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Selenium-enriched rice plant selenoprotein capsule material and preparation method thereof

A technology of plant selenoprotein and selenium-enriched rice, which is applied in the field of selenium-enriched rice plant selenoprotein capsule materials and its preparation, can solve the problems of delayed dissolution of capsule contents in capsule shells, poor water solubility of gelatin shells, and broken capsules. Avoid viscosity and strength decrease, improve elasticity, good mechanical properties

Inactive Publication Date: 2017-12-12
AGRI RESOURCE & ENVIRONMENT RES INST GUANGXI ACADEMY OF AGRI SCI +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The unique structural characteristics of gelatin molecules make it have some disadvantages and deficiencies in application, such as easy cross-linking with drugs containing aldehydes, reducing sugar-syl compounds and vitamin C, which makes the water solubility of the gelatin shell poor, leading to capsule shell disintegration and Delay in the dissolution of the capsule contents; long-term storage in a low-humidity environment, it is easy to become brittle and cause the capsule to break, etc.

Method used

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  • Selenium-enriched rice plant selenoprotein capsule material and preparation method thereof
  • Selenium-enriched rice plant selenoprotein capsule material and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] 1. Preliminary preparation:

[0031] Preparation of selenium-enriched rice plant selenoprotein: in parts by weight, put 200 parts of selenium-rich rice into 5000 parts of acidic solution and soak for 4 hours, grind into a slurry and filter, add 1000 parts of extract and 3 parts of Surfactant, extract at 25°C for 150min, filter with an ultrafiltration membrane, add 4 times the volume of acetone solution to the resulting liquid for precipitation, take the precipitate at a temperature of 55°C, and dry it with a moisture content of 1 %, under the condition that the color difference value is 12, the vacuum drying treatment is carried out to obtain the selenium-enriched rice plant selenoprotein.

[0032] Preparation of the extract solution: in parts by weight, mix 1000 parts of pure water, 10 parts of sodium chloride and 12 parts of 8% sodium hydroxide solution, and stir evenly to obtain the extract solution.

[0033] The substance prepared above is used in the preparation m...

Embodiment 2

[0037] 1. Preliminary preparation:

[0038] Preparation of selenium-enriched rice plant selenoprotein: by weight parts, put 200 parts of selenium-rich rice into 5000 parts of acidic solution and soak for 4.5 hours, grind into a slurry and filter, add 1000 parts of extract and 4 parts to the filtrate Parts of surfactant, extract at 33°C for 170min, filter with ultrafiltration membrane, add 4 times the volume of acetone solution to the resulting liquid for precipitation, take the precipitate at a temperature of 58°C, and the moisture content after drying 1.3% and a color difference of 13 to carry out vacuum drying treatment to obtain selenium-enriched rice plant selenoprotein.

[0039] Preparation of the extract solution: in parts by weight, 1000 parts of pure water, 13 parts of sodium chloride and 25 parts of 8.5% sodium hydroxide solution were mixed, and the extract was obtained after uniform stirring.

[0040] The substance prepared above is used in the preparation method of...

Embodiment 3

[0044] 1. Preliminary preparation:

[0045] Preparation of selenium-enriched rice plant selenoprotein: in parts by weight, put 200 parts of selenium-rich rice into 5000 parts of acidic solution and soak for 5 hours, grind into slurry and filter, add 1000 parts of extract and 5 parts of Surfactant, extract at 35°C for 190min, filter with an ultrafiltration membrane, add 4 times the volume of acetone solution to the resulting liquid for precipitation, take the precipitate at a temperature of 61°C, and dry it with a moisture content of 1.4 %, under the condition that the color difference value is 13, vacuum drying is carried out to obtain selenium-enriched rice plant selenoprotein.

[0046] Preparation of the extract solution: in parts by weight, 1000 parts of pure water, 18 parts of sodium chloride and 19 parts of 9% sodium hydroxide solution were mixed, and the extract was obtained after uniform stirring.

[0047] The substance prepared above is used in the preparation method ...

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Abstract

The invention discloses a selenium-enriched rice plant selenoprotein capsule material. The selenium-enriched rice plant selenoprotein capsule material comprises the following raw materials in parts by weight: 10 to 20 parts of selenium-enriched rice plant selenoprotein, 15 to 20 parts of sodium alginate, 6 to 11 parts of water-soluble cellulose, 13 to 28 parts of carboxymethyl starch, 5 to 9 parts of collagen, 8 to 14 parts of okra extract, 3 to 5 parts of hyaluronic acid, 1 to 3 parts of glycerinum, 2 parts of vitamin E and 150 to 200 parts of deionized water. The invention also discloses a preparation method of the selenium-enriched rice plant selenoprotein capsule material. The raw materials can be completely dispersed and combined tightly, adsorption of a human body is benefited, and the capsule material has high mechanical property under the condition of low humidity, is favorable for storage and transportation of capsules, and has great market promotion value.

Description

【Technical field】 [0001] The invention relates to the field of capsule materials, in particular to a selenium-enriched rice plant selenoprotein capsule material and a preparation method thereof. 【Background technique】 [0002] Soft capsule is a packaging method of capsules, which is commonly used in medicine or health food. It is made of capsules with gelatin, glycerin or other suitable pharmaceutical auxiliary materials alone or mixed. After ingestion, the content is released quickly, and the utilization rate in the body is high. [0003] At present, soft capsule products on the market mainly use gelatin as the main ingredient. Gelatin is obtained by hydrolysis of animal bones and skins. It is a biological macromolecule with a ternary helical structure and has good biocompatibility and physical and chemical properties. The unique structural characteristics of gelatin molecules make it have some disadvantages and deficiencies in application, such as easy cross-linking with...

Claims

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Application Information

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IPC IPC(8): A61K47/42A61K47/36A61K47/38A61K47/46A61K47/10A61K47/22A61K9/48C07K1/14A23J1/12A23J3/14
CPCA61K9/4825A23J1/12A23J3/14A23V2002/00A61K9/4816C07K1/145A23V2250/1626A23V2250/5482
Inventor 刘永贤潘丽萍梁潘霞兰秀农梦玲黄雁飞鹿士杨陈锦平尹艳镇王道波
Owner AGRI RESOURCE & ENVIRONMENT RES INST GUANGXI ACADEMY OF AGRI SCI
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