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A kind of antioxidant composition and its application and product

An anti-oxidation and composition technology, applied in the field of skin care products, can solve the problems of induced aging, oxidative stress, lipid peroxidation, etc.

Active Publication Date: 2022-07-12
HUNAN YUJIA COSMETICS MFG CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But sometimes because of external influences, endogenous diseases, etc., this balance will be broken, causing damage to the skin
Usually, such oxidizing substances include active oxygen, active nitrogen, hydroxyl radicals, superoxide anions, singlet oxygen, hydrogen peroxide, hypochlorous acid, ozone, etc., through electron transfer, free radical addition reactions, etc. , resulting in many problems such as oxidative stress and lipid peroxidation
[0004] Furthermore, the active oxygen and free radicals brought about by the imbalance of redox state of the skin will not only induce aging, but also cause other skin problems

Method used

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  • A kind of antioxidant composition and its application and product
  • A kind of antioxidant composition and its application and product
  • A kind of antioxidant composition and its application and product

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1～3 and comparative example 1～2

[0042]The compositions of Examples 1 to 3 and Comparative Examples 1 to 2 are shown in Table 1, and Examples 1 to 3 are antioxidant compositions of the present invention.

[0043] Table 1

[0044] component Comparative Example 1 Example 1 Example 2 Example 3 Comparative Example 2 Ganoderma lucidum fermentation broth 10 7 5 3 0 Dandelion Extract 0 3 5 7 10

Embodiment 4 and comparative example 3～4

[0076] The cosmetic water preparations of Example 4 and Comparative Examples 3 to 4 were prepared according to the following table. Wherein, the cosmetic of Example 4 is composed of the antioxidant composition of Example 3, and the mass ratio of Ganoderma lucidum fermentation liquid and dandelion extract is 3:7.

[0077] Table 5. Recipe table

[0078]

[0079] Synthesize as follows:

[0080] (1) Weigh PEG / PPG-14 / 7 dimethyl ether, glycerol glucoside, betaine, add a part of deionized water and heat to about 50°C, stir and dissolve for 20min at 250~300r / min;

[0081] (2) adding phenoxyethanol and p-hydroxyacetophenone, keeping the temperature at 50°C, stirring and dissolving for 15min;

[0082] (3) Add Ganoderma lucidum extract and dandelion extract, the temperature drops to 35-45°C, stir and dissolve for 15 minutes, stir at 100 r / min for 15 minutes, and then cool to room temperature to prepare skin care products.

Embodiment 3

[0083] Test Example 3 Efficacy Evaluation

[0084] (1) Personnel recruitment: Human experiments were used to measure the changes of skin hemoglobin, and 30 volunteers aged 18-30 who met the requirements were selected as the test subjects. Recruitment criteria: The skin is fragile and prone to reddening due to environmental influences such as temperature difference / seasonal changes. There is already redness on the front of the test.

[0085] (2) Subject requirements:

[0086] (i) The informed consent form has been signed, and all subjects who voluntarily participate in this test accept oral and paper informed consent in accordance with local regulations and procedures. Informed consent explains the nature, purpose, and potential risks of participation in the study, and emphasizes the voluntary nature of participation in testing, and subjects may withdraw from the study at any time for any reason. All subjects may ask questions about the study, giving ample time to consider be...

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Abstract

The invention relates to the technical field of skin care products, in particular to an antioxidant composition, applications and products thereof. The antioxidant composition is composed of Ganoderma lucidum fermentation broth and dandelion extract. The invention uses Ganoderma lucidum fermentation liquid and dandelion extract in a certain proportion, which can interrupt the chain reaction in the oxidation process, destroy the oxidation process, inhibit the generation of free radicals, and show significant antioxidant effect. Experiments show that the antioxidant effect of the composition of the present invention is significantly better than that of Ganoderma lucidum fermentation broth or dandelion extract alone. Under the same DPPH free radical inhibitory ability, the dosage of the active ingredient is significantly lower than that alone, indicating that the antioxidant composition of the present invention is in the antioxidant composition of the present invention. Ganoderma lucidum fermentation broth and dandelion extract have synergistic effects on antioxidants, and both are indispensable. In addition, the effect of the composition on skin redness removal and soothing is also significantly better than that of a single dose.

Description

technical field [0001] The invention relates to the technical field of skin care products, in particular to an antioxidant composition, applications and products thereof. Background technique [0002] Solar radiation, environmental pollution, internal inflammation, etc. all generate reactive oxygen species and free radicals in the skin. The imbalance of this redox state is the root cause of many pathological diseases, including skin aging damage, skin cancer, etc. Based on the imbalance of redox, excess free radicals are continuously oxidized in a chain reaction in the body, causing cell damage. In addition, excessive free radicals will increase tyrosinase activity, speed up the process of pigment synthesis, and make it difficult for melanin particles to catabolize and accumulate gradually. Excessive free radicals also participate in the process of skin inflammation, participate in a series of signal transduction, up-regulate the expression of inflammatory factors, thereby...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9789A61K8/9728A61Q19/08A61Q19/00
CPCA61K8/9789A61K8/9728A61Q19/08A61Q19/00A61K2800/592A61K2800/85
Inventor 戴跃锋何广文颜少慰吕孙良
Owner HUNAN YUJIA COSMETICS MFG CO LTD