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Bio-based disinfectant and application thereof

A disinfectant, bio-based technology, applied in the directions of disinfectants, biocides, applications, etc., to achieve the effect of high safety, wide applicability, and no irritating odor

Pending Publication Date: 2022-08-05
COFCO NUTRITION & HEALTH RES INST +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, the bactericidal effect of current biomaterial-based disinfectants needs to be further improved

Method used

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  • Bio-based disinfectant and application thereof
  • Bio-based disinfectant and application thereof
  • Bio-based disinfectant and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach

[0041] According to a preferred embodiment of the present invention, the bio-based disinfectant contains polylysine, lysine, ethyl lauroyl arginine hydrochloride, glycerol and betaine BS12, or is composed of polylysine , Lysostaphin, lauroyl arginine ethyl ester hydrochloride, glycerol and betaine BS12 composition.

[0042] According to a preferred embodiment of the present invention, the bio-based disinfectant further contains an organic acid, for example, at least one of acetic acid, lactic acid and citric acid. In the case of containing organic acids, the disinfection effect can be further improved.

[0043] Wherein, the concentration of acetic acid may be 0.001-0.05% by weight, preferably 0.005-0.01% by weight.

[0044] Wherein, the concentration of lactic acid may be 0.001-0.8% by weight, preferably 0.1-0.5% by weight.

[0045] Wherein, the concentration of citric acid can be 0.001-0.8% by weight, preferably 0.1-0.5% by weight.

[0046] According to the present inventi...

Embodiment

[0055] The following examples will further illustrate the present invention, but do not limit the present invention accordingly.

[0056] In the following examples and comparative examples:

[0057] Polylysine was purchased from Zhejiang Yinuo Biotechnology Co., Ltd., food grade polylysine;

[0058] Lysozyme was purchased from Zhejiang Yinuo Biotechnology Co., Ltd., food grade lysozyme;

[0059] Nisin was purchased from Zhejiang Yinuo Biotechnology Co., Ltd., food grade nisin;

[0060] Lysostaphin is a Lysostaphin protein (UniprotKB-P10547) derived from Staphylococcus simulans expressed in Escherichia coli, and the expression method is conventional operations in the field of genetic engineering, such as constructing the pET28a vector and transferring it into the BL21 (DE3) expression strain for induced expression. , and then purify the protein.

[0061] Examples and Comparative Examples

[0062] The bio-based disinfectant was prepared according to the components and dosage...

Embodiment 7

[0068] This example is used to illustrate the disinfectant provided by the present invention

[0069] The preparation of the disinfectant was carried out according to the method of Example 1, except that deionized water was used to replace the buffer.

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Abstract

The invention relates to the field of disinfectants, in particular to a bio-based disinfectant and application thereof. The bio-based disinfectant is prepared from polylysine, lysozyme and / or lysostaphin, ethyl lauroyl arginate hydrochloride and glycerol, in the bio-based disinfectant, the concentration of the polylysine is 0.01 to 5 weight percent, the concentration of the lysozyme and / or the lysostaphin is 0.01 to 5 weight percent, the concentration of the ethyl lauroyl arginate hydrochloride is 0.01 to 5 weight percent, and the concentration of the glycerol is 0.01 to 10 weight percent. The disinfectant provided by the invention has the characteristics of high antibacterial rate, high safety, wide antibacterial spectrum, wide applicability, mildness and durability.

Description

technical field [0001] The present invention relates to the field of disinfectants. More specifically, the present invention relates to a bio-based disinfectant and its application. Background technique [0002] At present, the disinfection products in daily use are generally chemical preparations. According to their main active ingredients, they can be divided into chlorine-containing disinfectants, phenol-containing disinfectants, peroxide-based disinfectants, aldehyde-based disinfectants, alcohol-based disinfectants, and phenol-based disinfectants. agent, biguanide disinfectant, quaternary ammonium salt disinfectant, etc. Aldehyde, phenol, and biguanide disinfectants have high bactericidal effects, but their components are toxic; chlorine-containing disinfectants and peroxide-based disinfectants are irritating, and if they are handled improperly, there will be potential safety hazards; alcohol Class disinfectants, iodine-containing disinfectants, and quaternary ammonium...

Claims

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Application Information

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IPC IPC(8): A61K38/48A61K47/10A61K47/12A61P17/00A61P31/02A01N63/50A01N37/46A01N47/44A01N43/90A01P1/00A01P3/00A61K31/198A61K31/785A61K38/16A61K38/47
CPCA61K38/47C12Y302/01017A61K38/4886C12Y304/24075A61K31/785A61K31/198A61K38/164A61K47/10A61K47/12A61P17/00A61P31/02A01N63/50A01N37/46A01N47/44A01N43/90A61K2300/00Y02A50/30
Inventor 张媛周娜娜王靖王小艳陈博安泰沈雪梅杨娟杨凯
Owner COFCO NUTRITION & HEALTH RES INST
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