A kind of glucosamine bone glue peptide calcium granule

A technology of granules and collagen peptides, applied in the field of medicine, can solve the problems of increasing bone density, which is difficult to achieve, and achieve the effect of increasing bone density, improving resistance, and synergistic bone function

Active Publication Date: 2020-10-09
SHANDONG RUNDE BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, supplementing bone collagen or glucosamine alone is difficult to achieve the effect of increasing bone density and delaying aging

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] In parts by weight, take 45 parts of bone collagen peptide, 25 parts of glucosamine sulfate calcium salt, 13 parts of Antarctic krill oil, 7 parts of isomaltooligosaccharide, 4 parts of D-ribose, 4 parts of oat essence, 5 parts of seaweed Polysaccharide, 10 parts of dried shrimp powder, 7 parts of vitamin D3, 7 parts of fish oil, and appropriate amount of microcrystalline cellulose, magnesium stearate, and silicon dioxide were used to prepare glucosamine bone glue calcium granules.

[0029]Wherein the preparation method of glucosamine sulfate calcium salt is as follows: get 1 kg of chitin and 1 L of 1-butyl-3-methylimidazole methyl sulfate, 3 L of sulfuric acid with a mass concentration of 25% at a temperature of 40 ° C Mix and stir under the conditions to obtain a crude mother liquor, and then use a diaphragm pump to continuously pump it into a microporous membrane filter to filter to obtain a fine mother liquor; mix the prepared fine mother liquor with 1-propylsulfanoy...

Embodiment 2

[0031] In parts by weight, take 40 parts of bone collagen peptide, 20 parts of glucosamine sulfate calcium salt, 10 parts of N-acetylglucosamine, 10 parts of Antarctic krill oil, 5 parts of isomaltooligosaccharide, 3 parts of D-ribose, 2 parts of oat essence, 3 parts of seaweed polysaccharide, 8 parts of shrimp skin powder, 5 parts of vitamin D3, 5 parts of fish oil, and appropriate amount of microcrystalline cellulose, magnesium stearate, and silicon dioxide were used to prepare glucosamine bone gel peptide calcium granules.

[0032] Wherein the preparation method of glucosamine sulfate calcium salt is as follows: get 1 kg of chitin and 2 L of 1-butyl-3-methylimidazole methyl sulfate, 4 L of sulfuric acid with a mass concentration of 20% at a temperature of 35 ° C The crude mother liquor is obtained by mixing and stirring at a low temperature, and then continuously pumped into a microporous membrane filter by a diaphragm pump to filter to obtain a fine mother liquor; The ioni...

Embodiment 3

[0034] In parts by weight, take 50 parts of bone collagen peptide, 30 parts of glucosamine sulfate calcium salt, 15 parts of Antarctic krill oil, 10 parts of isomaltooligosaccharide, 6 parts of D-ribose, 5 parts of oat essence, 7 parts of seaweed Polysaccharides, 13 parts of shrimp powder, 9 parts of vitamin D3, 9 parts of fish oil, and appropriate amount of microcrystalline cellulose, magnesium stearate, and silicon dioxide were used to prepare glucosamine bone gel peptide calcium granules.

[0035] Wherein the preparation method of glucosamine sulfate calcium salt is as follows: get 1 kg of chitin and 1 L of 1-butyl-3-methylimidazole methyl sulfate, 2 L of sulfuric acid with a mass concentration of 30% at a temperature of 45 ° C Mix and stir under the conditions to obtain a crude mother liquor, and then use a diaphragm pump to continuously pump it into a microporous membrane filter to filter to obtain a fine mother liquor; mix the prepared fine mother liquor with 1-propylsulf...

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PUM

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Abstract

The invention belongs to the medical field and discloses glucosamine bone glue peptide calcium granules. The glucosamine bone glue peptide calcium granules comprises bone collagen peptide, glucosamine, euphausia superb oil, isomaltooligosaccharide, D-ribose, oat essence, algal polysaccharides, dried small shrimp meal, vitamin D3, fish oil and pharmaceutical adjutants. The bone collagen peptide, the glucosamine, the dried small shrimp meal and the euphausia superb oil in the glucosamine bone glue peptide calcium granules can be absorbed by a human body easily, are jointly used for increasing bone density and recovering bone functions, have a synergistic effect and can enhance resistance, maintain beauty and care skin.

Description

technical field [0001] The invention relates to the field of medicine, in particular to an aminoglucose bone glue peptide calcium granule. Background technique [0002] Bone mineral density is the main indicator of bone strength, an important sign of bone quality, and an important basis for reflecting the degree of osteoporosis and predicting the risk of fracture. People's bone density reaches its peak at about 30 years old, and then it will decline year by year due to bone loss with age. According to reports, regardless of men and women, after the age of 60, bone loss generally reaches 20% to 30% of the peak value, and the maximum can reach 40%. With the growth of age, compared with young people under the age of 30 under the same nutritional conditions, middle-aged and elderly people still inevitably suffer from a large amount of bone loss, decreased bone density, decreased bone strength, and gradually become loose and easy to break. Therefore, middle-aged and elderly peo...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/39A61K9/16A61K47/38A61P19/10C07H1/00C07H5/06A61K31/593A61K31/7004A61K31/7008A61K31/702A61K31/715A61K35/60A61K35/612
CPCA61K9/1652A61K31/593A61K31/7004A61K31/7008A61K31/702A61K31/715A61K35/60A61K35/612A61K38/39A61P19/10C07H1/00C07H5/06A61K2300/00
Inventor 卢健行马善丽吴祥舟赵鹏卢建智
Owner SHANDONG RUNDE BIOTECH CO LTD
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