A method for rapid determination of vitamin B1 and vitamin C in multi-dimensional tablets

Abstract

The invention discloses a method for rapid determination of vitamin B1 and vitamin C in a multivitamin tablet. The method comprises the steps of: (1) sample treatment: conducting dissolution, extraction, centrifugation, filtration and other pretreatment steps on a sample to obtain a filtrate; (2) sample analysis: employing an in situ spray ionization device to perform analysis, sucking the filtrate and methanol in a volume ratio of 1:1 and using the mixture to fill a drawn borosilicate glass capillary, inserting a metal microelectrode, placing the glass capillary at the front end of an ion mobility spectrometer sample introduction port, applying spray voltage to ionize the sample, letting the sample enter a drift tube, performing separation, and then conducting detection by a faraday cup detector. The method for rapid determination of vitamin B1 and vitamin C in the multivitamin tablet provided by the invention has the advantages of simple operation, low cost, fast analysis speed, good specificity and accurate quantitation, also because of small volume, mobility and strong maneuverability of the ion mobility spectrometer, the method is expected to achieve field rapid analysis and determination of samples, and has wide application prospects.

Description

technical field [0001] The invention relates to the field of detection methods, in particular to a rapid determination of vitamin B in multidimensional tablets 1 and vitamin C methods. Background technique [0002] Vitamin B 1 Also known as thiamine or antineurin, it is a vitamin necessary to maintain the normal function of the heart, nervous system and digestive system, mainly found in meat and vegetables. In organisms, it is an important biocatalyst - the main component of carboxylated coenzyme. When it is lacking, it will lead to a series of diseases, such as beriberi, multiple neuritis and so on. Vitamin C, also known as L-ascorbic acid, can promote the metabolism of tyrosine and tryptophan and prolong the life of the body. It is an essential component of skin cell interstitium and is widely distributed in various fresh fruits and vegetables. When it is deficient, it is easy to suffer from scurvy and other diseases. [0003] With the acceleration of the pace of today...

AI Technical Summary

Problems solved by technology

Vitamin B 1 Vitamin C and vitamin C belong to a class of trace organic substances that the human body maintains normal physiological functions, but when taken in excess, a series of side effects will occur, such as vitamin B in the body 1 Overdose can cause body trembling, herpes, edema, rapid heartbeat, and allergies; overdose of vitamin C can cause certain adverse reactions, such as diarrhea, skin rashes, and uric acid stones, etc.

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