weight: 152.14. White to light yellow crystals, melting point 81°C, boiling point 284-285°C, relative density 1.060, flash point 147°C, solubility: 10g / L (25°C), soluble in organic solvents such as ethanol. Found in Peru balsam, clove bud oil, vanilla, coffee, grapes, brandy, has vanilla smell, very sweet taste. [0003] Vanillin is not only an important spice, but also an important chemical raw material and an important pharmaceutical intermediate. In food, because of its vanilla bean aroma, it is widely used as a fixative in various foods. In medicine, vanillin is a raw material for the synthesis of pharmaceutical intermediates, and can be used to produce raw materials for the treatment of high blood pressure, heart disease, and commonly used drugs for skin diseases. [0004] 1. Che...

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Problems solved by technology

[0008] 4) p-Hydroxybenzaldehyde, p-nitrotoluene method, p-cresol method: these three methods have not yet industrialized production due to various reasons (p-Hydroxybenzaldehyde is due to the high price of raw materials; the p-cresol method has harsh reaction conditions and low yield ; The p-nitrotoluene method requires relatively large equipment)

[0009] 5) Safrole method: safrole is mainly derived from camphor oil, the reaction route is long, and there are by-products, which are not easy to separate

However, the separation of enzymes and the directional transformation and modification of enzymes need further research, and this method is still in the research stage.

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