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Traditional Chinese medicine composition for removing moisture and relieving itching and preparation method and application of traditional Chinese medicine composition

The technology of a composition and a traditional Chinese medicine is applied in the field of dehumidification and itching-relieving plant composition and its preparation field, which can solve the problems of many adverse reactions, high recurrence rate, inability to improve the condition of patients, etc. Effects of allergic skin reactions

Inactive Publication Date: 2016-08-03
华芮科技(深圳)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These drugs are effective in dispelling dampness and relieving itching, with clear curative effect and rapid onset, which belong to symptomatic treatment, but there is a high recurrence rate after stopping the drug, and there are many adverse reactions, such as drowsiness, dry mouth, dizziness, etc.
Reliance on medication alone does not improve patient condition compared to high incidence of eczema disease

Method used

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  • Traditional Chinese medicine composition for removing moisture and relieving itching and preparation method and application of traditional Chinese medicine composition
  • Traditional Chinese medicine composition for removing moisture and relieving itching and preparation method and application of traditional Chinese medicine composition
  • Traditional Chinese medicine composition for removing moisture and relieving itching and preparation method and application of traditional Chinese medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] a. Take 500g of ginseng, 500g of Ganoderma lucidum, and 1000g of Ophiopogon japonicus, add 5.0L of distilled water, cook in a boiling water bath for 2 hours, extract the water, then add 5L of water and continue boiling for 2 hours, combine the two water extracts, concentrate under reduced pressure, and evaporate 2 / 3 water, and the concentrated extract was freeze-dried at -80°C to obtain freeze-dried powder.

[0038] b. Take 1000g of Scutellaria baicalensis, 1500g of ginkgo leaves and 500g of licorice, add 10L volume fraction of 95% ethanol aqueous solution at room temperature and extract 3 times at room temperature, each time for 24h, combine the three extracts, filter and concentrate under reduced pressure at 60°C, steam In addition to ethanol, the concentrated extract was freeze-dried at -80°C to obtain freeze-dried powder.

[0039] c. Soak 250 g of white tea in warm water at 80°C for 2 hours, collect the leachate, filter and evaporate 2 / 3 of the water at 60°C under r...

Embodiment 2

[0042] The basic formula of the cream that has antipruritic dehumidification protective effect of the present invention is as follows:

[0043]

[0044] The cream with antipruritic, dehumidifying and protective effects prepared by the present invention has milky yellow paste in appearance, between Ph5.6-6.5, heat-resistant at 48°C for 30 days, cold-resistant at -5-15°C for 30 days, and is normal after returning to room temperature .

Embodiment 3

[0046] Prove the effect of the medicine of the present invention by pharmacodynamic experiment below.

[0047] The antipruritic and antiallergic effects of the present invention are verified from animal experiments.

[0048] 1. Local itching reaction experiment in guinea pigs induced by histamine

[0049] Take 40 white guinea pigs, ♀ Half and half, divided into 4 groups at random, i.e. blank control group (distilled water), cream base group, cream group (containing 2% extract, i.e. the cream with antipruritic, dehumidifying and protective effect of embodiment 2), positive control group (diphenhydramine cream), 10 rats in each group. The day before the experiment, the dorsal hair of the right hind foot of each guinea pig was cut off, and shaved with an electric shaver, with an area of ​​about 1 cm×0.5 cm. After 24 hours, the corresponding test drug was administered transdermally, and the blank group was not administered, 1 time / d, for 5 consecutive days. 60 minutes after t...

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Abstract

The invention discloses a traditional Chinese medicine composition for removing moisture and relieving itching. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 10-20 parts of ginseng, 10-20 parts of ganoderma lucidum, 20-30 parts of radix ophiopogonis, 20-30 parts of scutellaria baicalensis, 15-30 parts of ginkgo leaves, 1-5 parts of propolis, 10-15 parts of liquorice and 5-10 parts of white tea. The traditional Chinese medicine composition disclosed by the invention is capable of preventing and nursing skin diseases, particularly has the advantages of high efficiency, security, good controability and no toxic or side effect in nursing and preventing eczema, dermatitis and tinea, and provides novel options for clinical skin prevention and treatment on skin diseases.

Description

Technical field: [0001] The invention belongs to the field of cosmetics, and in particular relates to a plant composition for dehumidification and antipruritic and its preparation method and application. Background technique: [0002] Eczema is caused by a variety of internal and external factors. It is a common allergic, non-infectious and allergic inflammatory skin disease of the epidermis and superficial dermis. The onset of eczema is mainly on the extremities, and its clinical manifestations are characterized by symmetry, exudation, itching, pleomorphism, and recurrence. The main symptoms of eczema are erythema, papules, blisters, etc. on the skin, which may have severe itching, local exudation, erosion after scratching, infection and suppuration, and often repeated attacks. [0003] The anti-eczema drugs currently clinically used mainly include: (1) antihistamines, such as the 1st, 2nd and 3rd generation antihistamines. (2) Anaphylaxis mediator blockers, such as sodiu...

Claims

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Application Information

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IPC IPC(8): A61K36/8968A61P17/00A61P37/08A61P31/10A61P17/04A61K35/644
CPCA61K35/644A61K36/074A61K36/16A61K36/258A61K36/484A61K36/539A61K36/82A61K36/8968A61K2236/331A61K2236/333A61K2300/00
Inventor 蓝蜀锋文佳颖
Owner 华芮科技(深圳)有限公司
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