Bitter gourd and polypeptide composite buccal tablets capable of reducing blood sugar and preparation method of bitter gourd and polypeptide composite buccal tablets

A bitter gourd polypeptide and blood sugar-lowering technology, applied in the direction of food science, etc., can solve the problems of inability to guarantee the stability and significance of product efficacy, no controllability of component quality and content, long preparation time period, etc., and achieve insulin receptor Strong binding ability, guaranteed stability and significance, and remarkable effect of lowering blood sugar

Inactive Publication Date: 2018-01-16
何静仁 +2
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AI Technical Summary

Problems solved by technology

[0004] Although it has been recognized that bitter melon is a plant raw material with hypoglycemic effect, and it is used in the treatment of diabetes, there are some problems at the same time: First, most of the above-mentioned literature and related Chinese medicine herbal preparations for the treatment of diabetes use various Such formula raw materials are directly pulverized and sieved and then filled and taken, or directly decocted with water or pulverized and then decocted with water. There is no quality controllability and content of key ingredients, and the stability and significance of product efficacy cannot be guaranteed; There are hypoglycemic products that use bitter gourd extracts. Most of the bitter gourd extracts are mainly saponins, which are actually "bitter melon saponins", or the bitter gourd polypeptide protein is obtained by various enzymatic reactions or alkaline extraction and acid precipitation, but its content is not high. High, and the preparation time period is long or the operating temperature of some steps is high, and the natural active bitter melon polypeptide is the key component to effectively regulate blood sugar metabolism

Method used

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  • Bitter gourd and polypeptide composite buccal tablets capable of reducing blood sugar and preparation method of bitter gourd and polypeptide composite buccal tablets
  • Bitter gourd and polypeptide composite buccal tablets capable of reducing blood sugar and preparation method of bitter gourd and polypeptide composite buccal tablets

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preparation example Construction

[0026] Further, the preparation method of this bitter gourd polypeptide extract comprises:

[0027] a. The bitter gourd raw material is extracted with purified water, and centrifuged to remove slag to obtain a centrate.

[0028] Optionally, choose fresh bitter gourd or dried bitter gourd and bitter gourd seeds as bitter gourd raw materials. The cleaning method is: firstly wash the raw bitter gourd raw materials with tap water, and then wash them with electrolytic high-concentration ozone water. The ozone concentration in the cleaning water can reach 10-20 mg / L , The water flow rate is 150-450L / h, which is used to further remove pesticide residues, microbial residues, etc.

[0029] Further, the method for extracting bitter gourd raw materials with purified water includes: pouring the crushed bitter gourd raw materials into an ultrasonic assisted extraction tank, adding 5 to 10 times the mass of purified water at 38 to 52°C, and adjusting the system by using buffer salts pH = 6...

Embodiment 1

[0052] This embodiment provides a hypoglycemic bitter gourd polypeptide compound buccal tablet, which comprises:

[0053] Bitter gourd polypeptide extract 4Kg, planted ginseng extract concentrate 3Kg, Pueraria flavonoids extract 2Kg, Polygonatum polysaccharide extract 2Kg, nutritional yeast 0.7‰. Among them, the content of bitter melon polypeptide in the bitter gourd polypeptide extract is 28%, the content of the bitter gourd polypeptide with a molecular weight of 5.5-7kDa is 22%; the content of ginsenosides in the planted ginseng extract is 15%; 60%; Polygonatum Polysaccharides content in Polygonatum polysaccharides extract is 21%.

[0054] The preparation method of the bitter gourd polypeptide compound buccal tablet comprises:

[0055] a. Combine bitter gourd polypeptide extract, planting ginseng extract concentrate, kudzu root flavonoid extract, Polygonatum polysaccharide extract and nutritional yeast with 3% microcrystalline cellulose, 10% resistant dextrin, 3% magnesium ...

Embodiment 2

[0058] This embodiment provides a bitter gourd polypeptide buccal tablet with hypoglycemic effect, and the bitter gourd polypeptide buccal tablet includes:

[0059] Bitter melon polypeptide extract 3Kg, planted ginseng extract concentrate 4Kg, Pueraria flavonoids extract 1Kg, Polygonatum polysaccharide extract 3Kg, nutritional yeast 0.6‰. Among them, the content of balsam pear polypeptide in the balsam pear polypeptide extract is 23%, wherein the content of balsam pear polypeptide with a molecular weight of 5.5-7kDa is 18%; the content of ginsenosides in the planted ginseng extract concentrate is 24%; The content of Polygonatum Polysaccharides is 50%; the content of Polygonatum Polysaccharides in Polygonatum Polysaccharides Extract is 26%.

[0060]The preparation method of the bitter gourd polypeptide compound buccal tablet comprises:

[0061] a. Mix bitter gourd polypeptide extract, planting ginseng extract concentrate, kudzu flavonoid extract, Polygonatum polysaccharide ext...

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Abstract

The invention provides bitter gourd and polypeptide composite buccal tablets capable of reducing blood sugar and a preparation method of the bitter gourd and polypeptide composite buccal tablets, andbelongs to the fields of nutritive special meals and functional foods. The bitter gourd and polypeptide composite buccal tablets comprise the following components in parts by weight: 3-5 parts of a bitter gourd polypeptide extract, 2-4 parts of a planted ginseng concentrate, 1-3 parts of a kudzuvine root extract, 1-3 parts of a rhizoma polygonati extract and 0.06-0.08% of nutritive yeast. The preparation method of the bitter gourd and polypeptide composite buccal tablets comprises the following steps of uniformly mixing the raw materials with auxiliary materials according to the formula quantity, then performing drying, performing screening, performing sterilization so as to obtain mixed powder materials, and performing direct dry-method tabletting according to specifications. The contentof bitter gourd polypeptide protein in the bitter gourd polypeptide extract is 20% or above, the content of bitter gourd polypeptide fragments of which the molecular weight is 5.5-7 kDa is 18-25%, andinsulin receptors of the polypeptide fragments are high in combining capacity. The bitter gourd and polypeptide composite buccal tablets are reasonable in edible and medical formula, the dry-method tabletting is high in quality controllability, and the bitter gourd and polypeptide composite buccal tablets have remarkable effects of reducing blood sugar and adjusting and controlling glycometabolism for patients suffering from diabetes and patients at the early stage of diabetes.

Description

technical field [0001] The invention relates to the field of nutritional special diet and functional food, in particular to a hypoglycemic bitter gourd polypeptide compound buccal tablet and a preparation method thereof. Background technique [0002] With the continuous improvement of people's living standards and the rapid development of social economy, the number of diabetic patients in my country has shown a rapid growth trend, accounting for about one-third of the total number of diabetic patients in the world. At present, the incidence of diabetes in my country is as high as 9.6%, and the number of diabetic patients has exceeded 110 million, and the number of patients is still increasing year by year. The harm of diabetes is huge, and the complications of diabetes accompanied by diabetes also pose a huge threat to the health and life of patients. Diabetes is called diabetes in ancient times, and it refers to a syndrome characterized by polydipsia, polyuria, polyphagia,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/18A23L33/105A23L33/125A23L33/14
Inventor 何静仁郑皓
Owner 何静仁
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