Venom protein gel and preparation method thereof

A technology of snake venom and gel, which is applied in the fields of peptide/protein components, anti-inflammatory agents, pharmaceutical formulas, etc. It can solve the problems of snake venom that have not been seen yet, and achieve the effect of improving drug efficacy and thickening effect
CN110201146APending Publication Date: 2019-09-06NANJING ANGGU PHARMA TECH
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
NANJING ANGGU PHARMA TECH
Publication Date
2019-09-06

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Abstract

The invention discloses a venom protein gel. The venom protein gel is characterized by comprising venom protein dry powder, a gel matrix, a transdermal absorption promoter, a protein protective agent,a pH regulator, a solvent and other pharmaceutically acceptable auxiliary materials; the gel matrix is carbomer 940; the transdermal absorption promoter is essential oil; the protein protective agentis mannitol; and the pH regulator is a compound of triethanolamine and sodium bicarbonate. The venom protein gel has the characteristic of zero-order drug release.
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Description

technical field

[0001] The invention relates to a snake venom gel and a preparation method thereof. Background technique

[0002] Snake venom is a kind of toxic protein and polypeptide substances secreted by poisonous snakes that contain various enzymes, and it is also a substance that causes poisoning reactions after a poisonous snake bites a person. Fresh snake venom is an egg white-like viscous liquid with a slight fishy smell, which is yellow, light yellow, green, or even colorless. It is neutral or weakly acidic when it is fresh, and it can become alkaline after a long time. The water content is 50%-75%, and the specific gravity is between 1.030-1.080. Fresh venom is easy to produce foam when exposed to air, and it is easy to spoil and deteriorate after being placed at room temperature for 24 hours, losing its toxicity. It can be kept in the refrigerator for 15-30 days, and it can be stored at -40°C for a long time. After vacuum drying or freeze-drying, the snake veno...

Claims

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