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A new type of gynecological daughter curcuma oil suppository

A technology of gynecological daughter and curcuma oil, which is applied in the direction of suppository delivery, drug combination, plant/algae/fungus/moss components, etc., can solve the problems of drug content reduction, unacceptable by patients, and influence on curative effect, so as to achieve high recovery rate and effective Wide range of effective effects

Inactive Publication Date: 2020-05-12
上海市静安区芷江西路街道社区卫生服务中心
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The 2012 Chinese Women’s Reproductive Tract Infection Summit was held in Changsha, China. Several participating experts pointed out in interviews that rectal administration of drugs has a significant effect on gynecological inflammation, especially in the treatment of upper and lower reproductive tract diseases such as pelvic inflammatory disease, vaginitis, and adnexitis. , the curative effect is obviously better than other types of drugs; after oral administration of the drug through the digestive tract, it needs to enter the body circulation through liver metabolism, the drug content is greatly reduced, affecting the curative effect, and many drugs can also stimulate the gastrointestinal tract to cause nausea, vomiting, stomach pain , stomach burning sensation, etc., which are difficult for patients to accept
Yet about novel gynecological daughter curcuma oil suppository of the present invention, there is no report yet

Method used

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  • A new type of gynecological daughter curcuma oil suppository
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  • A new type of gynecological daughter curcuma oil suppository

Examples

Experimental program
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Effect test

Embodiment 1

[0018] Embodiment 1 Preparation of gynecological daughter curcuma oil suppository of the present invention (1)

[0019] (1) Take the raw materials according to the following proportions: 16 parts of Qianjinba, 16 parts of Rosa Radix, 16 parts of Gongluomu, 16 parts of Caulis Spatholobus, 9 parts of Duanmianzhen, 9 parts of Andrographis paniculata, 9 parts of Dangshen, 9 parts of Angelica, 15 parts of zedoary oil; (2) According to the above-mentioned ratio of medicinal materials, take Andrographis paniculata, Angelica, and Codonopsis pilosula, and grind them into fine powder to obtain crude drug powder 1; (3) According to the above-mentioned ratio of medicinal materials, take single-faced needle and Gongluomu, add water and decoct twice , add 9 times of water for the first time and decoct for 3 hours, add 6 times of water for the second time and decoct for 2.5 hours, combine the decoction, filter, and concentrate the filtrate to clear paste 1 with a relative density of 1.10-1.20...

Embodiment 2

[0020] Embodiment 2 Preparation of gynecological daughter curcuma oil suppository of the present invention (two)

[0021] (1) Take the raw materials according to the following proportions: 14 parts of Qianjinba, 14 parts of Rosa japonica, 14 parts of Gongluomu, 14 parts of Caulis Spatholobus, 7 parts of Duanmianzhen, 7 parts of Andrographis paniculata, 7 parts of Dangshen, 7 parts of Angelica, 10 parts of zedoary oil; (2) Take andrographis paniculata, Angelica sinensis, and Codonopsis pilosula according to the above-mentioned ratio of medicinal materials and grind them into fine powder to obtain crude drug powder 1; (3) Take single-faced needle and Gongluomu according to the above-mentioned ratio of medicinal materials, add water to decoct twice , add 9 times of water for the first time and decoct for 3 hours, add 6 times of water for the second time and decoct for 2.5 hours, combine the decoction, filter, and concentrate the filtrate to clear paste 1 with a relative density of...

Embodiment 3

[0022] Embodiment 3 Preparation of gynecological daughter curcuma oil suppository of the present invention (three)

[0023] (1) Take the raw materials according to the following proportions: 18 parts of Qianjinba, 18 parts of Rosa Radix, 18 parts of Gongluomu, 18 parts of Spatholobus Spatholobus, 11 parts of Duanmianzhen, 11 parts of Andrographis paniculata, 11 parts of Dangshen, 11 parts of Angelica, 20 parts of zedoary oil; (2) grind andrographis paniculata, angelica, and Codonopsis pilosula into fine powder according to the above-mentioned ratio of medicinal materials, and obtain crude drug powder 1; (3) take single-faced needle and Gongluomu according to the above-mentioned ratio of medicinal materials, add water to decoct twice , add 9 times of water for the first time and decoct for 3 hours, add 6 times of water for the second time and decoct for 2.5 hours, combine the decoction, filter, and concentrate the filtrate to clear paste 1 with a relative density of 1.10-1.20; (...

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Abstract

The invention relates to a novel gynecological Qianjin zedoary turmeric oil suppository. The preparation method comprises the following steps: (1) taking raw materials: radix flemingiae macrophyllae, radix rosae laevigatae, caulis mahoniae, caulis spatholobi, radix zanthoxylum echinocarpum, herba andrographis, radix codonopsis, radix angelicae sinensis and zedoary turmeric oil; (2) preparing extractives; (3) heating and melting polyethylene glycol 6000 and poloxamer 188 in water bath, adding tween-80, the zedoary turmeric oil and extractives, stirring evenly and fully, keeping warm, pouring into a suppository mold coated with liquid paraffin on the surface, and obtaining the Qianjin zedoary turmeric oil suppository after cooling. According to the novel gynecological Qianjin zedoary turmeric oil suppository, drug parts of gynecological Qianjin capsules are integrated with the zedoary turmeric oil to prepare the suppository, plugging the suppository into a vaginal can treat vaginitis and cervicitis; plugging the suppository into a rectum can treat dysmenorrhea, amenorrhea, soreness of waist, annexitis, endometritis, chronic pelvic inflammatory disease and the like, and the suppository can also be used in a menstrual period. Rectal blood circulation is very rich, the drug does not pass through an upper gastrointestinal tract after the suppository is used, gastrointestinal irritation is avoided, the drug can be quickly absorbed to reach a pelvic cavity and plays a therapeutic effect, and obvious toxic and side effects are avoided.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a novel gynecological daughter curcuma oil suppository. Background technique [0002] Fuke Qianjin Tablets or Fuke Qianjin Capsules are mainly used for excessive leucorrhea, lower abdomen, lumbosacral pain, mental fatigue, chronic pelvic inflammatory disease, etc. Among them, lumbosacral pain and chronic pelvic inflammatory disease have a significant effect. Fuke Qianjin Tablets, 6 tablets at a time, 3 times a day, taken with warm water. Because the tablets were too large and too many, and gastrointestinal reactions occurred, the dosage form of capsules was added later, 2 tablets at a time, 3 times a day, with warm water Delivery service, 14 days as a course of treatment. After taking Fuke Qianjin Capsules, some patients still had gastrointestinal reactions. After the emergence of poisonous capsules, many patients were disgusted with capsule dosage forms o...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/02A61K36/9066A61P15/00A61P29/00
CPCA61K9/0014A61K9/0034A61K9/02A61K36/19A61K36/232A61K36/29A61K36/344A61K36/48A61K36/486A61K36/738A61K36/758A61K36/9066A61K47/20A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 程曼文
Owner 上海市静安区芷江西路街道社区卫生服务中心
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