Preparation method of biomedical ordered porous as-cast zinc-based material

Abstract

The invention discloses a preparation method of a biomedical ordered porous as-cast zinc-based material. The preparation method comprises the following steps that (1) a porous titanium preform with the same pore structure is prepared according to the actual requirements of the structure of the porous as-cast zinc-based material by utilizing a selective laser melting (SLM) technology; (2) uniaxialcompression is adopted to infiltrate the NaF slurry prepared in advance into the open pore structure of porous titanium, sintering is carried out, and a porous titanium-NaF composite preform is obtained; (3) the composite preform is placed in a hydrogen fluoride (HF) acid mist environment, and a NaF preform is obtained after the porous titanium is completely corroded; (4) the NaF preform is filledwith a zinc-based metal solution by using a seepage casting principle, and the solution is cooled and solidified in air; (5) the NaF preform is dissolved and removed by using deionized water, and therefore the ordered porous as-cast zinc-based material with the excellent mechanical property is obtained.

Description

technical field [0001] This field belongs to the technical field of biomaterial preparation, and in particular relates to a method for preparing biomedical ordered and porous cast zinc-based materials. Background technique [0002] Large bone defects caused by trauma, infection, tumor, congenital deformity and other diseases have always been a major problem in clinical repair surgery. In the treatment of such bone defects, autologous bone or allogeneic bone transplantation is generally used, but there are still many problems such as insufficient donor materials, human immune rejection and so on. Since Vacanti et al. proposed bone tissue engineering in 1987, it has achieved rapid development as a new discipline. Bone tissue engineering is mainly by planting seed cells and biological regulatory factors on the scaffold material, and after implanting it into the bone defect site, the scaffold material degrades while the cells proliferate and differentiate, and finally achieves ...

AI Technical Summary

Problems solved by technology

For the commonly used powder metallurgy method, the obtained porous material has poor connectivity between the pore structures, and the porosity is generally 30% to 70%, which cannot realize the bionic structure similar to human cancellous bone (the porosity is as high as 80% or more)

In contrast, the infiltration casting method is simple and flexible, and the obtained porous material has better pore structure connectivity and a porosity ≥ 75%, but similar to the powder metallurgy method, the pore structure of the material is difficult to achieve quantitative control according to actual needs

In addition, porous materials prepared by 3D printing technology, especially for metal materials, have more microscopic defects, and the mechanical properties are far from being comparable to cast metal products.

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