Preparation method of Fe3O4@Au nuclear shell function material

Abstract

The invention discloses a preparation method of an Fe3O4@Au nuclear shell function material. The preparation method includes the following steps that S1, Fe3O4 nano-particles are added to methyl alcohol and mixed evenly, so that a solution A is obtained; S2, polymine and the methyl alcohol are subjected to oscillating dissolution, potassium hydroxide and carbon disulfide are added, the mixture is stirred for 10-15 minutes and dropwise added to the solution A obtained in the step S1, vibration is carried out for 5-8 minutes, standing is carried out, precipitation water is used for carrying out cleaning, and then Fe3O4@PEI-DTC nano-particles are obtained and added into water to be evenly mixed, so that a solution B is obtained; and S3, the solution B obtained in the step S2 is dropwise added to a chloroauric acid aqueous solution, vibration is carried out continuously in the dropwise adding process, then standing is carried out, precipitation water is used for carrying out cleaning, water is added to be evenly mixed, then a solution C is obtained, a sodium borohydride aqueous solution is dropwise added to the solution C, vibration is carried out continuously in the dropwise adding process, then standing is carried out, and precipitate is extracted and washed, so that the Fe3O4@Au nuclear shell function material is obtained.

Description

technical field [0001] The invention relates to the technical field of nanomaterials with a magnetic core-shell structure, in particular to a Fe 3 o 4 Preparation methods of @Au core-shell functional materials. Background technique [0002] Nanocomposites with core-shell structure have attracted extensive attention in recent years because of their special structures and properties. Composite magnetic nanoparticles with ferrite as the core and gold as the coating have also become one of the research hotspots in the field of core-shell nanocomposites. [0003] Fe 3 o 4 Magnetic nanomaterials are important magnetic materials with superparamagnetism, low Curie temperature, high resistivity, large dielectric constant and stable physical and chemical properties, but they are prone to agglomeration. In order to improve their chemical stability and biocompatibility, we need further surface modification of iron oxides. Because gold has good chemical stability and biocompatibili...

AI Technical Summary

Problems solved by technology

Shi Yanfeng and others used PEI as a protective agent to prepare monodisperse Fe with a diameter of about 40 nm by microwave synthesis. 3 o 4 Nanoparticles, further synthesized Fe with a core-shell structure by the "layer-by-layer method" and "seed growth method" 3 o 4 @Au nanoparticles, this synthesis method is simple, but gold nanoparticles are prone to agglomeration; in addition, Qin Huan et al. used mPEG-SH as a binder to modify Fe 3 o 4 Nanoparticles, also synthesized by the seed-grown Fe 3 o 4 @Au nanoparticles can be used as a multifunctional probe for tumor cell imaging by NMR and photoacoustic targeting specific cells at the same time. Although this method can synthesize nanoparticles with a core-shell structure, the synthesized particles are not only easy to agglomerate, And obtained Fe 3 o 4 @Au nanoparticles have a wide particle size distribution and are not uniform in size

[0005] In addition, the above methods also have other common problems, such as: Au particles 3 o 4 The surface has poor adhesion and is easy to form from Fe 3 o 4 surface detachment

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